DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt302E1 and ugt-3

DIOPT Version :9

Sequence 1:	NP_652625.2	Gene:	Ugt302E1 / 53508	FlyBaseID:	FBgn0040257	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_506203.2	Gene:	ugt-3 / 191174	WormBaseID:	WBGene00013903	Length:	529	Species:	Caenorhabditis elegans

Alignment Length:	550	Identity:	143/550 - (26%)
Similarity:	240/550 - (43%)	Gaps:	66/550 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LLILALFGQSWGYSYLMISHTASKSHYAVCFALAKGLAAAGHEVTLVSP-----FPQRKPIKNII 69
            ||:||.|..::|::||:||.....||......:|..||.|||.|||..|     :..:|.:||
Worm     4 LLLLAFFPVAFGFNYLIISPVFGYSHMKFMGRIADILADAGHNVTLFQPIIYDYYAHKKIVKN-- 66

  Fly    70 DVETPNIITV---------MGVYKARIL------ENAKKPVLLRYPRISLMGLDIT-ESLLKEPK 118
                |||..:         ....:|.:.      :.:|.|:         ....|| |.|.||.:
Worm    67 ----PNIEVINYEVDEEEKAAASEASVFKFFWKAKGSKNPI---------SSAKITSEKLYKEFE 118

  Fly   119 --VQELLKQNRTFDGVICETFMNDAHYGFAEHF-GAPL---------ITLSSLGATGWTSDLVGT 171
              .:::|........::.:.|  |:|...|..| |..|         |.|.|....|..|..||.
Worm   119 HICRKMLLDKELHRWILSKNF--DSHISEAFDFCGLYLGDFLKLKSPIPLYSGVRCGAASYAVGE 181

  Fly   172 PSPPSYVPHSLLRFGDRMNFWERAQN-LGFQIYEFAYENLINLPRHEALYRKYFPNNKQDFYRMR 235
            |.|.:|:|.....:|.:.:..:|..: ||...|.|.:..|.: .:::..|| ....|.:.:..:.
Worm   182 PIPLNYLPTEGSNYGKKSSAIDRLSDMLGLTGYHFQFGILFD-KQYDQAYR-LTGGNVRTWQEIL 244

  Fly   236 KDTSLVLLNNHVSISNPRPYSPNMIEVGGMHVNRKAPKPLPQNIRKFIEEAEHGVIYFSLGSNLN 300
            :.::..|.|::..:|...|....:|::||..:.......|.:...|.: ...:..|..|.|:.:.
Worm   245 QSSTFFLTNSNPYLSFSTPTISKVIQIGGFTIESFKTTTLDEEFNKIL-SLRNNTILVSFGTVIQ 308

  Fly   301 SKDLPENKRKAIVETLRGL-KYRVIWKYEEE--TFVDK-PDNVLISNWLPQDDILAHEKVIAFIT 361
            |.|:|::.:..::|..|.: ....||||||:  |..:| .:||::|.|:||..:||..::..|:|
Worm   309 SSDMPDDFKTGLIEAFRRMPDATFIWKYEEDDKTLKNKLSENVVLSKWIPQPALLADSRLDLFVT 373

  Fly   362 HGGLLSTMESIYHGKPVVGIPFFGDQFMNMARAEQMGYGITV-KYAQLTASLFRSAIERITSDPS 425
            ||||.||||..|.|...:.:|.|.||.:|.....:.|..|.. |:..:.:......|:.|.::..
Worm   374 HGGLGSTMEVGYAGVSSIMVPVFSDQGVNAEMLARHGGAIVYDKFDLVDSKKLMETIQMILNNSD 438

  Fly   426 FTERVKVISSQYRDQKETPLERAVYWVEHVTRHKGAKYLRSACQDLNFIQYHNLDVLATFFSVIG 490
            :.:..|.:|....:|...|.:..:...|...|......|.......|||:::.||.||.....|.
Worm   439 YRKNSKRLSDILHNQPMDPKQVLLNHCEFAARFAQVDNLEPYANKYNFIEFYCLDSLALVVCTIS 503

  Fly   491 LTVIFVFLLVRFLVTIVNGFLYKPSSKLKI 520
            :..:.:|.::.|:|..|       ..|||:
Worm   504 VVALVMFKILSFVVNSV-------IEKLKL 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302E1	NP_652625.2	egt	<114..464	CDD:223071	92/367 (25%)
ugt-3	NP_506203.2	egt	1..457	CDD:223071	124/472 (26%)
ugt-3	NP_506203.2	UDPGT	27..525	CDD:278624	131/524 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810