Protein Alignment Ugt35C1 and Ugt2a1

DIOPT Version :10

• Sequence 1: NP_001097744.1
• Gene: Ugt35C1 / 53507
• FlyBaseID: FBgn0040256
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: NP_444414.2
• Gene: Ugt2a1 / 94215
• MGIID: 2149905
• Length: 528
• Species: Mus musculus
• Alignment Length: 546
• Identity: 157/546 - (28%)
• Similarity: 272/546 - (49%)
• Gaps: 71/546 - (13%)

  Fly     9 IVFCALSAKPLESESAKILATLPFPGRSQYIFVESYLKALAAKGHQVTVINA------FKNKETP 67
            |:.|:|....|.......:...|..| |.::.|:..:..|..|.|.|||:.|      ..:..:|
Mouse     5 ILLCSLQISLLGMSLGGNVLIWPMEG-SHWLNVKIIIDELLRKEHNVTVLVASGALFITPSSISP 68

  Fly    68 NMRF-----------IEALKAHEFADEMMSLL-NVP---LLWQQLNAMDYILNKF-------IDV 110
            ::.|           ||::    ..|.:::.| |.|   .:|.....|..::.:|       .|.
Mouse    69 SLTFEIYPVPFGKEKIESV----IKDFVLTWLENRPSPSTIWTFYKEMAKVIEEFHLVSRGICDG 129

  Fly   111 TMEDEGVQRLLNSGETFDLVLAEMLHMEPMY----AFAQHFNATLVGFSSFGTDRTIDEAAGNIS 171
            .:::|.:...|.. |.|:::|:     :|::    ..|.......:....|....|:::..|.:.
Mouse   130 VLKNEKLMSKLQK-EKFEVLLS-----DPVFPCGDIVALKLGIPFIYSLRFSPASTVEKHCGKVP 188

  Fly   172 -PISYNPLVTSPRTDRMTFLERLENHYEVIVEDIHRHFVHLPHMRNVYKK---YFPNA---KKTL 229
             |.||.|.:.|..||:|:|.:|:.|.....::|.        ....::|:   |:..|   ..||
Mouse   189 FPPSYVPAILSELTDQMSFTDRVRNFISYRMQDY--------MFETLWKQWDSYYTKALGRPTTL 245

  Fly   230 EEVMDSFSLILLGQHFSLSYPRPYLPNMIEVGGMHISHKP-KPLPEDIKQFIEGS-PHGVIYFSM 292
            .|.|....:.|:..::...:|||||||...|||:|.  || ||||:::::|::.| .||::.||:
Mouse   246 CETMGKAEIWLMRTYWDFEFPRPYLPNFEFVGGLHC--KPAKPLPKEMEEFVQTSGEHGIVVFSL 308

  Fly   293 GSNVKSKDLPQETRDTLLKTFAKLKQRVLWKFEDDDMPGKPANVLIKKWYPQPDILAHPNVKLFI 357
            ||.|  |:|..|..:.:....|::.|:|||:::........:|..:..|.||.|:|.||..:.||
Mouse   309 GSMV--KNLTDEKANLIASALAQIPQKVLWRYKGKIPDTLGSNTRLFDWIPQNDLLGHPKTRAFI 371

  Fly   358 SHGGLLSSTESVYFGKPILGLPCFYDQHMNVQRAQRVGFGLGLDLNNLKQEDLEKAIQTLLTDPS 422
            :|||.....|::|.|.|::|:|.|.||..|:...:..|..:.:::|.:...||..|::|::.:||
Mouse   372 THGGTNGIYEAIYHGIPMVGVPMFADQPDNIAHMKAKGAAVEVNMNTMTSSDLLNALRTVINEPS 436

  Fly   423 YAKASLAISERYRDQPQSAVDRAVWWTEYVIRHNGAPHLRATSRDLNFIQLNSLDTLAVILAVPL 487
            |.:.::.:|..:.|||...:||||:|.|:|:||.||.|||..:.||::.|.:|||.:..:||. :
Mouse   437 YKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLAC-V 500

  Fly   488 LLALLIVTLSCKLL------GGKKQK 507
            ..|:|:|...|..:      .|||:|
Mouse   501 ASAILLVAKCCLFIFQKVGKTGKKKK 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35C1	NP_001097744.1	Glycosyltransferase_GTB-type	45..477	CDD:471961	137/472 (29%)
Ugt2a1	NP_444414.2	UDPGT	21..516	CDD:278624	149/518 (29%)