Protein Alignment Ugt35C1 and Ugt2a3

DIOPT Version :10

• Sequence 1: NP_001097744.1
• Gene: Ugt35C1 / 53507
• FlyBaseID: FBgn0040256
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: NP_082370.2
• Gene: Ugt2a3 / 72094
• MGIID: 1919344
• Length: 534
• Species: Mus musculus
• Alignment Length: 536
• Identity: 153/536 - (28%)
• Similarity: 265/536 - (49%)
• Gaps: 100/536 - (18%)

  Fly    36 SQYIFVESYLKALAAKGHQVTVIN--------------AFKNKETPNMRFIEAL--KAHEFADEM 84
            |.::.:::.|:.|.|:||:|||:.              .|:|  .|.:..||..  :.:|.|:..
Mouse    34 SHWLNLKTILEELGARGHEVTVLKYPSIIIDQSKRIPLHFEN--IPLLYEIETAENRLNEIANLA 96

  Fly    85 MSLLNVPLLWQQLNAM-DYILNKFIDVTMEDEGVQRLLNSGETF---------DLV--------- 130
            ::::....||:....: |:    |:.||.:.|.:.|.:...:.|         |:|
Mouse    97 VNVIPNLSLWEAAKTLQDF----FLQVTGDFESICRSVLYNQKFMDKLRDAQYDVVVIDPVVPCG 157

  Fly   131 --LAEMLHMEPMYAFAQHFNATLVGFSSFGTDRTIDEAAGNIS-PISYNPLVTSPRTDRMTFLER 192
              :||:|.:..:|..            .|.....:::..|.:. |:||.|:|.|..||.|||.||
Mouse   158 ELVAEVLQIPFVYTL------------RFSMGYYMEKHCGQLPIPLSYVPVVMSELTDNMTFTER 210

  Fly   193 LENH-----YEVIVEDIHRHFVHLPHMRNVYKKYFPNA---KKTLEEVMDSFSLILLGQHFSLSY 249
            ::|.     :|..::.....|         :.:::...   ..|..:.:....:.|:..::.:.:
Mouse   211 VKNMMFSLLFEYWLQQYDFAF---------WDQFYSETLGRPTTFCKTVGKADIWLIRTYWDVEF 266

  Fly   250 PRPYLPNMIEVGGMHISHKP-KPLPEDIKQFIEGS-PHGVIYFSMGSNVKSKDLPQETRDTLLKT 312
            |||||||...|||:|.  || ||||:::::|::.| .|||:.||:||.|  |:|.:|..:.:...
Mouse   267 PRPYLPNFEFVGGLHC--KPAKPLPKEMEEFVQSSGEHGVVVFSLGSMV--KNLTEEKANLIASV 327

  Fly   313 FAKLKQRVLWKFEDDDMPGKPA----NVLIKKWYPQPDILAHPNVKLFISHGGLLSSTESVYFGK 373
            .|::.|:|||::...    |||    |..:..|.||.|:|.||..|.||:|||.....|::|.|.
Mouse   328 LAQIPQKVLWRYSGK----KPATLGSNTRLFNWIPQNDLLGHPKTKAFITHGGTNGIYEAIYHGV 388

  Fly   374 PILGLPCFYDQHMNVQRAQRVGFGLGLDLNNLKQEDLEKAIQTLLTDPSYAKASLAISERYRDQP 438
            |::|:|...||..|:...:..|..|.:.::.:...||..|::.::.:|||.:.::.:|..:.|||
Mouse   389 PMVGVPMLGDQPHNIAHMEAKGAALKVSISTMTSTDLLSAVRAVINEPSYKENAMRLSRIHHDQP 453

  Fly   439 QSAVDRAVWWTEYVIRHNGAPHLRATSRDLNFIQLNSLDTLAVILAVPLLLALLIVTLSC----- 498
            ...:||||:|.|:|:||.||.|||..:.||::.|.:|||.:..:|...:.|. .|:|..|
Mouse   454 VKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLLCVVTLT-FIITKFCLFVCQ 517

  Fly   499 -------KLLGGKKQK 507
                   |.:|.:|:|
Mouse   518 KLYMKESKKMGNRKKK 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35C1	NP_001097744.1	Glycosyltransferase_GTB-type	45..477	CDD:471961	141/483 (29%)
Ugt2a3	NP_082370.2	UDPGT	25..526	CDD:278624	149/527 (28%)