DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt302E1 and ugt-31

DIOPT Version :9

Sequence 1:	NP_652625.2	Gene:	Ugt302E1 / 53508	FlyBaseID:	FBgn0040257	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_001021756.1	Gene:	ugt-31 / 189771	WormBaseID:	WBGene00021464	Length:	521	Species:	Caenorhabditis elegans

Alignment Length:	548	Identity:	131/548 - (23%)
Similarity:	216/548 - (39%)	Gaps:	112/548 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 LMISHTASKSHYAVCFALAKGLAAAGHEVTL---VSPFPQRKPI-----KNIIDVETPNIITVMG 81
            |:.|.....||......:|..|..|||.||.   |:...:|..|     ||:|.|:.||.
Worm    20 LVYSPVFGGSHSKFMGNIADTLTEAGHNVTFLVSVADVTRRHEIGVKLTKNVIIVDKPNF----- 79

  Fly    82 VYKARILENAKKPVLLRYPRISLMGLDITESLLKEPKVQELLK-----QNRTFDGVICETFM--- 138
                     ::..|                    |..:.|:|:     |||..|...|..|.
Worm    80 ---------SQDDV--------------------EIDMDEVLRPLWTIQNRPSDFATCFEFFIQM 115

  Fly   139 --------------------NDAHYGFAEHFGAPLITLSSLG---ATGWTSDLV----------- 169
                                .:.|...||.     :::..||   |.|....::
Worm   116 MQTTCAEFTSNREIFKKLSKTEFHVAIAEP-----VSICGLGYFDALGIKKTILASSTTHYEGVV 175

  Fly   170 ---GTPSPPSYVPHSLLRFGDRMNFWERAQNLGFQIYEFAYENLI--NLPR----HEALYRKYFP 225
               |.|...||||.....|.::|:.::|..|       :|.|:::  ||.|    ..:.|||...
Worm   176 RNSGEPVDMSYVPVHGAYFDEKMDIFQRYTN-------WASEHVLAGNLERMFDQEMSEYRKNLV 233

  Fly   226 NNKQDFYRMRKDTSLVLLNNHVSISNPRPYSPNMIEVGGMHVNRKAPK--PLPQNIRKFIEEAEH 288
            .:...:..:....||:..|::..:..|||.....:.:||:.|:.:..|  .||:.|.|.:|:.|:
Worm   234 QSTGHWRDLIPSASLMFTNSNPYLDFPRPVLQKTVGIGGITVDMEQIKSEKLPEKINKLLEKREY 298

  Fly   289 GVIYFSLGSNLNSKDLPENKRKAIVETLRGL-KYRVIWKYEEE--TFVDKPDNVLISNWLPQDDI 350
            .:: .|.||.:.|..:||..|.:|:..:|.. ....|||||.:  .:.:..:||....|:||..:
Worm   299 NML-ISFGSMVKSSTMPEKWRNSILSAIRNFPNVTFIWKYESDDLRWAENVENVHFLKWIPQTAL 362

  Fly   351 LAHEKVIAFITHGGLLSTMESIYHGKPVVGIPFFGDQFMNMARAEQMGYGITV-KYAQLTASLFR 414
            |.:.:|.||:|||||.||.|..:.|||.:.:|.||||..|.....:.|..:.: |:....|.:..
Worm   363 LNNPRVSAFLTHGGLGSTNELAFIGKPSIIVPIFGDQGRNAPMLARHGGALVLQKFDLENAEVLI 427

  Fly   415 SAIERITSDPSFTERVKVISSQYRDQKETPLERAVYWVEHVTRHKGAKYLRSACQDLNFIQYHNL 479
            ..|.:|..|.|:.:..|.:::.......:|.|..|...|.|........:....:.||:.|....
Worm   428 DFIGKIVFDKSYAKNAKTLANLLNASPFSPKELVVKNTEFVGNFGPLTQMDPYIRKLNWFQRTFA 492

  Fly   480 DVLATFFSVIGLTVIFVFLLVRFLVTIV 507
            |:....|.|....::....::|.:..::
Worm   493 DIYLILFLVYASIIVIPIYVIRKVFRLI 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302E1	NP_652625.2	egt	<114..464	CDD:223071	103/406 (25%)
ugt-31	NP_001021756.1	UDPGT	28..518	CDD:278624	129/536 (24%)
ugt-31	NP_001021756.1	Glycosyltransferase_GTB_type	<248..472	CDD:299143	68/224 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810