DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt302E1 and ugt-15

DIOPT Version :9

Sequence 1:	NP_652625.2	Gene:	Ugt302E1 / 53508	FlyBaseID:	FBgn0040257	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_506211.1	Gene:	ugt-15 / 183462	WormBaseID:	WBGene00008097	Length:	534	Species:	Caenorhabditis elegans

Alignment Length:	558	Identity:	152/558 - (27%)
Similarity:	240/558 - (43%)	Gaps:	102/558 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LLILALFGQSWGYSYLMISHTASKSHYAVCFALAKGLAAAGHEVTLVSPFPQR--------KPIK 66
            ||.|.|......|..|:.:.....||......::..|..|||:||::.|....        |.:|
Worm     6 LLTLLLLELVCSYKVLVFNPAFGASHSNFLGKISDILIDAGHDVTMLIPVCMESKKDLVGSKKVK 70

  Fly    67 NIIDVETPNIITVMGVYKARILENAKKPVLLRYPRISLMGLDIT-----------------ESLL 114
            .||.::...        ::::::...|...:...:|..:..|||                 |::.
Worm    71 KIIRIDQEP--------RSKLMQEEAKTEEMIKKQIWKLDADITIFFSMIKNFSIASGYQCENIF 127

  Fly   115 KEPKVQELLKQNRTFD-GVICETFMNDAHYGFAEHFGAPLITLSSLGA-TGWTSDLV-------- 169
            |:..:.|.|: |..|| |:....|:          .|.||  |.|:|. |...:|.|
Worm   128 KQTAILEQLR-NEHFDLGITESLFI----------CGFPL--LDSIGVKTIINADSVLYLDVVKH 179

  Fly   170 --GTPSPPSYVPHSLLRFGDRMNFWERAQNLGFQIYEFAYENLINLPRH----EALYRKYFPNNK 228
              |.|:..||.|....:..|||:|.||.:||    :..|:....:..|.    ||:  |.:.|..
Worm   180 ALGEPASTSYYPGVYAKNIDRMSFRERVRNL----FGMAFSWYFSWTRFQGELEAI--KPYYNKS 238

  Fly   229 QDFYRMRKDTSLVLLNNHVSISNPRPYSPNMIEVGGMHVNR------KAPKPLPQ--NIRKFIEE 285
            ..:.......:...:|::..:..|.|..|..:.:|||.||.      |..|....  |:||
Worm   239 LTWEDHINGAAYYFINSNQYLDYPSPTLPKTVFIGGMQVNTNKHGKVKLEKEWDDLLNLRK---- 299

  Fly   286 AEHGVIYFSLGSNLNSKDLPENKRKAIVETLRGL-KYRVIWKYEEE--TFVDKPDNVLISNWLPQ 347
               ..:..|.|||..|.|:|:..:::.::....: :...|||||:|  |..|:..||.::.|:||
Worm   300 ---QNVLVSFGSNAFSCDMPDEFKESFLKVFASMPETTFIWKYEQENATLADQLSNVKLTTWMPQ 361

  Fly   348 DDILAHEKVIAFITHGGLLSTMESIYHGKPVVGIPFFGDQFMNMARAEQMGYGITVKYAQLTAS- 411
            :||||.|::..|:|||||.|:||..|.|||.|.||...||..|.....:.|..:.:....|..|
Worm   362 NDILADERLTLFVTHGGLGSSMELAYQGKPAVVIPLMADQPRNALMLTRHGGALQLDKTFLNNSE 426

  Fly   412 LFRSAIERITSDPSFTERVK----VISSQYRDQKETPLERAVYWVEHVTRHKGAKYLRSACQDLN 472
            ..|.||:.:..:||:.:..:    ::|||....|:..|:..    :...:|...|.|.|..:.||
Worm   427 KIREAIQTVMENPSYKKNAEKLANILSSQPHQPKDVVLKHC----DFAVKHGDLKTLNSEGRHLN 487

  Fly   473 FIQYHNLDV-------LATFFSVIGLTVIFVFLLVRFL 503
            ..||:::|:       |.|..|.|..|:||||..|.|:
Worm   488 VFQYYSIDIALAAGLFLVTIISFIIFTIIFVFKKVYFM 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302E1	NP_652625.2	egt	<114..464	CDD:223071	109/381 (29%)
ugt-15	NP_506211.1	UDPGT	19..506	CDD:278624	137/524 (26%)
ugt-15	NP_506211.1	Glycosyltransferase_GTB_type	<252..493	CDD:299143	79/251 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810