DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt302E1 and UGT85A3

DIOPT Version :9

Sequence 1:	NP_652625.2	Gene:	Ugt302E1 / 53508	FlyBaseID:	FBgn0040257	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_173655.2	Gene:	UGT85A3 / 838845	AraportID:	AT1G22380	Length:	488	Species:	Arabidopsis thaliana

Alignment Length:	531	Identity:	109/531 - (20%)
Similarity:	189/531 - (35%)	Gaps:	183/531 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 AAGHEVTLVSPFPQRKPIKNIIDVETPNIITVMGVYK-ARILENAKKPVLLRYPRISL------- 104
            |.||    ::|..:   :..::.|:..::..|..||. .|:|.:.....|...|....
plant    21 AQGH----INPMMK---VAKLLHVKGFHVTFVNTVYNHNRLLRSRGANALDGLPSFQFESIPDGL 78

  Fly   105 --MGLDIT-------ESLLKEPKV--QELLKQNRTFDGVICETFMNDAHYGFAEHFGAPLITLSS 158
              .|:|.|       ||..|...|  ::||::..|.:.|                  .|:..:.|
plant    79 PETGVDATQDIPALSESTTKNCLVPFKKLLQRIVTREDV------------------PPVSCIVS 125

  Fly   159 LGATGWTSDL---VGTPSPPSYVPHSLLRFGDRMNFWERAQNLGF----QIYEFAYENLINLPRH 216
            .|:..:|.|:   :|.|               .::||..:. .||    ..|.|..:.|..:...
plant   126 DGSMSFTLDVAEELGVP---------------EIHFWTTSA-CGFMAYLHFYLFIEKGLCPVKDA 174

  Fly   217 EALYRKYF--------------------------PNNKQDFYRMR-----KDTSLVLLN-----N 245
            ..|.::|.                          ||:....:.:|     |..|.::||     .
plant   175 SCLTKEYLDTVIDWIPSMNNVKLKDIPSFIRTTNPNDIMLNFVVREACRTKRASAIILNTFDDLE 239

  Fly   246 HVSISNPRPYSPNMIEVGGMH--VNRKAPKP-----LPQNIRKFIEEAE----------HGVIYF 293
            |..|.:.:...|.:..:|.:|  |||:..:.     :..|:.|  ||.|          :.|:|.
plant   240 HDIIQSMQSILPPVYPIGPLHLLVNREIEEDSEIGRMGSNLWK--EETECLGWLNTKSRNSVVYV 302

  Fly   294 SLGSNLNSKDLPENKRKAIVETLRGLKYRVIWKY----EEETFVDKPDNV--------------- 339
            :.||            ..|:.|.:.|::  .|..    :|..:|.:||:|
plant   303 NFGS------------ITIMTTAQLLEF--AWGLAATGKEFLWVMRPDSVAGEEAVIPKEFLAET 353

  Fly   340 ----LISNWLPQDDILAHEKVIAFITHGGLLSTMESIYHGKPVVGIPFFGDQFMNMA-RAEQMGY 399
                ::::|.||:.:|:|..|..|:||.|..||:||:..|.|:|..|||.:|..|.. ..::...
plant   354 ADRRMLTSWCPQEKVLSHPAVGGFLTHCGWNSTLESLSCGVPMVCWPFFAEQQTNCKFSCDEWEV 418

  Fly   400 GITVKYAQLTASLFRSAIERITSDPSFTERVKVISSQYRDQKETPLERAVYWVEHVTRHKGAKYL 464
            ||     ::...:.|..:|.:..:....|:.|.:.           |:||.|     |....|..
plant   419 GI-----EIGGDVKRGEVEAVVRELMDGEKGKKMR-----------EKAVEW-----RRLAEKAT 462

  Fly   465 RSACQD--LNF 473
            :..|..  :||
plant   463 KLPCGSSVINF 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302E1	NP_652625.2	egt	<114..464	CDD:223071	89/435 (20%)
UGT85A3	NP_173655.2	Glycosyltransferase_GTB_type	9..478	CDD:299143	109/531 (21%)
UGT85A3	NP_173655.2	MGT	20..459	CDD:273616	105/515 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050