Protein Alignment Ugt302C1 and UGT2B11

DIOPT Version :10

• Sequence 1: NP_652626.1
• Gene: Ugt302C1 / 53510
• FlyBaseID: FBgn0040259
• Length: 528
• Species: Drosophila melanogaster
• Sequence 2: NP_001064.1
• Gene: UGT2B11 / 10720
• HGNCID: 12545
• Length: 529
• Species: Homo sapiens
• Alignment Length: 583
• Identity: 168/583 - (28%)
• Similarity: 260/583 - (44%)
• Gaps: 126/583 - (21%)

  Fly    12 ALLLFCLLSCV--SAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVTIIS-------------- 60
            ::||...|||.  |.....|::..|..||:.....:.|.|...||:||:::
Human     7 SVLLLIHLSCYFSSGSCGKVLVWAAEYSHWMNMKTILKELVQRGHEVTVLASSASILFDPNDAST 71

  Fly    61 ------PFELKK---------PIKNIKDVPAKS----------ILTSMQGRIANLLQS--SKEPI 98
                  |..|.|         .:|...|:...|          ||..:.....|..:.  |.:.:
Human    72 LKFEVYPTSLTKTEFENIIMQQVKRWSDIRKDSFWLYFSQEQEILWELYDIFRNFCKDVVSNKKV 136

  Fly    99 IKQI------INFHEMGIEITELLLKEPSVIELMKSNQTFDAVISEVFLNEAHFGFAEHFKAPLI 157
            :|::      |.|.:......|||      ..|:.....:....:..:..|.|.|
Human   137 MKKLQESRFDIVFADAVFPCGELL------AALLNIRFVYSLRFTPGYTIERHSG---------- 185

  Fly   158 GLGTFGAISWNTDLVGSPSPPSYVPSALLKFSDRMSLVERVGNQAFLTY-EYIF-------LNYF 214
                           |...||||:|..:.|.||:|:.:|||.|..::.| ::.|       .:.|
Human   186 ---------------GLIFPPSYIPIVMSKLSDQMTFMERVKNMIYVLYFDFWFQMSDMKKWDQF 235

  Fly   215 YLPRQEVLYRK---YFPNNKQDFYDMRKNTALVLLNQHVSLSFPRPYSPNMIEVGGMHINRKRQP 276
            |   .|||.|.   :....|.|.:.||.:.         |..||.|:.||:..|||.|. :..:|
Human   236 Y---SEVLGRPTTLFETMGKADIWLMRNSW---------SFQFPHPFLPNVDFVGGFHC-KPAKP 287

  Fly   277 LPKDILEFIEGA-EHGVIYFSMGSNLKSKTLPLEKRQALIDTFAQLKQRVLWKFEDTDLPGKPAN 340
            |||::.||::.: |:||:.||:||.:.:.|  .|:...:....|::.|:|||:|:.........|
Human   288 LPKEMEEFVQSSGENGVVVFSLGSVISNMT--AERANVIATALAKIPQKVLWRFDGNKPDALGLN 350

  Fly   341 VFISDWFPQDDILAHDNVLAFITHGGLLSTTESIYHRKPFVGIPIFGDQFLNMARAEQNGYGVTV 405
            ..:..|.||:|:|.|....|||||||.....|:|||..|.||||:|.||..|:|..:..|..|.:
Human   351 TRLYKWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFFDQPDNIAHMKAKGAAVRL 415

  Fly   406 HYEELSSAKLLAAIQKIINNPEATQRVRDMSDRYRDQQQTPLERAVYWVEHVSRHKGAKYLRSAS 470
            .:..:||..||.|::.:||:|...:.:..:|....||...||:|||:|:|.|..|||||:||.|:
Human   416 DFNTMSSTDLLNALKTVINDPLYKENIMKLSRIQHDQPVKPLDRAVFWIEFVMPHKGAKHLRVAA 480

  Fly   471 QDLNFIQYHNLDA---MLILYGGIIFVL--YCIFLLIRLVWRLLQELFIKKDTSKPKQKAKRN 528
            .||.:.|||:||.   :|.....:||::  :|:|..    |:     |.:|.     :|.||:
Human   481 HDLTWFQYHSLDVIGFLLACVATVIFIITKFCLFCF----WK-----FARKG-----KKGKRD 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	Glycosyltransferase_GTB-type	<185..507	CDD:471961	120/338 (36%)
UGT2B11	NP_001064.1	UDPGT	24..525	CDD:278624	159/560 (28%)