Protein Alignment Ugt302E1 and UGT3A1

DIOPT Version :9

• Sequence 1: NP_652625.2
• Gene: Ugt302E1 / 53508
• FlyBaseID: FBgn0040257
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_689617.3
• Gene: UGT3A1 / 133688
• HGNCID: 26625
• Length: 523
• Species: Homo sapiens
• Alignment Length: 546
• Identity: 153/546 - (28%)
• Similarity: 239/546 - (43%)
• Gaps: 96/546 - (17%)

  Fly     9 LLLILALFG---QSWGYSYLMISHTASKSHYAVCFALAKGLAAAGHEVTLV-------------- 56
            |||:..|..   .|.....|.|| |...|||.:...:::.|...||.||::
Human     7 LLLVAFLLSGVLLSEAAKILTIS-TLGGSHYLLLDRVSQILQEHGHNVTMLHQSGKFLIPDIKEE 70

  Fly    57 ----------SPFPQRKPIKNIID--VETPNIITVMGVYKARILENAKKPVLLRYPRISLMGLDI 109
                      ||...:|.||...|  :||             .|:..|:...|    :.||.:..
Human    71 EKSYQVIRWFSPEDHQKRIKKHFDSYIET-------------ALDGRKESEAL----VKLMEIFG 118

  Fly   110 TES--LLKEPKVQELLKQNRTFDGVICETFMNDAHYGFAEHFGAPLITLSSLGATGWTSDLVGTP 172
            |:.  ||....:.:.|| |..:|.|..|.| :...:..||....|.:.:  |..|..:.|. |.|
Human   119 TQCSYLLSRKDIMDSLK-NENYDLVFVEAF-DFCSFLIAEKLVKPFVAI--LPTTFGSLDF-GLP 178

  Fly   173 SPPSYVP--HSLLRFGDRMNFWERAQNLGFQIYEFA---------YENLINLPRHEALYRKYFPN 226
            ||.||||  .|||.  |.|:||.|.:|. ...:.|:         ::|.|         :::||.
Human   179 SPLSYVPVFPSLLT--DHMDFWGRVKNF-LMFFSFSRSQWDMQSTFDNTI---------KEHFPE 231

  Fly   227 NKQD-FYRMRKDTSLVLLNNHVSISNPRPYSPNMIEVGGMHVNRKAPKPLPQNIRKFIEE-AEHG 289
            ..:. ...:.....|..:|:..:....||..||.:.:||:  ..|..||:||::..||.. .:.|
Human   232 GSRPVLSHLLLKAELWFVNSDFAFDFARPLLPNTVYIGGL--MEKPIKPVPQDLDNFIANFGDAG 294

  Fly   290 VIYFSLGSNLN---SKDLPENKRKAIVETLRGLKYRVIWKYEEETF---VDKPDNVLISNWLPQD 348
            .:..:.||.||   |:::.:....|.....:|    |||..:...:   |....||.|.:||||.
Human   295 FVLVAFGSMLNTHQSQEVLKKMHNAFAHLPQG----VIWTCQSSHWPRDVHLATNVKIVDWLPQS 355

  Fly   349 DILAHEKVIAFITHGGLLSTMESIYHGKPVVGIPFFGDQFMNMARAEQMGYGITVKYAQLTASLF 413
            |:|||..:..|:||||..|.||:|.||.|:||:|..|||..||.|.....||::::..|:||...
Human   356 DLLAHPSIRLFVTHGGQNSVMEAIRHGVPMVGLPVNGDQHGNMVRVVAKNYGVSIRLNQVTADTL 420

  Fly   414 RSAIERITSDPSFTERVKVISSQYRDQKETPLERAVYWVEHVTRHKGAKYLRS-ACQDLNFIQYH 477
            ...::::..|..:...|...|.....|..:|.:|.|.|::|:.:..||.:|:. |.|.    .:|
Human   421 TLTMKQVIEDKRYKSAVVAASVILHSQPLSPAQRLVGWIDHILQTGGATHLKPYAFQQ----PWH 481

  Fly   478 NLDVLATFFSVIGLTVIFVFLLVRFL 503
            ...::..|..::|||:..::|..:.|
Human   482 EQYLIDVFVFLLGLTLGTMWLCGKLL 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302E1	NP_652625.2	egt	<114..464	CDD:223071	111/368 (30%)
UGT3A1	NP_689617.3	UDPGT	23..523	CDD:330975	148/530 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150072
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.740