DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt302C1 and ugt5c1

DIOPT Version :9

Sequence 1:	NP_652626.1	Gene:	Ugt302C1 / 53510	FlyBaseID:	FBgn0040259	Length:	528	Species:	Drosophila melanogaster
Sequence 2:	NP_001170966.1	Gene:	ugt5c1 / 100415793	ZFINID:	ZDB-GENE-050419-68	Length:	531	Species:	Danio rerio

Alignment Length:	508	Identity:	145/508 - (28%)
Similarity:	235/508 - (46%)	Gaps:	69/508 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 SHYHVGSALAKGLAAAGHQVTIIS-------------------PFELKKPIKNIKDVPAKSI--- 79
            ||:.....|.|.|...||.|.:|.                   |.......:.::||..|.|
Zfish    38 SHWVNMDILIKALHGQGHTVDVIRNTNSWFVKENSTYYNSITIPDSKGMDEEFVEDVLTKKIDYE 102

  Fly    80 --LTSMQGRIANLLQSSKEPIIKQIINFHEMGIEITELLLKEPSVIELMKSNQTFDAVISEVFLN 142
              ..|..|.:...|..|     |.:...|::...:...:.:...:::.::..:      .::.|.
Zfish   103 RGKGSWLGGVQLFLDVS-----KAVYESHKLVCRLITNIFESEDILKALQEKK------YDLMLT 156

  Fly   143 EAHFG----FAEHFKAPLIGLGTFGAISWNTDLVG----SPSPPSYVPSALLKFSDRMSLVERVG 199
            :..:|    .|...|.|::     ..:.|.|...|    :|||.||:|......:|:||..:||.
Zfish   157 DPGWGTGIILAHKLKLPMV-----YNVRWTTPGEGHFDIAPSPMSYIPLTGSGNTDKMSFFQRVI 216

  Fly   200 NQAFLTYEYIFLNY----FYLPRQEVLYRKYFPNNKQDFYDMRKNTALVLLNQHVSLSFPRPYSP 260
            |    .:.|:.|::    |.:|:.:.|..||| :...|||.:.:...|.|:.......||||..|
Zfish   217 N----VFYYLLLDFQCSRFNVPQYQALCDKYF-DPPVDFYKLLQGADLWLMRVDFVFEFPRPTMP 276

  Fly   261 NMIEVGGMHINRKRQPLPKDILEFIEGA-EHGVIYFSMGSNLKSKTLPLEKRQALIDTFAQLKQR 324
            |:|..||.... ..:|||.|:.:|::.: :||||..|:||.:  ..||......:...||:|.|:
Zfish   277 NIIYTGGFQCT-PTKPLPHDLEDFMQSSGDHGVIVMSLGSFI--SVLPDYVSSEIAAAFARLPQK 338

  Fly   325 VLWKFEDTDLPGKPA----NVFISDWFPQDDILAHDNVLAFITHGGLLSTTESIYHRKPFVGIPI 385
            |:|::...    ||:    |..:.||.||.|:|.|.....||.|||.....|::||..|.:|||.
Zfish   339 VIWRYTGK----KPSTLGNNTLLVDWMPQKDLLGHPKTKLFIAHGGTNGVQEALYHGVPVIGIPF 399

  Fly   386 FGDQFLNMARAEQNGYGVTVHYEELSSAKLLAAIQKIINNPEATQRVRDMSDRYRDQQQTPLERA 450
            |.||:.|:.|.:..|....|...||....|.||||::||.|.....::.:|..:||:...||:.|
Zfish   400 FFDQYDNLIRLQARGGAKIVSLAELGENSLHAAIQEVINEPSYRLNMQKLSYLHRDKPVEPLDSA 464

  Fly   451 VYWVEHVSRHKGAKYLRSASQDLNFIQYHNLDAMLILYGGIIFVLYCIFLLIR 503
            ::|:|.|.|||||.:||:.|..:.:..||::|..:.|...::..:|.:|:.:|
Zfish   465 IFWIEFVMRHKGAAHLRTESYKMPWYSYHSVDVSVTLIAVVLIFIYSMFVTVR 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	115/365 (32%)
ugt5c1	NP_001170966.1	UDPGT	28..530	CDD:278624	145/508 (29%)
ugt5c1	NP_001170966.1	egt	<267..507	CDD:223071	89/246 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170585105
Domainoid	1	1.000	252	1.000	Domainoid score	I2043
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	252	1.000	Inparanoid score	I3189
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm6444
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	10.690