Protein Alignment Ugt35C1 and Ugt1a5

DIOPT Version :10

• Sequence 1: NP_001097744.1
• Gene: Ugt35C1 / 53507
• FlyBaseID: FBgn0040256
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: NP_964005.2
• Gene: Ugt1a5 / 394433
• MGIID: 3032634
• Length: 529
• Species: Mus musculus
• Alignment Length: 550
• Identity: 160/550 - (29%)
• Similarity: 270/550 - (49%)
• Gaps: 75/550 - (13%)

  Fly     9 IVFCALSAKPLESESAKILATLPFP-GRSQYIFVESYLKALAAKGHQVTVINAFKNKETP--NMR 70
            ::.|||.    .:|..|:|.   || |.|.::.:...::.|.|:|||..|:       .|  |||
Mouse    14 LLLCALP----WTEGEKVLV---FPVGGSHWLSMRDVVRELHAQGHQTVVL-------APEVNMR 64

  Fly    71 FIEALKAHEF--------------ADEMMSLLNVPL-----------LWQQLNAMDYILNKFIDV 110
                :|..:|              .:|||..|.|..           ..:.|..|..:|.|....
Mouse    65 ----IKEEDFFTFKVYAVPYTRQELEEMMENLKVFFDTGNYMKKIFKTSEALRNMSTVLLKTCTN 125

  Fly   111 TMEDEGVQRLLNSGETFDLVLAEMLHMEPMY----AFAQHFNATLVGFSSFGTDRTIDEAAGNIS 171
            .:.:|.:...||| .:||:|..     :|::    ..|::.....|.|..:.......||....|
Mouse   126 ILHNESLLHHLNS-SSFDVVFT-----DPVFPCGALLAKYLGIPAVFFLRYIPCGIEYEATQCPS 184

  Fly   172 PISYNPLVTSPRTDRMTFLERLENH-YEVIVEDIHRHFVHLPHMRNVYKKYFPNAKKTLEEVMDS 235
            |.||.|.:.:..:|.|.||:|::|. |.::::.| .|.:..|: .::..:.|.....:: |:...
Mouse   185 PSSYIPNLFTRLSDHMDFLQRVQNMLYHLVLKYI-CHLLITPY-ESLASELFQREVSSV-ELFSY 246

  Fly   236 FSLILLGQHFSLSYPRPYLPNMIEVGGMHISHKPKPLPEDIKQFIEGS-PHGVIYFSMGSNVKSK 299
            .|:.|....|.|.||||.:|||:.:||::...| |||.::.:.::..| .||::.||:||.|  .
Mouse   247 ASVWLFRGDFVLDYPRPIMPNMVFIGGINCVTK-KPLSQEFEAYVNASGEHGIVVFSLGSMV--S 308

  Fly   300 DLPQETRDTLLKTFAKLKQRVLWKFEDDDMPGKPANVLIKKWYPQPDILAHPNVKLFISHGGLLS 364
            ::|::....:.:...::.|.|||::..........|.::.||.||.|:|.||..:.||:|.|...
Mouse   309 EIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHG 373

  Fly   365 STESVYFGKPILGLPCFYDQHMNVQRAQRVGFGLGLDLNNLKQEDLEKAIQTLLTDPSYAKASLA 429
            ..|.:..|.|::.:|.|.||..|.:|.:..|.|:.|::..:..:|||.|::|::.:.||.:..:.
Mouse   374 IYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMR 438

  Fly   430 ISERYRDQPQSAVDRAVWWTEYVIRHNGAPHLRATSRDLNFIQLNSLDTLAVILAVPLLLALLIV 494
            :|..::|:|...:|.||:|.|||:||.||||||..:.||.:.|.:|||.:..:||:  :|.::.:
Mouse   439 LSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAI--VLTVVFI 501

  Fly   495 TLSC------KLLGGK-KQKCLHADKLKKH 517
            ...|      |..||| :.|..|  |.|.|
Mouse   502 VFKCCAYGCRKCFGGKGRVKKSH--KSKTH 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35C1	NP_001097744.1	Glycosyltransferase_GTB-type	45..477	CDD:471961	135/464 (29%)
Ugt1a5	NP_964005.2	UDPGT	26..520	CDD:278624	151/521 (29%)