Protein Alignment Ugt302E1 and Ugt2b37

DIOPT Version :10

• Sequence 1: NP_652625.2
• Gene: Ugt302E1 / 53508
• FlyBaseID: FBgn0040257
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_001007265.4
• Gene: Ugt2b37 / 29623
• RGDID: 3937
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 570
• Identity: 153/570 - (26%)
• Similarity: 258/570 - (45%)
• Gaps: 104/570 - (18%)

  Fly     8 WLLLILALFGQSWGYSYLMISHTASK--------SHYAVCFALAKGLAAAGHEVTLVSPF----- 59
            |:..:|.|     ..|:.:.|....|        ||:.....:...|...|||||::.|.
  Rat     5 WIFALLLL-----QISFCLRSAKCGKVLVWPMEFSHWMNIKTILDELVQRGHEVTVLKPSAYYVL 64

  Fly    60 -PQRKP--------------------IKNIIDVETPNIITVMGVYKARILENAKKPVLLRYPRIS 103
             |::.|                    || ::|..|..:.....:..:.:|:|........|
  Rat    65 DPKKSPDLKFETFPTSVSKDELEKYFIK-LVDAWTYELQRDTCLSFSPLLQNMMDEFSDYY---- 124

  Fly   104 LMGLDITESLLKEPKVQELLKQNRTFDGVICETFMNDAHYG--FAEHFGAPLITLSSLGATGWTS 166
               |.:.:..:...::...|:::: ||.::.:..   |..|  .||....|.  |.||.|
  Rat   125 ---LSVCKDAVSNKQLMAKLQESK-FDVLLSDPV---AACGELIAEVLHIPF--LYSLRA----- 175

  Fly   167 DLVGTPS------------PPSYVPHSLLRFGDRMNFWERAQNLGFQIYEFAYENLINLPRHEAL 219
                :|.            ||||||..|...|.:|.|.:|.:|:...:|...:.::.|....:..
  Rat   176 ----SPGHKIEKSSGRFILPPSYVPVILSGLGGQMTFIDRVKNMICMLYFDFWFHMFNAKNWDPF 236

  Fly   220 YRKYFPNNKQDFYRMRKDTSLV---------LLNNHVSISNPRPYSPNMIEVGGMHVNRKAPKPL 275
            |.:.          :.:.|:|.         |:.::..:..|.|..||:..:||:..  |..|||
  Rat   237 YTEI----------LGRPTTLAETMGKAEMWLIRSYWDLEFPHPTLPNVDYIGGLQC--KPAKPL 289

  Fly   276 PQNIRKFIEEA-EHGVIYFSLGSNLNSKDLPENKRKAIVETLRGLKYRVIWKYEEETFVDKPDNV 339
            |::|..|::.: ||||:.|||||.::|  :.|.|..|:...|..:..:|:||::.:.......|.
  Rat   290 PKDIEDFVQSSGEHGVVVFSLGSMVSS--MTEEKANAVAWALAQIPQKVLWKFDGKIPATLGPNT 352

  Fly   340 LISNWLPQDDILAHEKVIAFITHGGLLSTMESIYHGKPVVGIPFFGDQFMNMARAEQMGYGITVK 404
            .:..||||:|:|.|.|..||:||||.....|:||||.|::|||.||:|..|:|.....|..:|:.
  Rat   353 RVYKWLPQNDLLGHPKTKAFVTHGGANGVYEAIYHGIPMIGIPMFGEQHDNIAHMVAKGAAVTLN 417

  Fly   405 YAQLTASLFRSAIERITSDPSFTERVKVISSQYRDQKETPLERAVYWVEHVTRHKGAKYLRSACQ 469
            ...::.|...:|::.:.::|.:.:....:|:.:.||...||::|::|:|:|.|||.||:||....
  Rat   418 IRTMSKSDLFNALKEVINNPFYKKNAMWLSTIHHDQPMKPLDKAIFWIEYVMRHKRAKHLRPLGH 482

  Fly   470 DLNFIQYHNLDVLATFFSVIGLTVIFVFLLVRFLVTIVNGFLYKPSSKLK 519
            :|.:.|||:|||:.  |.:..|.||....:..||  .:..|..|...|:|
  Rat   483 NLPWYQYHSLDVIG--FLLACLAVIAALAVKCFL--FIYRFFAKKQKKMK 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302E1	NP_652625.2	Glycosyltransferase_GTB-type	<170..496	CDD:471961	110/347 (32%)
Ugt2b37	NP_001007265.4	UDPGT	24..527	CDD:278624	146/543 (27%)