Protein Alignment Ugt302E1 and Ugt2a3

DIOPT Version :10

• Sequence 1: NP_652625.2
• Gene: Ugt302E1 / 53508
• FlyBaseID: FBgn0040257
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_001129341.1
• Gene: Ugt2a3 / 289533
• RGDID: 1308444
• Length: 534
• Species: Rattus norvegicus
• Alignment Length: 538
• Identity: 173/538 - (32%)
• Similarity: 252/538 - (46%)
• Gaps: 76/538 - (14%)

  Fly     1 MRWLLNSWLLLILALFGQSWGYSYLMISHTASKSHYAVCFALAKGLAAAGHEVTLVSPFPQRKPI 65
            ::|.:   .:.:|.|.....|....::......||:.....:.:.|||.|||||::. :|
  Rat     4 VKWAV---AIFLLQLCWSGCGICSKVLVWPCDMSHWLNLKTILEELAARGHEVTVLK-YP----- 59

  Fly    66 KNIIDVE--TP-NIITVMGVYKARILENAKKPVLLR----YPRISLMGLDITESLLKEPKVQE-L 122
            ..|||..  || ....:..:|:..:.||....::..    .|.:||.....|        :|: .
  Rat    60 SIIIDQSKLTPLQFENIPVLYETEVAENHLNEIVNLAVNVIPNLSLWEAART--------LQDFF 116

  Fly   123 LKQNRTFDGVIC------ETFMN---DAHYGFAEHFGAPLITLSSLGATGWTSDLVGT------- 171
            |:....|:. :|      :|.||   ||.|...  ...|:|....|.|.......|.|
  Rat   117 LQLTGNFED-LCRSTLYNQTLMNKLRDAKYDVM--VLDPVIPCGELVAEVLQIPFVNTLRFSMGY 178

  Fly   172 ---------PSPPSYVPHSLLRFGDRMNFWERAQNL--------GFQIYEFAYENLINLPRHEAL 219
                     |.|.||||..:....|.|.|.||.:|:        ..|.|:||:        .:..
  Rat   179 SMEKYCGQLPVPLSYVPVVMGELTDHMTFTERVKNMMLSLFFEFWLQQYDFAF--------WDQF 235

  Fly   220 YRKYFPNNKQDFYRMRKDTSLVLLNNHVSISNPRPYSPNMIEVGGMHVNRKAPKPLPQNIRKFIE 284
            |.|.. .....|.:......:.|:..:..|..||||.||...|||:|.  |..||||:.:.:|::
  Rat   236 YSKTL-GRPTTFCKTVGKAEIWLIRTYWDIEFPRPYLPNFEFVGGLHC--KPAKPLPKELEEFVQ 297

  Fly   285 EA-EHGVIYFSLGSNLNSKDLPENKRKAIVETLRGLKYRVIWKYEEETFVDKPDNVLISNWLPQD 348
            .: ||||:.|||||.:  |:|.|.|...|...|..:..:|:|:|..:.......|..|.||:||:
  Rat   298 SSGEHGVVVFSLGSMI--KNLTEEKANLIASALAQIPQKVLWRYSGKKPATLGPNTRILNWIPQN 360

  Fly   349 DILAHEKVIAFITHGGLLSTMESIYHGKPVVGIPFFGDQFMNMARAEQMGYGITVKYAQLTASLF 413
            |:|.|.|..|||||||.....|:||||.|:||||.||||..|:|..|..|..:.|....:|::..
  Rat   361 DLLGHPKTRAFITHGGTNGIYEAIYHGVPMVGIPMFGDQPYNIAHMEAKGAAVKVAINTMTSADL 425

  Fly   414 RSAIERITSDPSFTERVKVISSQYRDQKETPLERAVYWVEHVTRHKGAKYLRSACQDLNFIQYHN 478
            .||:..:.::||:.|....:|..:.||...||:|||:|:|.|.||||||:||.|..||::.|||:
  Rat   426 LSALRAVINEPSYKENAMRLSRVHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHS 490

  Fly   479 LDVLATFFSVIGLTVIFV 496
            |||:. |..|..:|:.||
  Rat   491 LDVIG-FLLVCVVTLTFV 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302E1	NP_652625.2	Glycosyltransferase_GTB-type	<170..496	CDD:471961	129/350 (37%)
Ugt2a3	NP_001129341.1	UDPGT	25..519	CDD:278624	169/514 (33%)