Protein Alignment Ugt302E1 and Ugt1a8

DIOPT Version :9

• Sequence 1: NP_652625.2
• Gene: Ugt302E1 / 53508
• FlyBaseID: FBgn0040257
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_001365304.1
• Gene: Ugt1a8 / 613123
• MGIID: 3576090
• Length: 530
• Species: Mus musculus
• Alignment Length: 536
• Identity: 161/536 - (30%)
• Similarity: 242/536 - (45%)
• Gaps: 110/536 - (20%)

  Fly    10 LLILALFGQSWGYSYLMISHTASKSHYAVCFALAKGLAAAGHEVTLVSP---------------- 58
            ||::.:.|..| :|..||               .:.|:..||||.:|.|
Mouse    28 LLVVPMDGSHW-FSMKMI---------------VEKLSHRGHEVVVVIPEVSWHLGKSQNFTVKT 76

  Fly    59 ---------------FPQRKPIKNIIDVETPNIITVMGVYKARILENAKK---PVLLRYPRISLM 105
                           |...|..:|          ..:|::.  :|:::.|   .||..:.|
Mouse    77 YSVSYTLEDLSHHFNFFAHKQWEN----------REVGMFS--LLKHSGKGFFQVLFSHCR---- 125

  Fly   106 GLDITESLLKEPKVQELLKQNRTFDGVICETFMNDAHYGFAEHFGAPLITLSSLGATGWTSDLVG 170
                  ||..:.|:.|.||| |:||.|..:.| :......|::|..|.:..|......:..:...
Mouse   126 ------SLFNDKKLVEYLKQ-RSFDAVFLDPF-DVCGLTIAKYFSLPSVVFSGGIFCHYLDEGAQ 182

  Fly   171 TPSPPSYVPHSLLRFGDRMNFWERAQNLGFQIYEFAYENLINLPRHEALYRKYF----------- 224
            .||||||||..|.:|.|.|.|.||..|.      |:|       ..|..:..||
Mouse   183 CPSPPSYVPRILSKFADTMTFKERVWNY------FSY-------MKERAFCPYFFKTAIEIASEV 234

  Fly   225 ---PNNKQDFYRMRKDTSLVLLNNHVSISNPRPYSPNMIEVGGMHVNRKAPKPLPQNIRKFIE-E 285
               |....|.:   ...|:.:......:..|||..|||:.:||  :|....|||.:....::. .
Mouse   235 LQTPVTMTDLF---SSVSIWMFRTDFVLEFPRPVMPNMVYIGG--INCHPGKPLSKEFEAYVNAS 294

  Fly   286 AEHGVIYFSLGSNLNSKDLPENKRKAIVETLRGLKYRVIWKYEEETFVDKPDNVLISNWLPQDDI 350
            .|||::.|||||.::  ::||.|...|.|.|..:...|:|:|......:...|.::..||||:|:
Mouse   295 GEHGIVVFSLGSMVS--EIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDL 357

  Fly   351 LAHEKVIAFITHGGLLSTMESIYHGKPVVGIPFFGDQFMNMARAEQMGYGITVKYAQLTASLFRS 415
            |.|.|..|||||.|.....|.|.:|.|:|.:|.||||..|..|.|..|.|:|:...::||....:
Mouse   358 LGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLEN 422

  Fly   416 AIERITSDPSFTERVKVISSQYRDQKETPLERAVYWVEHVTRHKGAKYLRSACQDLNFIQYHNLD 480
            |::.:.::.|:.|.:..:||.::|:...||:.||:|||:|.|||||.:||.|..||.:.|||:||
Mouse   423 ALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLD 487

  Fly   481 VLATFFSVIGLTVIFV 496
            |:. |...|.|||:|:
Mouse   488 VIG-FLLAIVLTVVFI 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302E1	NP_652625.2	egt	<114..464	CDD:223071	119/364 (33%)
Ugt1a8	NP_001365304.1	UDPGT	26..521	CDD:278624	161/536 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840363
Domainoid	1	1.000	259	1.000	Domainoid score	I1975
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2975
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm42461
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.690