DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt302E1 and Ugt302K1

DIOPT Version :9

Sequence 1:	NP_652625.2	Gene:	Ugt302E1 / 53508	FlyBaseID:	FBgn0040257	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_001287281.1	Gene:	Ugt302K1 / 53502	FlyBaseID:	FBgn0040251	Length:	519	Species:	Drosophila melanogaster

Alignment Length:	514	Identity:	272/514 - (52%)
Similarity:	358/514 - (69%)	Gaps:	20/514 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LLLILALFGQSWGYSYLMISHTASKSHYAVCFALAKGLAAAGHEVTLVSPFPQRKPIKNIIDVET 73
            :|.:|...|.|.||:|||:.::|.:||:.|..||||||..|||.:|:||.|||:|||....||..
  Fly     7 ILGLLCSLGYSSGYNYLMVLNSAGRSHFNVGHALAKGLVKAGHTITVVSVFPQKKPIPGYTDVSV 71

  Fly    74 PNIITVM----GVYKARILENAKKPVLLRYPRISLMGLDITESLLKEPKVQELLKQNRTFDGVIC 134
            ||:|.||    |...|.|.:...:.::..|.    ||..||..|.::...|:.||.|::||.:||
  Fly    72 PNVIEVMGGDIGALWASIQKTYTQNLIDHYQ----MGFRITRGLFEDSNFQDFLKSNQSFDAIIC 132

  Fly   135 ETFMNDAHYGFAEHFGAPLITLSSLGATGWTSDLVGTPSPPSYVPHSLLRFGDRMNFWERAQNLG 199
            |||.||||||.||||.||||.|::.|...:.:|:||:|:|.|:|||.:|.|.|.|:.:||..|:.
  Fly   133 ETFYNDAHYGLAEHFNAPLIGLATGGGLTFITDMVGSPAPASFVPHIMLPFNDHMSLYERLLNVA 197

  Fly   200 FQIYEFAYENLINLPRHEALYRKYFPNNKQDFYRMRKDTSLVLLNNHVSISNPRPYSPNMIEVGG 264
            |..||....:...||..|.||:::||.||:.||:||::.||||:|.|||:|.|||:|||||||||
  Fly   198 FLGYERVLLDYYFLPTQEKLYKEFFPGNKRCFYKMRRNASLVLINQHVSLSFPRPHSPNMIEVGG 262

  Fly   265 MHVNRKAPKPLPQNIRKFIEEAEHGVIYFSLGSNLNSKDLPENKRKAIVETLRGLKYRVIWKYEE 329
            ||::.|. .|||:.|.:||.|:|||.||||:||||.:||||.:|.:.|::.|.|||.||:||:|.
  Fly   263 MHIDGKW-NPLPEKIERFINESEHGAIYFSMGSNLKTKDLPPSKVQEILKALGGLKQRVLWKFEL 326

  Fly   330 ETFVDKPDNVLISNWLPQDDILAHEKVIAFITHGGLLSTMESIYHGKPVVGIPFFGDQFMNMARA 394
            :...:||:||.||:|.||.|||||.|::||:||||:|||.|||||.|||:|:|.|.|||.|||.|
  Fly   327 DNLPNKPENVYISDWFPQTDILAHPKIMAFVTHGGMLSTTESIYHAKPVIGLPIFSDQFFNMAHA 391

  Fly   395 EQMGYGITVKYAQLTASLFRSAIERITSDPSFTERVKVISSQYRDQKETPLERAVYWVEHVTRHK 459
            ||.||||.:.:..|.|..||.|||||||:||:|:.|:.||.:||||::||:|.|:|||||||||:
  Fly   392 EQNGYGIMLDFKTLNAVEFRKAIERITSEPSYTKVVQGISFRYRDQQQTPIENAIYWVEHVTRHQ 456

  Fly   460 GAKYLRSACQDLNFIQYHNLDVLATFFSVIGLTVIFVFLLVRFLVTIVNGFLYKPSSKL 518
            ||.||:||.|.||:.||||:|||...|      |:.|.||:...:||     ||...||
  Fly   457 GAAYLKSAAQRLNWWQYHNVDVLLIIF------VVMVLLLIVLPITI-----YKLLKKL 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302E1	NP_652625.2	egt	<114..464	CDD:223071	200/349 (57%)
Ugt302K1	NP_001287281.1	egt	1..480	CDD:223071	260/477 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445557
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	1	0.900	-	-		E33208_3BDT1
Homologene	1	1.000	-	-		H136043
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG27372
OrthoDB	1	1.010	-	-		D30419at7147
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm6444
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	13	12.810