Protein Alignment Ugt302E1 and UGT8

DIOPT Version :9

• Sequence 1: NP_652625.2
• Gene: Ugt302E1 / 53508
• FlyBaseID: FBgn0040257
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_001121646.2
• Gene: UGT8 / 7368
• HGNCID: 12555
• Length: 541
• Species: Homo sapiens
• Alignment Length: 548
• Identity: 156/548 - (28%)
• Similarity: 262/548 - (47%)
• Gaps: 85/548 - (15%)

  Fly     8 WLLLILALFGQSWGYSYLMISHTASKSHYAVCFALAKGLAAAGHEVTLVSPFPQRKPIKNIIDVE 72
            :.:|:.:..|.:.....:::.....:||..:...||..|...||.
Human     7 YFILLWSAVGIAKAAKIIIVPPIMFESHMYIFKTLASALHERGHH-------------------- 51

  Fly    73 TPNIITVMGVYKARILENAKKPVLLRYP----------------------RISLMGL-DITESLL 114
                 ||..:.:.|.:..:....|.|||                      |::.:.| ||.:...
Human    52 -----TVFLLSEGRDIAPSNHYSLQRYPGIFNSTTSDAFLQSKMRNIFSGRLTAIELFDILDHYT 111

  Fly   115 K--------EPKVQELLKQNRTFDGVICETFMNDAHYGF--AEHFGAPLITLSSLGATG-WTSDL 168
            |        ...:|.|.|:.  ||.::.:.  ||. .||  |...|......|    || |....
Human   112 KNCDLMVGNHALIQGLKKEK--FDLLLVDP--NDM-CGFVIAHLLGVKYAVFS----TGLWYPAE 167

  Fly   169 VGTPSPPSYVP--HSLLRFGDRMNFWERAQNLGFQIYEFAYENLINLPRHEALYRKYFPNNKQDF 231
            ||.|:|.:|||  :|||.  ||||..:|.:|.|..:......:.:.||::|.:.:||....::..
Human   168 VGAPAPLAYVPEFNSLLT--DRMNLLQRMKNTGVYLISRLGVSFLVLPKYERIMQKYNLLPEKSM 230

  Fly   232 YRMRKDTSLVLLNNHVSISNPRPYSPNMIEVGGMHVNRKAPKPLPQNIRKFIEEA-EHGVIYFSL 295
            |.:...:||.:|...|::..|||..||::.|||  :..|...|||:::::::..| |||.:..|.
Human   231 YDLVHGSSLWMLCTDVALEFPRPTLPNVVYVGG--ILTKPASPLPEDLQRWVNGANEHGFVLVSF 293

  Fly   296 GSNLNSKDLPENKRKAIVETLRGLKYRVIWKYEEETFVDKPDNVLISNWLPQDDILAHEKVIAFI 360
            |:.:  |.|.|:....:...|..|..:|||::......:..:|..:..||||:|:|.|.|:.||:
Human   294 GAGV--KYLSEDIANKLAGALGRLPQKVIWRFSGPKPKNLGNNTKLIEWLPQNDLLGHSKIKAFL 356

  Fly   361 THGGLLSTMESIYHGKPVVGIPFFGDQFMNMARAEQMGYGITVKYAQLTASLFRSAIERITSDPS 425
            :||||.|..|:||||.||||||.|||.:..|.|.:..|.||.:::..:|......|:.::.::||
Human   357 SHGGLNSIFETIYHGVPVVGIPLFGDHYDTMTRVQAKGMGILLEWKTVTEKELYEALVKVINNPS 421

  Fly   426 FTERVKVISSQYRDQKETPLERAVYWVEHVTRHKGAKYLRSACQDLNFIQYHNLDVLATFFSVIG 490
            :.:|.:.:|..::||...|:.|.:||::::.||.||.:||:|...::|.||..||:  .|..::|
Human   422 YRQRAQKLSEIHKDQPGHPVNRTIYWIDYIIRHNGAHHLRAAVHQISFCQYFLLDI--AFVLLLG 484

  Fly   491 LTVIFVFLLVRFLVTIVNGFLYKPSSKL 518
            ..:::      ||::.|..|:|:....|
Human   485 AALLY------FLLSWVTKFIYRKIKSL 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302E1	NP_652625.2	egt	<114..464	CDD:223071	120/363 (33%)
UGT8	NP_001121646.2	Glycosyltransferase_GTB-type	21..502	CDD:415824	153/528 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150678
Domainoid	1	1.000	260	1.000	Domainoid score	I1978
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm8543
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.740