Protein Alignment Ugt35C1 and Ugt2b1

DIOPT Version :10

• Sequence 1: NP_001097744.1
• Gene: Ugt35C1 / 53507
• FlyBaseID: FBgn0040256
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: NP_690024.1
• Gene: Ugt2b1 / 71773
• MGIID: 1919023
• Length: 529
• Species: Mus musculus
• Alignment Length: 509
• Identity: 156/509 - (30%)
• Similarity: 260/509 - (51%)
• Gaps: 51/509 - (10%)

  Fly    36 SQYIFVESYLKALAAKGHQVTVINAF-------KNKETPNMRFIEALKAH---EFADE------M 84
            |.:|.::..|..|..:||.|||:.:.       .|:.:.|.....|..:.   |:|.|      .
Mouse    34 SHWINMKIILDELVQRGHDVTVLISSASILIGPSNESSINFEIYSAPLSKDDLEYAFEKWVGNWT 98

  Fly    85 MSLLNVPLLWQQLNAMDYILNKFIDV-------TMEDEGVQRLLNSGETFDLVLAEMLHMEPMYA 142
            ..|..:| .|...:.:..|.:::.|:       .:.::.:.:.| .|..||:|||:.|  .|...
Mouse    99 YELKKLP-FWTSYSKLQKISSEYSDMIESFCKAVVWNKSLMKKL-QGSKFDVVLADAL--VPCGE 159

  Fly   143 FAQHFNATLVGFS-SFGTDRTIDEAAGNIS-PISYNPLVTSPRTDRMTFLERLENHYEVIVEDIH 205
            .......|.:.:| .|......::.:|.:. |.||.|:|.|..:|.|||.||::|..:|::.|
Mouse   160 LLSELLKTPLVYSLRFCPGYKCEKYSGGLPLPPSYVPVVLSELSDHMTFAERVKNMLQVLLFD-- 222

  Fly   206 RHFVHLPHMRNVYKKYFPNA---KKTLEEVMDSFSLILLGQHFSLSYPRPYLPNMIEVGGMHISH 267
              |.........:.:::.:.   ..||.|:|....:.|:...:.|.:|.|:|||...|||:|.
Mouse   223 --FWFQTFNEKSWNQFYSDVLGRPTTLTEMMGKADIWLVRTFWDLKFPHPFLPNFDFVGGLHC-- 283

  Fly   268 KP-KPLPEDIKQFIEGS-PHGVIYFSMGSNVKSKDLPQETRDTLLKTFAKLKQRVLWKFEDDDMP 330
            || ||||:::::|::.| .|||:.||:||.|  |::.:|..:.:....|::.|:|||:|:.....
Mouse   284 KPAKPLPKEMEEFVQSSGEHGVVVFSLGSMV--KNIKEEKANVVASALAQIPQKVLWRFDGKKPD 346

  Fly   331 GKPANVLIKKWYPQPDILAHPNVKLFISHGGLLSSTESVYFGKPILGLPCFYDQHMNVQRAQRVG 395
            ...:|..:.||.||.|:|.||..|.||:|||.....|::|.|.||:|:|.|.||..|:......|
Mouse   347 TLGSNTRLYKWIPQNDLLGHPKTKAFIAHGGTNGIYEAIYHGIPIVGIPLFGDQPDNINHIVAKG 411

  Fly   396 FGLGLDLNNLKQEDLEKAIQTLLTDPSYAKASLAISERYRDQPQSAVDRAVWWTEYVIRHNGAPH 460
            ..:.:|.:.:...||..|::|::.||||.:.::.:|..:.|||...:||||:|.|||:|:.||.|
Mouse   412 AAVRVDFDTMSTTDLLTALKTVINDPSYKENAMRLSRIHHDQPMKPLDRAVFWIEYVMRNKGAKH 476

  Fly   461 LRATSRDLNFIQLNSLDTLAVILAVPLLLALLIVTLSCKLL-------GGKKQK 507
            ||....||.:.|.:|||.:..:|.  .::|::.:...|.|.       .|||:|
Mouse   477 LRPALHDLTWFQYHSLDVIGFLLV--CVVAVVFIIAKCCLFCCHKTANMGKKKK 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35C1	NP_001097744.1	Glycosyltransferase_GTB-type	45..477	CDD:471961	144/461 (31%)
Ugt2b1	NP_690024.1	UDPGT	24..527	CDD:278624	154/506 (30%)