DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt302E1 and ugt-36

DIOPT Version :9

Sequence 1:	NP_652625.2	Gene:	Ugt302E1 / 53508	FlyBaseID:	FBgn0040257	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_504820.2	Gene:	ugt-36 / 184266	WormBaseID:	WBGene00017315	Length:	533	Species:	Caenorhabditis elegans

Alignment Length:	558	Identity:	140/558 - (25%)
Similarity:	224/558 - (40%)	Gaps:	94/558 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LILALFGQSWGYSYLMISHTASKSHYAVCFALAKGLAAAGHEVTLVSPFPQR--------KPIKN 67
            |..||...|  |::|:.......||......:|..|..|||.||..:|...|        |.|.:
Worm    14 LFFALCSDS--YNFLVFCPLFGHSHTTFFAKIADTLTYAGHNVTFFTPTIVRKFSKIQYVKSITH 76

  Fly    68 IIDVETPNIITVMG-VYKARILENAKKPVLLRYPRISLMGLDITESLLKEPKVQELLKQNRTFDG 131
            ::.::..:.:..:| :::.:                     |:::...::..:.|:|....||:.
Worm    77 VLQLDPSDRLVKLGSMFEEK---------------------DVSKFWYRDSSLSEMLPMIDTFNN 120

  Fly   132 VICE---TFMNDAH-----------YGFAEHFGAP-------LITLSSLGATGWTSDL-----VG 170
            :..|   ....:.|           ....|||..|       |.....:.||....|.     :|
Worm   121 MFVEQAAVISRNLHVLDDLKEMNFDVMIFEHFVEPAYLVLDYLEIQKFIPATSLAFDYNMVKSIG 185

  Fly   171 TPSPPSYVPHSLLRFGDRMNFWERAQNLGFQIYEFAYENLINLPRHEALYRKYFP-----NNKQD 230
            .|...|.||.....:.|||:..:|..|   .|....::|||  |:::  ||.|.|     |.|.
Worm   186 EPLMLSTVPLPTSEYSDRMSLPQRLIN---AINPLIFDNLI--PKNK--YRSYRPPYAPINTKS- 242

  Fly   231 FYRMRKDTSLVLLNNHVSISNPRPYSPNMIEVGGMHVN-RKAPKPLPQNIRKFIEEAEHGVIYFS 294
               :....|.|..|::..|..||......::|||:.|: .|.......|....:.......:..|
Worm   243 ---IEPFCSAVFTNSNPYIDYPRATLEKNVQVGGISVDIDKLKSQKVSNEWDAVLNLRPKTVLVS 304

  Fly   295 LGSNLNSKDLPENKRKAIVETLRGLKY---RVIWKYE--EETFVDKPDNVLISNWLPQDDILAHE 354
            .||.:.|||:|.| .|..:.|:.| |:   ..|||||  :.:|.:..:|:..|||:||..:||..
Worm   305 FGSIMLSKDMPIN-NKITIATVLG-KFPDVTFIWKYETNDTSFANGTENIHFSNWVPQTALLADP 367

  Fly   355 KVIAFITHGGLLSTMESIYHGKPVVGIPFFGDQFMNMARAEQMGYGITV-KYAQLTASLFRSAIE 418
            ::.||.||.||.|..|..|.|||.:..|.|.||..|.....:....|.: ||..........|:.
Worm   368 RLSAFFTHAGLGSVNEVSYLGKPTIMCPIFADQMRNAKMLARHNGSIEISKYDLSNGDKIEEALS 432

  Fly   419 RITSDPSFTERVKVISSQYRDQKETPLERAVYWVEHVTRHKGAKYLRSACQDLNFIQYHNLDVLA 483
            :|..|.|:....:.::.|..:|...|.|..|...|...:......|....:.::||||..:|:.|
Worm   433 KILFDESYKTAAEKLAHQLANQPVKPKELLVRHAEFAAQFGHLPSLDPHSRQMSFIQYFLIDLTA 497

  Fly   484 TFFSVIGLTVIFVFLLVRFLVTIVNGFLYKPSSKLKIN 521
            ...|.:   ::|:|:|.:     :...:|   |||..|
Worm   498 IILSTV---ILFLFVLFK-----LGKLMY---SKLPFN 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302E1	NP_652625.2	egt	<114..464	CDD:223071	103/387 (27%)
ugt-36	NP_504820.2	Glycosyltransferase_GTB_type	6..507	CDD:299143	132/531 (25%)
ugt-36	NP_504820.2	YjiC	25..455	CDD:224732	114/463 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	193	1.000	Inparanoid score	I2536
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.860