Protein Alignment Ugt302C1 and Ugt1a6

DIOPT Version :10

• Sequence 1: NP_652626.1
• Gene: Ugt302C1 / 53510
• FlyBaseID: FBgn0040259
• Length: 528
• Species: Drosophila melanogaster
• Sequence 2: NP_476446.2
• Gene: Ugt1a6 / 113992
• RGDID: 620949
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 552
• Identity: 165/552 - (29%)
• Similarity: 259/552 - (46%)
• Gaps: 70/552 - (12%)

  Fly     9 GFLALLLFCLLSCVSAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVTIISPFELKKPIKNIKD 73
            |||.|:|:   ..|.....|||....  ||:.....:.:.|:..||.:.::.| |:...:...|.
  Rat    13 GFLFLVLW---GSVLGDKLLVVPQDG--SHWLSMKEIVEHLSERGHDIVVLVP-EVNLLLGESKY 71

  Fly    74 VPAKSI-----LTSMQGR---IANLLQSSKEPIIKQIINFHEMGIEI------TELLLKEPSVIE 124
            ...||.     |..::.|   ..|...::..|::..:..:....|.|      .:.|||:.:.:.
  Rat    72 YRRKSFPVPYNLEELRTRYRSFGNNHFAASSPLMAPLREYRNNMIVIDMCFFSCQSLLKDSATLS 136

  Fly   125 LMKSNQTFDAVISE------VFLNEAHFGFAEHFKAPLIGLGTFGAISWNTDLVGSPSPPSYVPS 183
            .::.|| |||:.::      |.|       ||:.|.|.:.|......|....|..||||.||||.
  Rat   137 FLRENQ-FDALFTDPAMPCGVIL-------AEYLKLPSVYLFRGFPCSLEHMLGQSPSPVSYVPR 193

  Fly   184 ALLKFSDRMSLVERVGNQAFLTYEYIFLNYFYLPRQEVLYRKY-------------FPNNKQDFY 235
            ...||||.|:..:|:.|  |:.  .|..||.|    ..||.||             .|...|:
  Rat   194 FYTKFSDHMTFPQRLAN--FIA--NILENYLY----HCLYSKYEILASDLLKRDVSLPALHQN-- 248

  Fly   236 DMRKNTALVLLNQHVSLSFPRPYSPNMIEVGGMHINRKRQPLPKDILEFIEGA-EHGVIYFSMGS 299
                  :|.||.......:|||..||||.:||.:. :|:..|.::...::..: |||::.||:||
  Rat   249 ------SLWLLRYDFVFEYPRPVMPNMIFIGGTNC-KKKGNLSQEFEAYVNASGEHGIVVFSLGS 306

  Fly   300 NLKSKTLPLEKRQALIDTFAQLKQRVLWKFEDTDLPGKPANVFISDWFPQDDILAHDNVLAFITH 364
            .:..  :|.:|...:.:...::.|.|||::..|.......|..:..|.||:|:|.|....|||||
  Rat   307 MVSE--IPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARAFITH 369

  Fly   365 GGLLSTTESIYHRKPFVGIPIFGDQFLNMARAEQNGYGVTVHYEELSSAKLLAAIQKIINNPEAT 429
            .|.....|.|.:..|.|.:|:||||..|..|.|..|.|||::..|:::..|..|::.:|||....
  Rat   370 SGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYK 434

  Fly   430 QRVRDMSDRYRDQQQTPLERAVYWVEHVSRHKGAKYLRSASQDLNFIQYHNLDAMLILYGGIIFV 494
            :.:..:|..::|:...||:.||:|||:|.|||||.:||.|:.||.:.|||:||.:..|   :..|
  Rat   435 ENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFL---LAIV 496

  Fly   495 LYCIFLLIRLVWRLLQELFIKKDTSKPKQKAK 526
            |..:|::.:......::.|..|...|...|:|
  Rat   497 LTVVFIVYKSCAYGCRKCFGGKGRVKKSHKSK 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	Glycosyltransferase_GTB-type	<185..507	CDD:471961	110/335 (33%)
Ugt1a6	NP_476446.2	UDPGT	26..521	CDD:278624	156/527 (30%)