Protein Alignment Ugt302E1 and Ugt2a2

DIOPT Version :9

• Sequence 1: NP_652625.2
• Gene: Ugt302E1 / 53508
• FlyBaseID: FBgn0040257
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_001019319.1
• Gene: Ugt2a2 / 552899
• MGIID: 3576095
• Length: 528
• Species: Mus musculus
• Alignment Length: 516
• Identity: 152/516 - (29%)
• Similarity: 239/516 - (46%)
• Gaps: 93/516 - (18%)

  Fly    34 SHYAVCFALAKGLAAAGHEVTLVSP---------------FPQ------RKPIKNIID------- 70
            ||:.....|.:.|....|.||:::|               |.:      :..|..||:
Mouse    32 SHWLNIKILLEELVQRNHSVTVLAPSETLFINSRLDAFINFEEIPVSYTKSKIDEIIEHMIALWL 96

  Fly    71 VETPNIITVMGVYK------ARILENAKKPVLLRYPRISLMGLDITESLLKEPKVQELLKQNRTF 129
            ...|..:|:...||      |......|:               :.:.:|..|.|.|.| |...|
Mouse    97 DHRPTPLTMWTFYKELGNLLATFYTTNKQ---------------MCDGVLNNPTVMERL-QKGGF 145

  Fly   130 DGVICE--TFMNDAHYGFAEHFGAPLI-TLSSLGATGWTSDLVGTPSPPSYVPHSLLRFGDRMNF 191
            |.::.:  |...:.   .|...|.|.: ||....|..........|:|.||||.:|....|:|:|
Mouse   146 DVLLADPVTMCGEL---VALKLGIPFVYTLRFSPAFTVERHCGKIPAPISYVPAALSELTDQMSF 207

  Fly   192 WERAQNLGFQIYEFAYENLINLPRHEALYRKYFPNNKQDFYR--MRKDTSLV---------LLNN 245
            .||.            :|:|:....:.:::.|: .....:|.  :.:.|:|.         |:..
Mouse   208 GERV------------KNIISYSLQDYIFKTYW-GEWNSYYSKVLGRPTTLCETMGKAEIWLMRT 259

  Fly   246 HVSISNPRPYSPNMIEVGGMHVNRKAPKPLPQNIRKFIE-EAEHGVIYFSLGSNLNSKDLPENKR 309
            :.....||||.||...|||:|.  |..||||:.:.:|:: ..|||::.|||||.:  |:|.:.|.
Mouse   260 YWDFEFPRPYLPNFEFVGGLHC--KPAKPLPKEMEEFVQTSGEHGIVVFSLGSMV--KNLTDEKA 320

  Fly   310 KAIVETLRGLKYRVIWKYEEETFVDKPD----NVLISNWLPQDDILAHEKVIAFITHGGLLSTME 370
            ..|...|..:..:|:|:|:.:.    ||    |..:.:|:||:|:|.|.|..|||||||.....|
Mouse   321 NLIASALAQIPQKVLWRYKGKI----PDTLGSNTRLFDWIPQNDLLGHPKTRAFITHGGTNGIYE 381

  Fly   371 SIYHGKPVVGIPFFGDQFMNMARAEQMGYGITVKYAQLTASLFRSAIERITSDPSFTERVKVISS 435
            :||||.|:||:|.|.||..|:|..:..|..:.|....:|:|...:|:..:.::||:.|....:|.
Mouse   382 AIYHGIPMVGVPMFADQPDNIAHMKAKGAAVEVNMNTMTSSDLLNALRTVINEPSYKENAMRLSR 446

  Fly   436 QYRDQKETPLERAVYWVEHVTRHKGAKYLRSACQDLNFIQYHNLDVLATFFSVIGLTVIFV 496
            .:.||...||:|||:|:|.|.||||||:||.|..||::.|||:|||:....:.:...::.|
Mouse   447 IHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLACVASAILLV 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302E1	NP_652625.2	egt	<114..464	CDD:223071	122/368 (33%)
Ugt2a2	NP_001019319.1	UDPGT	22..516	CDD:278624	152/516 (29%)
		egt	<267..487	CDD:223071	92/227 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840207
Domainoid	1	1.000	259	1.000	Domainoid score	I1975
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2975
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm42461
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.790