Protein Alignment Ugt35C1 and Ugt3a1

DIOPT Version :10

• Sequence 1: NP_001097744.1
• Gene: Ugt35C1 / 53507
• FlyBaseID: FBgn0040256
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: NP_659094.1
• Gene: Ugt3a1 / 223337
• MGIID: 2145969
• Length: 523
• Species: Mus musculus
• Alignment Length: 557
• Identity: 144/557 - (25%)
• Similarity: 243/557 - (43%)
• Gaps: 117/557 - (21%)

  Fly    22 ESAKILATLPFPGRSQYIFVESYLKALAAKGHQVTV-------INAFKNKETPNMRFIE------ 73
            |:|||| |:.....|.||.:....:.|...||.||.       |..|: ||.|:.:.|.
Mouse    21 EAAKIL-TISTLSASHYIVISRVSQVLHEGGHNVTKLLYESANIPDFR-KEKPSYQVINWRPPED 83

  Fly    74 -------------------------ALKAHEFADEMMSLLNVPLLWQQLNAMDYILNKFIDVTME 113
                                     .||.|::..::.|     .|..:.:.||::.|:..|:.
Mouse    84 QEKKFADLRHRLTEEITYGRSKHHTLLKIHQYFGDLCS-----QLLSRKDIMDFLKNENFDLV-- 141

  Fly   114 DEGVQRLLNSGETFDLVLAEMLHMEPMYAFAQHFNATL---VGFSSFGTDRTIDEAAGNISPISY 175
                  ||:|.:...|::.|.|        .:.|.:.|   ..:..||...         :|:||
Mouse   142 ------LLDSMDLCSLLIVEKL--------GKRFVSFLPFQFSYMDFGLPS---------APLSY 183

  Fly   176 NPLVTSPRTDRMTFLERLEN----------HYEVIVE---DIHRHFVHLPHMRNVYKKYFPNAKK 227
            .|:..|..||:|.|..|::|          ..|::.:   .|..|||.             .::.
Mouse   184 APVYGSGLTDQMDFWGRVKNFLMFLDFSMKQREILSQYDSTIQEHFVE-------------GSQP 235

  Fly   228 TLEEVMDSFSLILLGQHFSLSYPRPYLPNMIEVGGMHISHKP-KPLPEDIKQFI-EGSPHGVIYF 290
            .|.:::....|..:...|:|.:.||..||.:.|||  :..|| :|:|:|::.|| :....|.:..
Mouse   236 VLSDLLLKAELWFVNSDFALDFARPLFPNTVYVGG--LLDKPVQPIPQDLENFISQFGDSGFVLV 298

  Fly   291 SMG---SNVKSKDLPQETRDTLLKTFAKLKQRVLWKFEDDDMP---GKPANVLIKKWYPQPDILA 349
            ::|   |.::||::.:|    :...||.|.|.|||..:....|   ....||.|..|.||.|:||
Mouse   299 ALGSIVSMIQSKEIIKE----MNSAFAHLPQGVLWTCKTSHWPKDVSLAPNVKIMDWLPQTDLLA 359

  Fly   350 HPNVKLFISHGGLLSSTESVYFGKPILGLPCFYDQHMNVQRAQRVGFGLGLDLNNLKQEDLEKAI 414
            ||:::||::|||:.|..|:|:.|.|::|:|.|:||..|:.|.:....|:.:.|..||.|.....:
Mouse   360 HPSIRLFVTHGGMNSVMEAVHHGVPMVGIPFFFDQPENMVRVEAKNLGVSIQLQTLKAESFALTM 424

  Fly   415 QTLLTDPSYAKASLAISERYRDQPQSAVDRAVWWTEYVIRHNGAPHLRATSRDLNFIQLNSLDTL 479
            :.::.|..|..|::|........|.:...|.:.|.:::::..||.||:..:....:.:...||..
Mouse   425 KKIIEDKRYKSAAMASKIIRHSHPLTPAQRLLGWIDHILQTGGAAHLKPYAFQQPWHEQYMLDVF 489

  Fly   480 AVILAVPLLLALLIVTLSCKLLGGKKQKCLHADKLKK 516
            ..:|.  |:|..|  .||.|:|....:....|.|:|:
Mouse   490 LFLLG--LMLGTL--WLSVKVLVAVTRYLSIATKVKE 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35C1	NP_001097744.1	Glycosyltransferase_GTB-type	45..477	CDD:471961	122/493 (25%)
Ugt3a1	NP_659094.1	Glycosyltransferase_GTB-type	23..488	CDD:471961	131/515 (25%)