Protein Alignment Ugt302E1 and Ugt1a3

DIOPT Version :10

• Sequence 1: NP_652625.2
• Gene: Ugt302E1 / 53508
• FlyBaseID: FBgn0040257
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_958827.1
• Gene: Ugt1a3 / 396551
• RGDID: 1549728
• Length: 531
• Species: Rattus norvegicus
• Alignment Length: 532
• Identity: 154/532 - (28%)
• Similarity: 255/532 - (47%)
• Gaps: 78/532 - (14%)

  Fly     5 LNSWLLLILALFGQSWGYSYLMISHTASKSHYAVCFALAKGLAAAGHEVTLVSPFPQRKPIKNII 69
            |:..|||:.||   .|.....::......||:.....:.:.|.|.||:..:::|       :..:
  Rat    10 LSGLLLLLCAL---PWAEGGKVLVFPMEGSHWLSMRDVVRELHARGHQAVVLAP-------EVTV 64

  Fly    70 DVETPNIITVMGV--------YKARIL---------ENAKKPVLLRYPRISLMGLDITES----L 113
            .::..:..|:...        |:..:|         |.:.|.||.|...::.:......|    |
  Rat    65 HIKEEDFFTLQTYPVPYTKEEYRHHLLGHLQNFFETEFSLKLVLQRMAAVNNVSTFYVRSCRGLL 129

  Fly   114 LKEPKVQELLKQNRTFDGVICETFMNDAHYGFAEHFGAPLITLSSLGATGWTSDLV--------G 170
            .....:|.|  .:.:||.|:.:.|.         ..||.|.....:.|..:...::        .
  Rat   130 HNTALIQSL--NSSSFDVVLTDPFF---------PCGAVLAMYLRVPAVFFLQSMLCELEFEATN 183

  Fly   171 TPSPPSYVPHSLLRFGDRMNFWERAQNLGFQIYEFAYENLINLPRHEALYRKYFPNNKQDFYRMR 235
            :|:|.||:|..|....|.|:|.:|.:|:   :|...:..|.:: .:.:|.|.     ..|.  ::
  Rat   184 SPNPSSYIPRLLTLNSDHMSFLDRVKNM---LYPVPWMYLCHV-NYGSLARL-----ASDL--LQ 237

  Fly   236 KDTSLVLLNNHVSI---------SNPRPYSPNMIEVGGMH-VNRKAPKPLPQNIRKFIE-EAEHG 289
            ::.|:|.:..|.|:         ..|||:.|||:.:||:: .||   |||.|....::. ..|||
  Rat   238 REVSVVEILRHASVWLLRKDFVFYYPRPFMPNMVFIGGINCANR---KPLSQEFEAYVNASGEHG 299

  Fly   290 VIYFSLGSNLNSKDLPENKRKAIVETLRGLKYRVIWKYEEETFVDKPDNVLISNWLPQDDILAHE 354
            ::.|||||.::  ::||.|...|.|.|..:...|:|:|......:...|.::..||||:|:|.|.
  Rat   300 IVVFSLGSMVS--EIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHP 362

  Fly   355 KVIAFITHGGLLSTMESIYHGKPVVGIPFFGDQFMNMARAEQMGYGITVKYAQLTASLFRSAIER 419
            |..|||||.|.....|.|.:|.|:|.:|.||||..|..|.|..|.|:|:...::||....:|::.
  Rat   363 KARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKT 427

  Fly   420 ITSDPSFTERVKVISSQYRDQKETPLERAVYWVEHVTRHKGAKYLRSACQDLNFIQYHNLDVLAT 484
            :.::.|:.|.:..:||.::|:...||:.||:|||:|.|||||.:||.|..||.:.|||:|||:.
  Rat   428 VINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIG- 491

  Fly   485 FFSVIGLTVIFV 496
            |...|.|||:|:
  Rat   492 FLLAIVLTVVFI 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302E1	NP_652625.2	Glycosyltransferase_GTB-type	<170..496	CDD:471961	119/336 (35%)
Ugt1a3	NP_958827.1	UDPGT	26..522	CDD:278624	147/513 (29%)