Protein Alignment Ugt302E1 and Ugt2a1

DIOPT Version :10

• Sequence 1: NP_652625.2
• Gene: Ugt302E1 / 53508
• FlyBaseID: FBgn0040257
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_444414.2
• Gene: Ugt2a1 / 94215
• MGIID: 2149905
• Length: 528
• Species: Mus musculus
• Alignment Length: 522
• Identity: 152/522 - (29%)
• Similarity: 250/522 - (47%)
• Gaps: 72/522 - (13%)

  Fly    10 LLILALFGQSWGYSYLMISHTASKSHYAVCFALAKGL----AAAGHEVTL-VSPFP-QRKPIKNI 68
            :||..:.|..|....::|.....|.|.......:..|    ::....:|. :.|.| .::.|:::
Mouse    23 VLIWPMEGSHWLNVKIIIDELLRKEHNVTVLVASGALFITPSSISPSLTFEIYPVPFGKEKIESV 87

  Fly    69 ID-------VETPNIITVMGVYK--ARILENAKKPVLLRYPRISLMGLDITESLLKEPKVQELLK 124
            |.       ...|:..|:...||  |:::|           ...|:...|.:.:||..|:...|:
Mouse    88 IKDFVLTWLENRPSPSTIWTFYKEMAKVIE-----------EFHLVSRGICDGVLKNEKLMSKLQ 141

  Fly   125 QNRTFDGVICETFMNDAHYG----FAEHFGAPLITLSSLGATGWTSDLVG-TPSPPSYVPHSLLR 184
            :.:      .|..::|..:.    .|...|.|.|...............| .|.||||||..|..
Mouse   142 KEK------FEVLLSDPVFPCGDIVALKLGIPFIYSLRFSPASTVEKHCGKVPFPPSYVPAILSE 200

  Fly   185 FGDRMNFWERAQN-LGFQIYEFAYENLINLPRHEALYRKYFPNNKQDFYRMRKDTSLV------- 241
            ..|:|:|.:|.:| :.:::.::.:|.|  ..:.::.|.|          .:.:.|:|.
Mouse   201 LTDQMSFTDRVRNFISYRMQDYMFETL--WKQWDSYYTK----------ALGRPTTLCETMGKAE 253

  Fly   242 --LLNNHVSISNPRPYSPNMIEVGGMHVNRKAPKPLPQNIRKFIE-EAEHGVIYFSLGSNLNSKD 303
              |:..:.....||||.||...|||:|.  |..||||:.:.:|:: ..|||::.|||||.:  |:
Mouse   254 IWLMRTYWDFEFPRPYLPNFEFVGGLHC--KPAKPLPKEMEEFVQTSGEHGIVVFSLGSMV--KN 314

  Fly   304 LPENKRKAIVETLRGLKYRVIWKYEEETFVDKPD----NVLISNWLPQDDILAHEKVIAFITHGG 364
            |.:.|...|...|..:..:|:|:|:.:.    ||    |..:.:|:||:|:|.|.|..|||||||
Mouse   315 LTDEKANLIASALAQIPQKVLWRYKGKI----PDTLGSNTRLFDWIPQNDLLGHPKTRAFITHGG 375

  Fly   365 LLSTMESIYHGKPVVGIPFFGDQFMNMARAEQMGYGITVKYAQLTASLFRSAIERITSDPSFTER 429
            .....|:||||.|:||:|.|.||..|:|..:..|..:.|....:|:|...:|:..:.::||:.|.
Mouse   376 TNGIYEAIYHGIPMVGVPMFADQPDNIAHMKAKGAAVEVNMNTMTSSDLLNALRTVINEPSYKEN 440

  Fly   430 VKVISSQYRDQKETPLERAVYWVEHVTRHKGAKYLRSACQDLNFIQYHNLDVLATFFSVIGLTVI 494
            ...:|..:.||...||:|||:|:|.|.||||||:||.|..||::.|||:|||:....:.:...::
Mouse   441 AMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLACVASAIL 505

  Fly   495 FV 496
            .|
Mouse   506 LV 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302E1	NP_652625.2	Glycosyltransferase_GTB-type	<170..496	CDD:471961	120/341 (35%)
Ugt2a1	NP_444414.2	UDPGT	21..516	CDD:278624	152/522 (29%)