Protein Alignment Ugt35C1 and ugt2a4

DIOPT Version :10

• Sequence 1: NP_001097744.1
• Gene: Ugt35C1 / 53507
• FlyBaseID: FBgn0040256
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: NP_001170804.2
• Gene: ugt2a4 / 791613
• ZFINID: ZDB-GENE-080721-23
• Length: 533
• Species: Danio rerio
• Alignment Length: 538
• Identity: 161/538 - (29%)
• Similarity: 269/538 - (50%)
• Gaps: 52/538 - (9%)

  Fly     4 LTVIAIVFCALSAKPLESESAKILATLPFPGR-SQYIFVESYLKALAAKGHQVTVI--------- 58
            :|..|::.|.|........|.::|.   .||. |.:..:.:.::||..:.|.|||:
Zfish     1 MTSGALLVCLLLCGVDVGWSGRVLV---MPGEYSHWHNMRAIIEALVDRNHSVTVLVSSSSPTVP 62

  Fly    59 ---------NAFK-NKETPNMRFIEALKAHEFADEMMSLLNVP-LLWQQLNAMDYILNKFIDVTM 112
                     :.|| |.:....:.|.:...|.:..|..|.|... |:|:.::....:........:
Zfish    63 HTQKARFDYHVFKVNMDKEEAKVIWSDFTHLWMKETDSKLERGFLIWRVMSNFRRLAADVCRSLL 127

  Fly   113 EDEGVQRLLNSGETFDLVLAEMLHMEPMY----AFAQHFNATLVGFSSFGTDRTIDEAAGNI-SP 172
            :::.:.::|  ||:.    .::|..:||.    ..||..|...|.........|.:...|.: :|
Zfish   128 QNDDLLQML--GESH----YDVLFSDPMMPCSDLMAQTLNIPQVISLRLTFAYTFERMCGQMPAP 186

  Fly   173 ISYNPLV--TSPRTDRMTFLERLENHYEVIVEDIHRHFVHLPHMRNVYKKYFPNAKK--TLEEVM 233
            .||.|.|  |...||||:|:||:||   :::..||.....|..|..|.:.|.....|  |:.|.|
Zfish   187 PSYVPAVALTDHLTDRMSFMERVEN---MLLYFIHTTVFRLNTMLTVDRLYTEIRGKPTTMCETM 248

  Fly   234 DSFSLILLGQHFSLSYPRPYLPNMIEVGGMHISHKP-KPLPEDIKQFIEGS-PHGVIYFSMGSNV 296
            ....:.|:..::...||||:.||...|||:|.  || |||.:::::|::.| .|||:.||:||.:
Zfish   249 GKADIWLIRTYWDFEYPRPFPPNFKFVGGLHC--KPAKPLSKEMEEFVQSSGDHGVVVFSLGSMI 311

  Fly   297 KSKDLPQETRDTLLKTFAKLKQRVLWKFEDDDMPGKPANVLIKKWYPQPDILAHPNVKLFISHGG 361
              |:|..|..:|:.....::.|:|:|::..........|..|..|.||.|:|.||..|.||:|||
Zfish   312 --KNLTSERANTIAAALGQIPQKVVWRYSGKTPETLAPNTKIYDWIPQNDLLGHPKTKAFITHGG 374

  Fly   362 LLSSTESVYFGKPILGLPCFYDQHMNVQRAQRVGFGLGLDLNNLKQEDLEKAIQTLLTDPSYAKA 426
            .....|::|.|.|::|||.|.||..|:...:..|..:.||:|.|:.:||..|::|:|.:|||.::
Zfish   375 TNGLYEAIYHGVPMVGLPLFADQPDNLLHMKTKGAAVVLDINTLESKDLVDALKTVLNNPSYKES 439

  Fly   427 SLAISERYRDQPQSAVDRAVWWTEYVIRHNGAPHLRATSRDLNFIQLNSLDTLAVILAVPLLLAL 491
            .:.:|..:.|||...:|:||:|.|:|:|:.||.|||..:.:|::.|.:.||..|.:|::..|:..
Zfish   440 IMRLSRIHHDQPMKPLDQAVYWIEFVMRNKGAKHLRVQAHELSWYQYHCLDVAAFLLSIAALITF 504

  Fly   492 LIVTLSCKLLGGKKQKCL 509
            |.|...|.|.    ::|:
Zfish   505 LWVKACCFLF----RRCV 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35C1	NP_001097744.1	Glycosyltransferase_GTB-type	45..477	CDD:471961	142/462 (31%)
ugt2a4	NP_001170804.2	UDPGT	21..520	CDD:278624	156/518 (30%)