DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt302E1 and ugt-9

DIOPT Version :9

Sequence 1:	NP_652625.2	Gene:	Ugt302E1 / 53508	FlyBaseID:	FBgn0040257	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_504312.1	Gene:	ugt-9 / 178883	WormBaseID:	WBGene00020587	Length:	533	Species:	Caenorhabditis elegans

Alignment Length:	572	Identity:	146/572 - (25%)
Similarity:	238/572 - (41%)	Gaps:	127/572 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LLLILAL--------FGQSWGYSYLMISHTASKSHYAVCFALAKGLAAAGHEVTLVSPFPQRKPI 65
            :||:::|        :...:||           ||......||..:|..||.||:..||  ...:
Worm     9 ILLVISLVSCKNILVYNPIFGY-----------SHAKFVSQLANIIADHGHNVTVFQPF--HIAL 60

  Fly    66 KNIIDVETPNIITVMGVYKARILENAKK----------------PVLLRYPRISLMGLDI---TE 111
            ||...:.....|.::..|.....|..||                |||..:.....:|.:.   |.
Worm    61 KNTDGLIKNKNIEIINYYPDHYAELLKKKTPTFPDFWDSHLMNNPVLSSFLMPKALGGEFEQTTT 125

  Fly   112 SLLKEPKVQELLKQNRTFDGVICETFMNDAHYGFAEHFGAPLITLSSLGATGWTSDLVGTPSPPS 176
            .|.::.|:...|| ||.||.::.||| ..|.:..|:....|.|.|.|...........|.||...
Worm   126 QLFQDQKILNDLK-NRNFDVLLAETF-EIAGFYIADLLEIPSIPLMSAVRLPIIDSAFGQPSILG 188

  Fly   177 YVPHSLLRFGDRMNFWERAQNLGFQIYEFAYENLINLPRHEALYRKYFPN--------NKQDFYR 233
            |.|....:......|.:|..:                     |||.:|.|        .:.||.:
Worm   189 YFPQQYSKVAPEAGFLDRLND---------------------LYRIFFWNLTTQRLCQFQNDFIQ 232

  Fly   234 ------------MRKDTSLVLLNNHVSISNPRPYSPNMIEVGGMHVNRKAPK---PLPQNIRKFI 283
                        :.|::.:.:.|::..:....|.:..::.|||:.::.:..:   .|.:.....:
Worm   233 KAIGHPVPHWRDLVKESPIYITNSNSYLDFAVPTTATIVHVGGITIDLEKMRHVAALTEEYENIL 297

  Fly   284 EEAEHGVIYFSLGSNLNSKDLPENKRKAIVETLRGL-KYRVIWKYEEE--TFVDK-PDNVLISNW 344
            .|.| ..::.|.||.:.|.::|:|.:..|::..:.| ....|||||::  .|.:: |.||.:..|
Worm   298 AERE-STVFISFGSVIRSYEMPDNFKAGIIKMFKSLPDVTFIWKYEKDDVKFQNRLPKNVHLKKW 361

  Fly   345 LPQDDILAHEKVIAFITHGGLLSTMESIYHGKPVVGIPFFGDQFMN---MARAEQMGYGITVKY- 405
            :||..:||.::|..|:|||||.||||..|.|||.:.:|.||||..|   :||     :|..|.|
Worm   362 VPQPSLLADKRVKLFVTHGGLGSTMEVAYTGKPALMVPIFGDQPNNADMLAR-----HGGAVAYD 421

  Fly   406 -------AQLTASLFRSAIERITSDPSFTERVKVISSQYRDQK---ETPLERAVYWVEHVTRHKG 460
                   .:||.:: |..:.....:.:..|.:||:|.|..|.|   ...||.|:.:.:|
Worm   422 KFDLADGEKLTKTV-RDMVTNSKYEVNAQELLKVLSKQPIDPKLNLMKHLEFAMEFPKH------ 479

  Fly   461 AKYLRSACQDLN---FIQYHNLDVLA--TFFSVIGLTVIFVFL-LVRFLVTI 506
                ||....:|   .|.::.|||:.  |..|:.||.|||..| ::|.::::
Worm   480 ----RSQVPAINRTGLIAHYYLDVIGVLTLASIFGLFVIFKILNILRKMISL 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302E1	NP_652625.2	egt	<114..464	CDD:223071	101/390 (26%)
ugt-9	NP_504312.1	egt	20..462	CDD:223071	121/484 (25%)
ugt-9	NP_504312.1	UDPGT	30..532	CDD:278624	142/551 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810