Protein Alignment Ugt302E1 and Ugt1a5

DIOPT Version :10

• Sequence 1: NP_652625.2
• Gene: Ugt302E1 / 53508
• FlyBaseID: FBgn0040257
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_964005.2
• Gene: Ugt1a5 / 394433
• MGIID: 3032634
• Length: 529
• Species: Mus musculus
• Alignment Length: 530
• Identity: 155/530 - (29%)
• Similarity: 249/530 - (46%)
• Gaps: 83/530 - (15%)

  Fly     9 LLLILALFGQSWGYSYLMISHTASKSHYAVCFALAKGLAAAGHEVTLVSP--------------- 58
            |||:.||   .|.....::......||:.....:.:.|.|.||:..:::|
Mouse    13 LLLLCAL---PWTEGEKVLVFPVGGSHWLSMRDVVRELHAQGHQTVVLAPEVNMRIKEEDFFTFK 74

  Fly    59 ---FP-QRKPIKNIIDVETPNIITVMGVYKARILENAK-----KPVLLRYPRISLMGLDITESLL 114
               .| .|:.::.:  :|...:....|.|..:|.:.::     ..|||:         ..|..|.
Mouse    75 VYAVPYTRQELEEM--MENLKVFFDTGNYMKKIFKTSEALRNMSTVLLK---------TCTNILH 128

  Fly   115 KEPKVQELLKQNRTFDGVI------CETFMNDAHYGFAEHFGAPLITLSSLGATGWTSDLVGTPS 173
            .|..:..|  .:.:||.|.      |...:       |::.|.|.:........|...:....||
Mouse   129 NESLLHHL--NSSSFDVVFTDPVFPCGALL-------AKYLGIPAVFFLRYIPCGIEYEATQCPS 184

  Fly   174 PPSYVPHSLLRFGDRMNFWERAQNLGFQIYEFAYENLINL--PRHEALYRKYFPNNKQDFYRMRK 236
            |.||:|:...|..|.|:|.:|.||:   :|....:.:.:|  ..:|:|..:.|          ::
Mouse   185 PSSYIPNLFTRLSDHMDFLQRVQNM---LYHLVLKYICHLLITPYESLASELF----------QR 236

  Fly   237 DTSLVLLNNHVSI---------SNPRPYSPNMIEVGGMHVNRKAPKPLPQNIRKFIE-EAEHGVI 291
            :.|.|.|.::.|:         ..|||..|||:.:||  :|....|||.|....::. ..|||::
Mouse   237 EVSSVELFSYASVWLFRGDFVLDYPRPIMPNMVFIGG--INCVTKKPLSQEFEAYVNASGEHGIV 299

  Fly   292 YFSLGSNLNSKDLPENKRKAIVETLRGLKYRVIWKYEEETFVDKPDNVLISNWLPQDDILAHEKV 356
            .|||||.::  ::||.|...|.|.|..:...|:|:|......:...|.::..||||:|:|.|.|.
Mouse   300 VFSLGSMVS--EIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKT 362

  Fly   357 IAFITHGGLLSTMESIYHGKPVVGIPFFGDQFMNMARAEQMGYGITVKYAQLTASLFRSAIERIT 421
            .|||||.|.....|.|.:|.|:|.:|.||||..|..|.|..|.|:|:...::||....:|::.:.
Mouse   363 RAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVI 427

  Fly   422 SDPSFTERVKVISSQYRDQKETPLERAVYWVEHVTRHKGAKYLRSACQDLNFIQYHNLDVLATFF 486
            ::.|:.|.:..:||.::|:...||:.||:|||:|.|||||.:||.|..||.:.|||:|||:. |.
Mouse   428 NNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIG-FL 491

  Fly   487 SVIGLTVIFV 496
            ..|.|||:|:
Mouse   492 LAIVLTVVFI 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302E1	NP_652625.2	Glycosyltransferase_GTB-type	<170..496	CDD:471961	120/337 (36%)
Ugt1a5	NP_964005.2	UDPGT	26..520	CDD:278624	149/514 (29%)