Protein Alignment Ugt35C1 and Ugt1a8

DIOPT Version :10

• Sequence 1: NP_001097744.1
• Gene: Ugt35C1 / 53507
• FlyBaseID: FBgn0040256
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: NP_001365304.1
• Gene: Ugt1a8 / 613123
• MGIID: 3576090
• Length: 530
• Species: Mus musculus
• Alignment Length: 565
• Identity: 155/565 - (27%)
• Similarity: 261/565 - (46%)
• Gaps: 108/565 - (19%)

  Fly    12 CALSAKPLESESAKILATLPFPGRSQYIFVESYLKALAAKGHQVTVI------------------ 58
            |.|.|..| :::.::| .:|..| |.:..::..::.|:.:||:|.|:
Mouse    15 CLLLAFGL-AQAGRLL-VVPMDG-SHWFSMKMIVEKLSHRGHEVVVVIPEVSWHLGKSQNFTVKT 76

  Fly    59 --------------NAFKNKETPNMR-------------FIEALKAHEFADEMMSLLNVPLLWQQ 96
                          |.|.:|:..|..             |.:.|.:|     ..||.|...|
Mouse    77 YSVSYTLEDLSHHFNFFAHKQWENREVGMFSLLKHSGKGFFQVLFSH-----CRSLFNDKKL--- 133

  Fly    97 LNAMDYILNKFIDVTMEDEGVQRLLNSGETFDLVLAEMLHMEPMYAFAQHFNATLVGFSSFGTDR 161
               ::|:..:..|....|           .||:.         ....|::|:...|.||......
Mouse   134 ---VEYLKQRSFDAVFLD-----------PFDVC---------GLTIAKYFSLPSVVFSGGIFCH 175

  Fly   162 TIDEAAGNISPISYNPLVTSPRTDRMTFLERLENHYEVIVEDIHRHFVHLPHMRNVYKKYFPNAK 226
            .:||.|...||.||.|.:.|...|.|||.||:.|::..:.|   |.|  .|:.   :|.....|.
Mouse   176 YLDEGAQCPSPPSYVPRILSKFADTMTFKERVWNYFSYMKE---RAF--CPYF---FKTAIEIAS 232

  Fly   227 K------TLEEVMDSFSLILLGQHFSLSYPRPYLPNMIEVGGMHISHKPKPLPEDIKQFIEGS-P 284
            :      |:.::..|.|:.:....|.|.:|||.:|||:.:||:: .|..|||.::.:.::..| .
Mouse   233 EVLQTPVTMTDLFSSVSIWMFRTDFVLEFPRPVMPNMVYIGGIN-CHPGKPLSKEFEAYVNASGE 296

  Fly   285 HGVIYFSMGSNVKSKDLPQETRDTLLKTFAKLKQRVLWKFEDDDMPGKPANVLIKKWYPQPDILA 349
            ||::.||:||.|  .::|::....:.:...::.|.|||::..........|.::.||.||.|:|.
Mouse   297 HGIVVFSLGSMV--SEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLG 359

  Fly   350 HPNVKLFISHGGLLSSTESVYFGKPILGLPCFYDQHMNVQRAQRVGFGLGLDLNNLKQEDLEKAI 414
            ||..:.||:|.|.....|.:..|.|::.:|.|.||..|.:|.:..|.|:.|::..:..:|||.|:
Mouse   360 HPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENAL 424

  Fly   415 QTLLTDPSYAKASLAISERYRDQPQSAVDRAVWWTEYVIRHNGAPHLRATSRDLNFIQLNSLDTL 479
            :|::.:.||.:..:.:|..::|:|...:|.||:|.|||:||.||||||..:.||.:.|.:|||.:
Mouse   425 KTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVI 489

  Fly   480 AVILAVPLLLALLIVTLSC------KLLGGK-KQKCLHADKLKKH 517
            ..:||:  :|.::.:...|      |..||| :.|..|  |.|.|
Mouse   490 GFLLAI--VLTVVFIVFKCCAYGCRKCFGGKGRVKKSH--KSKTH 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35C1	NP_001097744.1	Glycosyltransferase_GTB-type	45..477	CDD:471961	132/483 (27%)
Ugt1a8	NP_001365304.1	UDPGT	26..521	CDD:278624	146/540 (27%)