Protein Alignment Ugt302E1 and Ugt1a1

DIOPT Version :9

• Sequence 1: NP_652625.2
• Gene: Ugt302E1 / 53508
• FlyBaseID: FBgn0040257
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_964007.2
• Gene: Ugt1a1 / 394436
• MGIID: 98898
• Length: 535
• Species: Mus musculus
• Alignment Length: 510
• Identity: 154/510 - (30%)
• Similarity: 251/510 - (49%)
• Gaps: 43/510 - (8%)

  Fly    11 LILALFGQSWGYSYLMISHTASKSHYAVCFALAKGLAAAGHEVTLVSP----------------F 59
            |:|.:||.|..::..::......||:.....:.:.|...||||.:::|                |
Mouse    17 LLLCVFGPSASHAGRLLVFPMDGSHWLSMLGVIQQLQQKGHEVVVIAPEASIHIKEGSFYTLRKF 81

  Fly    60 P---QRKPIKNIIDVETPNIITVMGVYKARILENAKKPVLLRYPRISLMGLDITESLLKEPKVQE 121
            |   |::.:...: ||..........:..|:::     :.::..|.|.|.|.....||...:...
Mouse    82 PVPFQKENVTATL-VELGRTAFNQDSFLLRVVK-----IYMKVKRDSSMLLAGCSHLLHNAEFMA 140

  Fly   122 LLKQNRTFDGVICETFMNDAHYGFAEHFGAPLITLSSLGATGWTSDLVGTPSPPSYVPHSLLRFG 186
            .|:::. ||.::.:.|:..... .|::...|.:...:.......|:....|.|.||||.||....
Mouse   141 SLEESH-FDALLTDPFLPCGSI-VAQYLTVPTVYFLNKLPCSLDSEATQCPVPLSYVPKSLSFNS 203

  Fly   187 DRMNFWERAQNLGFQIYEFAYENLINLP----RHEALYRKYFPNNKQDFYRMRKDTSLVLLNNHV 247
            |||||.:|.:|:...:.|.....::..|    ..|.|.::.   ..||   :....|:.|:.:..
Mouse   204 DRMNFLQRVKNVLLAVSENFMCRVVYSPYGSLATEILQKEV---TVQD---LLSPASIWLMRSDF 262

  Fly   248 SISNPRPYSPNMIEVGGMHVNRKAPKPLPQNIRKFIE-EAEHGVIYFSLGSNLNSKDLPENKRKA 311
            ....|||..|||:.:||::..:|  |||.|....::. ..|||::.|||||.::  ::||.|...
Mouse   263 VKDYPRPIMPNMVFIGGINCLQK--KPLSQEFEAYVNASGEHGIVVFSLGSMVS--EIPEKKAME 323

  Fly   312 IVETLRGLKYRVIWKYEEETFVDKPDNVLISNWLPQDDILAHEKVIAFITHGGLLSTMESIYHGK 376
            |.|.|..:...|:|:|......:...|.::..||||:|:|.|.|..|||||.|.....|.|.:|.
Mouse   324 IAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGV 388

  Fly   377 PVVGIPFFGDQFMNMARAEQMGYGITVKYAQLTASLFRSAIERITSDPSFTERVKVISSQYRDQK 441
            |:|.:|.||||..|..|.|..|.|:|:...::||....:|::.:.::.|:.|.:..:||.::|:.
Mouse   389 PMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRP 453

  Fly   442 ETPLERAVYWVEHVTRHKGAKYLRSACQDLNFIQYHNLDVLATFFSVIGLTVIFV 496
            ..||:.||:|||:|.|||||.:||.|..||.:.|||:|||:. |...|.|||:|:
Mouse   454 IEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIG-FLLAIVLTVVFI 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302E1	NP_652625.2	egt	<114..464	CDD:223071	113/354 (32%)
Ugt1a1	NP_964007.2	egt	20..507	CDD:223071	151/505 (30%)
		UDPGT	30..526	CDD:278624	149/497 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840315
Domainoid	1	1.000	259	1.000	Domainoid score	I1975
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2975
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm42461
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.690