Protein Alignment Ugt35C1 and UGT2B10

DIOPT Version :10

• Sequence 1: NP_001097744.1
• Gene: Ugt35C1 / 53507
• FlyBaseID: FBgn0040256
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: NP_001066.1
• Gene: UGT2B10 / 7365
• HGNCID: 12544
• Length: 528
• Species: Homo sapiens
• Alignment Length: 507
• Identity: 158/507 - (31%)
• Similarity: 265/507 - (52%)
• Gaps: 48/507 - (9%)

  Fly    36 SQYIFVESYLKALAAKGHQVTVINA-----FKNKETPNMR---FIEALKAHEFADEMMSLLN--- 89
            |.::.:::.||.|..:||:|||:.:     |...::..::   :..:|...||.:.:|.|:.
Human    33 SLWMNMKTILKELVQRGHEVTVLASSASILFDPNDSSTLKLEVYPTSLTKTEFENIIMQLVKRLS 97

  Fly    90 --------VP------LLWQQLNAMDYILNKFI-DVTMEDEGVQRLLNSGETFDLVLAEMLHMEP 139
                    :|      :||    |::.|:..|. ||....:.:::|..|  .||:|.|: .::..
Human    98 EIQKDTFWLPFSQEQEILW----AINDIIRNFCKDVVSNKKLMKKLQES--RFDIVFAD-AYLPC 155

  Fly   140 MYAFAQHFNATLVGFSSFGTDRTIDEAAGN-ISPISYNPLVTSPRTDRMTFLERLENHYEVIVED 203
            ....|:.||...|...||....:.:..:|. |.|.||.|:|.|..:|:|||:||::|...|:..|
Human   156 GELLAELFNIPFVYSHSFSPGYSFERHSGGFIFPPSYVPVVMSKLSDQMTFMERVKNMLYVLYFD 220

  Fly   204 IHRHFVHLPHMRNVYKKYFPNAKKTLEEVMDSFSLILLGQHFSLSYPRPYLPNMIEVGGMHISHK 268
            ......::......|.:.. ....||.|.|....:.|:...::..:|.|:|||:..|||:|.  |
Human   221 FWFQIFNMKKWDQFYSEVL-GRPTTLSETMRKADIWLMRNSWNFKFPHPFLPNVDFVGGLHC--K 282

  Fly   269 P-KPLPEDIKQFIEGS-PHGVIYFSMGSNVKSKDLPQETRDTLLKTFAKLKQRVLWKFEDDDMPG 331
            | ||||:::::|::.| .:||:.||:||.|  .::.:|..:.:....||:.|:|||:|:.:....
Human   283 PAKPLPKEMEEFVQSSGENGVVVFSLGSMV--SNMTEERANVIATALAKIPQKVLWRFDGNKPDA 345

  Fly   332 KPANVLIKKWYPQPDILAHPNVKLFISHGGLLSSTESVYFGKPILGLPCFYDQHMNVQRAQRVGF 396
            ...|..:.||.||.|:|.||..:.||:|||.....|::|.|.|::|:|.|:||..|:...:..|.
Human   346 LGLNTRLYKWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFFDQPDNIAHMKAKGA 410

  Fly   397 GLGLDLNNLKQEDLEKAIQTLLTDPSYAKASLAISERYRDQPQSAVDRAVWWTEYVIRHNGAPHL 461
            .:.:|.|.:...||..|::|::.||||.:..:.:|....|||...:||||:|.|:|:||.||.||
Human   411 AVRVDFNTMSSTDLLNALKTVINDPSYKENIMKLSRIQHDQPVKPLDRAVFWIEFVMRHKGAKHL 475

  Fly   462 RATSRDLNFIQLNSLDTLAVILAVPLLLALLIVTLSCKLL------GGKKQK 507
            |..:.:|.:.|.:|||.:..:||. :...|.|:|..|...      .|||.|
Human   476 RVAAHNLTWFQYHSLDVIGFLLAC-VATVLFIITKCCLFCFWKFARKGKKGK 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35C1	NP_001097744.1	Glycosyltransferase_GTB-type	45..477	CDD:471961	145/460 (32%)
UGT2B10	NP_001066.1	UDPGT	23..524	CDD:278624	155/503 (31%)