DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt302E1 and ugt-11

DIOPT Version :9

Sequence 1:	NP_652625.2	Gene:	Ugt302E1 / 53508	FlyBaseID:	FBgn0040257	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_504311.1	Gene:	ugt-11 / 178882	WormBaseID:	WBGene00020593	Length:	533	Species:	Caenorhabditis elegans

Alignment Length:	577	Identity:	146/577 - (25%)
Similarity:	246/577 - (42%)	Gaps:	104/577 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRWLLNSWLLLILALFGQSWGYSYLMISHTASKSHYAVCFALAKGLAAAGHEVTLVSPFPQRKPI 65
            ||.|..|.|..:|.:   ::....|:.:.....||......||..:|..|.||||..||  ...:
Worm     1 MRLLTFSCLCFLLKV---NYAAKILIFNPIFGFSHVKFVSKLADIIADHGQEVTLFQPF--HLAL 60

  Fly    66 KNIIDVETPNIITVMGVY-------------------KARILENAKKPVLLRY--PRISLMGLDI 109
            ||:..:.....|.::..|                   .::::.|   |||:.:  |||  :|.:.
Worm    61 KNLDGIVKNKNIEIINYYPDHYDDLLKLETQTFPDFWDSQLMNN---PVLMAFMLPRI--LGGEF 120

  Fly   110 TESLLKEPKVQELLK--QNRTFDGVICETFMNDAHYGFAEHF-GAPLITLSSLGATGWTSDLVGT 171
            .::.::..|.:|:||  :::.||..|.|||.....|  ..|| |.|.|.:.|.......::..|.
Worm   121 KKTTIQLIKDKEILKKLKDKKFDVAISETFELTGMY--MSHFLGVPCIPILSAVRLDIFNEAFGQ 183

  Fly   172 PSPPSYVPHSLLRFGDRMNFWERAQNLGFQIYEFAYENLINLPRHEALYRKYFPNNKQDFYRMR- 235
            .|...|    |.:.|.::     |.:.||            |.|...:||.:|  :|..|..|.
Worm   184 SSAFGY----LTQQGSKL-----APDAGF------------LDRLNDVYRDFF--SKMAFRGMAQ 225

  Fly   236 ---------------------KDTSLVLLNNHVSISNPRPYSPNMIEVGGMHVNRKAPK---PLP 276
                                 |:..:.:.|::..:....|.:..::.:||:.:|.:...   .||
Worm   226 YQNDVIEKAAGHVVPYWKDLVKEAPVYMTNSNPYLDFAVPTTATIVHIGGITINLEKMNHVDALP 290

  Fly   277 QNIRKFIEEAEHGVIYFSLGSNLNSKDLPENKRKAIVETLRGLKYRV-IWKYE--EETFVDK-PD 337
            :.....::|.|..|: .|.||.:.|.::|||.:..:::....|...: |||||  :..|..| |.
Worm   291 EEYEIILKEKETTVL-ISFGSVIRSYEMPENFKAGLIKVFESLPDVIFIWKYEIDDLEFQKKLPK 354

  Fly   338 NVLISNWLPQDDILAHEKVIAFITHGGLLSTMESIYHGKPVVGIPFFGDQFMNMARAEQMGYGIT 402
            ||.:..|:||..:||.::|..|:|||||.||||..|.|||.:.:|.||||.||.....:.|..|.
Worm   355 NVHLKKWVPQPSLLADKRVKLFVTHGGLGSTMEVAYTGKPALMVPIFGDQPMNADMLARHGGAIA 419

  Fly   403 V-KYAQLTASLFRSAIERITSDPSFTERVKVISSQYRDQKETPLERAVYWVEHVTRHKGAKYLRS 466
            . |:..:........:..:.::|.:.::.|.:.....:|   |::..:..::|:........|||
Worm   420 YDKFDLVDGKKLTETVRDLVTNPKYEQKAKELLDVLTNQ---PIDPVMNLMKHLEFAIKFPNLRS 481

  Fly   467 ACQDLNF---IQYHNLDVLATFFSVIGLTVIFVFLLV-RFLVTIVNGFLYKPSSKLK 519
            ...::|.   |.::.|||:.....|..:|....|.:| |.|..|:       |.|:|
Worm   482 QIPEINQVGPIAHYYLDVIVFLIFVSIITAYISFQIVCRILSRIL-------SKKVK 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302E1	NP_652625.2	egt	<114..464	CDD:223071	97/382 (25%)
ugt-11	NP_504311.1	egt	<220..514	CDD:223071	76/297 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810