DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt302E1 and ugt2b1

DIOPT Version :9

Sequence 1:	NP_652625.2	Gene:	Ugt302E1 / 53508	FlyBaseID:	FBgn0040257	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_001170809.1	Gene:	ugt2b1 / 100384895	ZFINID:	ZDB-GENE-100402-1	Length:	527	Species:	Danio rerio

Alignment Length:	538	Identity:	145/538 - (26%)
Similarity:	244/538 - (45%)	Gaps:	75/538 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LLILALF--GQSWGYSYLMISHTASKSHYAVCFALAKGLAAAGHEVTLVSP----FPQRKPIK-- 66
            |.:|.:|  ||.   ..:::.:|.. ||:.....:...|...||.||::.|    |.:.|...
Zfish     8 LSLLTVFSAGQC---GNILVWYTEG-SHWINLKIVLDTLLDRGHNVTVLMPDGALFMKAKESDRF 68

  Fly    67 ------------------------NIIDVETPNIITVMGVYKARILENAKKPVLLRYPRISLMGL 107
                                    ::.::|..|::.:...:...:.::..            |.|
Zfish    69 SYQHFSVSTSAQDMQDFLDEFLHFSVFELENSNLLQIQMKFFDLLSKHQD------------MSL 121

  Fly   108 DITESLLKEPKVQELLKQNRTFDGVICETFMNDAHYG----FAEHFGAPLITLSSLGATGWTSDL 168
            ...:.:||.|::.:.||:.: ||     ..::|..|.    .||....||:.............:
Zfish   122 SYCDGILKSPELMDKLKKGK-FD-----VLLSDPMYPCSDIVAEELNVPLVYTFRFSLAHTMERM 180

  Fly   169 VG-TPSPPSYVPHSLLRFGDRMNFWERAQNLGFQIYEFAYENLINLPRHEALYRKYFPNNKQDFY 232
            .| .|:|||:||.:..:..|:|:|.||..::.|.:....:..|| ..|.:..|.:|. .....:.
Zfish   181 CGQIPAPPSHVPGATSKLTDKMSFTERICSMLFYLSIDTFYRLI-WKRFDNYYTEYL-GRPTSYC 243

  Fly   233 RMRKDTSLVLLNNHVSISNPRPYSPNMIEVGGMHVNRKAPKPLPQNIRKFIEEA-EHGVIYFSLG 296
            .|.....:.|:..:.....|||:.||...:||:|..  ..||||:::.:|::.: :.|::.|:||
Zfish   244 EMMGRADIWLIRTYWDFEFPRPFVPNFKYIGGLHCT--PAKPLPKDMEEFVQSSGDDGIVVFTLG 306

  Fly   297 SNLNSKDLPENKRKAIVETLRGLKYRVIWKYEEETFVDKPD----NVLISNWLPQDDILAHEKVI 357
            |.::.  :|:.....|...|..:..:|:|:|..|    |||    |..|..|:||:|:|.|.|..
Zfish   307 SMIDK--VPKEMSNRIASALAQIPQKVLWRYGGE----KPDTLGENTRIYKWMPQNDLLGHPKTR 365

  Fly   358 AFITHGGLLSTMESIYHGKPVVGIPFFGDQFMNMARAEQMGYGITV-KYAQLTASLFRSAIERIT 421
            |||||||.....|:||||.|:||||.||||..||......|..:.| ....:........:..:.
Zfish   366 AFITHGGTNGIYEAIYHGVPMVGIPLFGDQPDNMVHMTTRGAAVVVDSIKSMQPQELVDKLNTVI 430

  Fly   422 SDPSFTERVKVISSQYRDQKETPLERAVYWVEHVTRHKGAKYLRSACQDLNFIQYHNLDVLATFF 486
            :|||:.|....:|..:.|:...||:.:|:|:|.|.|:||||:||....:|.:.|||.|||.|...
Zfish   431 NDPSYKENAMRLSRIHHDRPMKPLDESVFWIEFVMRNKGAKHLRVEAHNLTWYQYHCLDVFAFLT 495

  Fly   487 SVIGLTVIFVFLLVRFLV 504
            :|:.|.:.....:.:|.:
Zfish   496 TVLTLVLYICSKMAKFFI 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302E1	NP_652625.2	egt	<114..464	CDD:223071	112/360 (31%)
ugt2b1	NP_001170809.1	UDPGT	20..523	CDD:278624	140/523 (27%)
ugt2b1	NP_001170809.1	egt	<264..497	CDD:223071	88/240 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000