Protein Alignment Ugt35C1 and ugt2a6

DIOPT Version :10

• Sequence 1: NP_001097744.1
• Gene: Ugt35C1 / 53507
• FlyBaseID: FBgn0040256
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: NP_001138283.1
• Gene: ugt2a6 / 797211
• ZFINID: ZDB-GENE-081104-3
• Length: 529
• Species: Danio rerio
• Alignment Length: 547
• Identity: 154/547 - (28%)
• Similarity: 266/547 - (48%)
• Gaps: 61/547 - (11%)

  Fly     6 VIAIVFCALSAKPLESESAKILATLPFPGR-SQYIFVESYLKALAAKGHQVTVINAFKNKETPNM 69
            ::.::.|.:..    ..|.::|.   .||. |.:..:...::||..|.|.|||:....:...|:.
Zfish     7 LVCLLLCGVDV----GWSGRVLV---MPGEYSHWHNMRPVIEALVDKNHSVTVLVGSSSPTVPHT 64

  Fly    70 RFIEALKAHEFADEMMSLLNVPLLWQQLNAMDYILNKFI---DVTME------------DEGVQR 119
            : .|..:.|.|...|...: |..||  ::..:..:|:.|   :.|:|            :|.|:.
Zfish    65 Q-KERFEYHVFKVNMEKEV-VDYLW--IHFHELWMNETISTYEKTLEVWQLMSLFRAHSEELVKG 125

  Fly   120 LLNSG-------ETFDLVLAEMLHMEPMYAFAQHFN-----ATLVGFSSFGTDRTIDEAAGNIS- 171
            |.:.|       ..:|::.:: |.|......||..|     :..:.|:|     .::...|.:.
Zfish   126 LFDVGLLKTLRDSNYDVLFSD-LTMPFSDLMAQKLNIPHVLSMRISFAS-----ALERLCGQMPV 184

  Fly   172 PISYNPLVTSP--RTDRMTFLERLENHYEVIVEDIHRHFVHLP---HMRNVYKKYFPNAKKTLEE 231
            |.||.|...:.  .||||:|.||:||   :::...|.....|.   ...::|.: ......|:.|
Zfish   185 PQSYVPAAVAQGHLTDRMSFTERVEN---MLLYITHTAMFQLTTKFTFDHIYAE-ISGEPTTMCE 245

  Fly   232 VMDSFSLILLGQHFSLSYPRPYLPNMIEVGGMHISHKP-KPLPEDIKQFIEGS-PHGVIYFSMGS 294
            .:....:.|:..::...||||:.||...|||:..  || |||.:::::|::.| .||::.||:||
Zfish   246 TIGKTDIWLIRTYWDFEYPRPFPPNFKFVGGLQC--KPAKPLAKELEEFVQSSGDHGIVVFSLGS 308

  Fly   295 NVKSKDLPQETRDTLLKTFAKLKQRVLWKFEDDDMPGKPANVLIKKWYPQPDILAHPNVKLFISH 359
            .:  |:|..:..:|:.....::.|:|:|::..........|..|..|.||.|:|.||..|.||:|
Zfish   309 MI--KNLTVQKANTIAAALGQISQKVVWRYSGKTPETLAPNTKIYDWIPQNDLLGHPKTKAFITH 371

  Fly   360 GGLLSSTESVYFGKPILGLPCFYDQHMNVQRAQRVGFGLGLDLNNLKQEDLEKAIQTLLTDPSYA 424
            ||.....|::|.|.|::|||.|.||..|:...:..|..:.||...|:.:||..|::|:|.:|||.
Zfish   372 GGTNGLYEAIYHGVPMVGLPLFGDQPDNLMHLKSKGAAVVLDFFTLESKDLVDALKTVLNNPSYK 436

  Fly   425 KASLAISERYRDQPQSAVDRAVWWTEYVIRHNGAPHLRATSRDLNFIQLNSLDTLAVILAVPLLL 489
            ::.:.:|..:.|||...:|:||:|.|:|:|:.||.|||..:.:|::.|.:.||..|.:|::..|:
Zfish   437 ESIMRLSRIHHDQPMKPLDQAVYWIEFVMRNKGAKHLRVQAHELSWYQYHCLDVAAFLLSITALI 501

  Fly   490 ALLIVTLSCKLLGGKKQKCLHADKLKK 516
            ..|.|...|.|.....:|.....|.||
Zfish   502 TFLWVKACCFLFRRCVRKTRPERKSKK 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35C1	NP_001097744.1	Glycosyltransferase_GTB-type	45..477	CDD:471961	135/466 (29%)
ugt2a6	NP_001138283.1	UDPGT	21..519	CDD:278624	148/518 (29%)