Protein Alignment Ugt35C1 and Ugt1a10

DIOPT Version :10

• Sequence 1: NP_001097744.1
• Gene: Ugt35C1 / 53507
• FlyBaseID: FBgn0040256
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: NP_964003.2
• Gene: Ugt1a10 / 394430
• MGIID: 3580642
• Length: 530
• Species: Mus musculus
• Alignment Length: 570
• Identity: 164/570 - (28%)
• Similarity: 269/570 - (47%)
• Gaps: 104/570 - (18%)

  Fly     5 TVIAIVFCALSAKPLESESAKILATLPFPGRSQYIFVESYLKALAAKGHQVTVI----------- 58
            |.:.:..|.|.|..|  ..|..|..:|..| |.:..::..::.|..:||:|.|:
Mouse     8 TSLPLCVCLLLASGL--VQAGRLLVVPMDG-SHWFDMQMVVEKLIQRGHEVVVVIPEVSWRLGKS 69

  Fly    59 ------------------NAFK-----NKETP--NMRFIEALKAHEFADEMMSLLNVPLLWQQLN 98
                              ..||     ..:||  ::|......|..|.:.|.|  :...|:....
Mouse    70 LNCTVKTYSVSHTLEDLDREFKYFTYTQWKTPEQSIRSFMTGSARGFFELMFS--HSRGLFNDKK 132

  Fly    99 AMDYILNKFIDVTMEDEGVQRLLNSGETFD---LVLAEMLHMEPMYAFAQHFNATLVGFSSFGTD 160
            .::|:..:..|....|           .||   |::|:.|.: |...||:      :.|..:
Mouse   133 LVEYLKQRSFDAVFLD-----------PFDVCGLIVAKYLSL-PSVIFAR------LSFCYY--- 176

  Fly   161 RTIDEAAGNISPISYNPLVTSPRTDRMTFLERLENHYEVIVEDIHRHFVHLPHMRNVYKKYFPNA 225
              ::|.|...|.:||.|.:.|..||.|||.||:.||| :.:||    :|..|:       :|..|
Mouse   177 --LEEGAQCPSLLSYVPRLFSKYTDTMTFKERVWNHY-MYIED----YVFCPY-------FFKTA 227

  Fly   226 KKTLEEVM-------DSFSLI---LLGQHFSLSYPRPYLPNMIEVGGMHISHKPKPLPEDIKQFI 280
            .:...||:       |.||.:   ||...|.|.:|||.:|||:.||||:.. :.|||.::.:.::
Mouse   228 VEIASEVLQTPVTMTDLFSPVSIWLLRTDFVLEFPRPVMPNMVFVGGMNCL-QGKPLSKEFEAYV 291

  Fly   281 EGS-PHGVIYFSMGSNVKSKDLPQETRDTLLKTFAKLKQRVLWKFEDDDMPGKPANVLIKKWYPQ 344
            ..| .||::.||:||.|  .::|::....:.:...::.|.|||::..........|.::.||.||
Mouse   292 NASGEHGIVVFSLGSMV--SEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQ 354

  Fly   345 PDILAHPNVKLFISHGGLLSSTESVYFGKPILGLPCFYDQHMNVQRAQRVGFGLGLDLNNLKQED 409
            .|:|.||..:.||:|.|.....|.:..|.|::.:|.|.||..|.:|.:..|.|:.|::..:..:|
Mouse   355 NDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADD 419

  Fly   410 LEKAIQTLLTDPSYAKASLAISERYRDQPQSAVDRAVWWTEYVIRHNGAPHLRATSRDLNFIQLN 474
            ||.|::|::.:.||.:..:.:|..::|:|...:|.||:|.|||:||.||||||..:.||.:.|.:
Mouse   420 LENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYH 484

  Fly   475 SLDTLAVILAVPLLLALLIVTLSC------KLLGGK-KQKCLHADKLKKH 517
            |||.:..:||:  :|.::.:...|      |..||| :.|..|  |.|.|
Mouse   485 SLDVIGFLLAI--VLTVVFIVFKCCAYGCRKCFGGKGRVKKSH--KSKTH 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35C1	NP_001097744.1	Glycosyltransferase_GTB-type	45..477	CDD:471961	139/481 (29%)
Ugt1a10	NP_964003.2	UDPGT	26..521	CDD:278624	153/537 (28%)