DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt302E1 and Ugt301D1

DIOPT Version :9

Sequence 1:	NP_652625.2	Gene:	Ugt302E1 / 53508	FlyBaseID:	FBgn0040257	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_001246079.1	Gene:	Ugt301D1 / 35105	FlyBaseID:	FBgn0032684	Length:	530	Species:	Drosophila melanogaster

Alignment Length:	539	Identity:	171/539 - (31%)
Similarity:	286/539 - (53%)	Gaps:	37/539 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRWLLNSWLLL-ILALFGQSWGYSYLMISHTASKSHYAVCFALAKGLAAAGHEVTLVSPFPQRKP 64
            ::|  ..|:|: ::.|.....|...|.:....:.||:.........|...||.||.|:..|.:.|
  Fly     5 LQW--KCWMLIFLIGLLEFGAGSRILFMGPFPAPSHWLWLEHFQNDLLRQGHHVTSVNNHPTKHP 67

  Fly    65 IKNIIDV------ETPNIITVMGVYKARILENAKKPVLLRYPRISL---MGLDITESLLKEPKVQ 120
            .:|:.::      :.|.......::..:.:.:        :..:.|   :||..||...|:|||:
  Fly    68 HENLTEIIISPSFDIPKHFPKENIFSMQFVSD--------FNNLELWWTIGLMTTEHAFKDPKVK 124

  Fly   121 ELLK-QNRTFDGVICETFMNDAHYGFAEHFGAPLITLSSLGATGWTSDLVGTPSPPSYVPHSLLR 184
            :|:: ::..:|.||.|.|.::|...|.:.|..|::|:.::|........:|..:|.|.:||.||.
  Fly   125 KLIESKDDHYDLVIIEQFFHEAFLMFGKRFNCPVVTIGTMGYADNIDHAMGILTPWSLIPHLLLS 189

  Fly   185 FGDRMNFWERAQNLGFQIYEFAYENLINLPRHEALYRKYFPNNKQ----DFYRMRKDTSLVLLNN 245
            ..|||.|.:||.|....:|:......:.||:.:.|..|||..:.:    :...:.::.||||:|.
  Fly   190 HTDRMTFGQRAYNAYLSLYDAVMRRWVYLPKMQKLAEKYFQGSIEGPLPNVLDLERNISLVLINA 254

  Fly   246 HVSISNPRPYSPNMIEVGGMHVNRKAPKPLPQNIRKFIEEAEHGVIYFSLGSNLNSKDLPENKRK 310
            |.||..|||..|.:|:|||.|:.:  ||.||.:::.|::.|.:||||||:||.:.|.|||:.|..
  Fly   255 HRSIDLPRPSMPGLIDVGGAHIQK--PKQLPTDLQNFLDNATYGVIYFSMGSYVKSTDLPQEKTA 317

  Fly   311 AIVETLRGLKYRVIWKYEEETFVDKPDNVLISNWLPQDDILAHEKVIAFITHGGLLSTMESIYHG 375
            .|::....||.:||||:|.::..|.|.||:|..|:||:|||||..|..||||||:..|.|.||.|
  Fly   318 LILKAFGQLKQQVIWKFENDSIGDLPSNVMIKKWMPQNDILAHPNVKLFITHGGIFGTQEGIYWG 382

  Fly   376 KPVVGIPFFGDQFMNMARAEQMGYGITVKYAQLTASLFRSAIERITSDPSFTERVKVISSQYRDQ 440
            .|::.:|.:|||..|..::.:.||..::.:::||.......||.:.:||.:......:|.::||.
  Fly   383 VPMLCVPLYGDQHRNTIKSVREGYARSLVFSKLTTDDLVRNIETLINDPQYKRSALEVSQRFRDN 447

  Fly   441 KETPLERAVYWVEHVTRHKGAKYLRSACQDLNFIQYHNLDVLATFFSVIGLTVIFVFLLVRF--- 502
            ...||:.|.:|:|::.||:||::|:|....:...||..||||       |..::..||.:..
  Fly   448 PIHPLDEATFWIEYIIRHRGARHLKSHGAFIPLHQYLLLDVL-------GCLLLGAFLAIWLPWR 505

  Fly   503 LVTIVNGFLYKPSSKLKIN 521
            ::..|:.:..|..|..|:|
  Fly   506 MIRRVHKWWLKGESSNKLN 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302E1	NP_652625.2	egt	<114..464	CDD:223071	132/354 (37%)
Ugt301D1	NP_001246079.1	egt	12..483	CDD:223071	155/480 (32%)
Ugt301D1	NP_001246079.1	UDPGT	37..483	CDD:278624	151/455 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	1	0.900	-	-		E33208_3BDT1
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm6444
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	9	8.860