DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt302E1 and ugt5g1

DIOPT Version :9

Sequence 1:	NP_652625.2	Gene:	Ugt302E1 / 53508	FlyBaseID:	FBgn0040257	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_001107914.1	Gene:	ugt5g1 / 570913	ZFINID:	ZDB-GENE-080305-10	Length:	528	Species:	Danio rerio

Alignment Length:	560	Identity:	153/560 - (27%)
Similarity:	244/560 - (43%)	Gaps:	107/560 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 RWLLNSWLLLILALFGQSWGYSYLMISHTASKSHYAVCFALAKGLAAAGHEVTLVSP-----FPQ 61
            :||  |.|..:|::.....|.:.|:.....  ||:.....:.:.|...||..|:|..     ..:
Zfish     6 KWL--SALTCLLSVVCCCHGGNILVFPEDG--SHWVNMQVILRKLHTHGHSFTVVRSSKSWYIHE 66

  Fly    62 RKPIKNIIDV----------------------------------ETPNIITVMGVYKARILENAK 92
            ...:.|.|.|                                  :..:|.||:.|:...:|.
Zfish    67 NSALYNTITVNPVETEDVGQDYFNMLLDRSLALQKMSPLVRFFEQQKDITTVLKVFHNGVLR--- 128

  Fly    93 KPVLLRYPRISLMGLDITESL--LKEPKVQELLKQNRTFDGVICETFM-------------NDAH 142
                    .:|.| ||..|.:  |:|.|...||.......||:...|:             .|||
Zfish   129 --------MVSAM-LDDAELVKSLREAKFDLLLTDPAFPAGVLVANFLQLPMVYNVRWLNAGDAH 184

  Fly   143 YGFAEHFGAPLITLSSLGATGWTSDLVGTPSPPSYVP--HSLLRFGDRMNFWERAQNLGFQIYEF 205
            ...|                         ||||||||  :|||.  |:|:|.:|.:|....:...
Zfish   185 MQTA-------------------------PSPPSYVPMYNSLLH--DQMSFLQRVENFLRYLCSL 222

  Fly   206 AYENLINLPRHEALYRKYFPNNKQDFYRMRKDTSLVLLNNHVSISNPRPYSPNMIEVGGMHVNRK 270
            ..|..:.:|.:..|..::||.. .|...|::...:.|:........|||..||:|.:||...  |
Zfish   223 LQERYVIVPIYRELLERHFPPG-SDLLSMQQSADIWLMRMDFVFDFPRPTMPNIIYMGGFQC--K 284

  Fly   271 APKPLPQNIRKFIEEA-EHGVIYFSLGSNLNSKDLPENKRKAIVETLRGLKYRVIWKYEEETFVD 334
            ..:.||.::.:|::.: ||||::.|||:.:.:  ||....:||......:..:|:|:|..|....
Zfish   285 PAQALPVDLEEFMQSSGEHGVVFMSLGAMVGA--LPRTITEAIASAFAKIPQKVMWRYHGERPST 347

  Fly   335 KPDNVLISNWLPQDDILAHEKVIAFITHGGLLSTMESIYHGKPVVGIPFFGDQFMNMARAEQMGY 399
            ..:|.|:..|.||:|:|.|.|..||::|||.....|:||||.||:.:|...|||.|:.|.:....
Zfish   348 LGNNTLLLEWFPQNDLLGHPKTRAFVSHGGTNGIYEAIYHGVPVLALPLLFDQFDNVMRLQVRNA 412

  Fly   400 GITVKYAQLTASLFRSAIERITSDPSFTERVKVISSQYRDQKETPLERAVYWVEHVTRHKGAKYL 464
            ...::.|.||:..|...::.:..:|.:...::.:|..:|||..:||:.|.:|:|:|.|||||.:|
Zfish   413 ARVLQVATLTSQEFLEGLKDVLENPLYRSSIRKMSELHRDQPISPLDSATFWIEYVMRHKGAAHL 477

  Fly   465 RSACQDLNFIQYHNLDVLATFFSVIGLTVIFVFLLV-RFL 503
            ||...:|.:..||:|||| .|...|.:...:..:.| |||
Zfish   478 RSEANNLAWYSYHSLDVL-VFLLAIAVIAFWTSVYVCRFL 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302E1	NP_652625.2	egt	<114..464	CDD:223071	110/365 (30%)
ugt5g1	NP_001107914.1	UDPGT	24..526	CDD:278624	147/540 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584641
Domainoid	1	1.000	252	1.000	Domainoid score	I2043
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	252	1.000	Inparanoid score	I3189
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm6444
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.790