Protein Alignment Ugt35C1 and Ugt1a2

DIOPT Version :10

• Sequence 1: NP_001097744.1
• Gene: Ugt35C1 / 53507
• FlyBaseID: FBgn0040256
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: NP_038729.1
• Gene: Ugt1a2 / 22236
• MGIID: 3576049
• Length: 533
• Species: Mus musculus
• Alignment Length: 575
• Identity: 162/575 - (28%)
• Similarity: 272/575 - (47%)
• Gaps: 108/575 - (18%)

  Fly     1 MRLLTVIAIVFCALSAKPLESESAKILATLPFPGRSQYIFVESYLKALAAKGHQVTVI------- 58
            :|.::.:.::.|||.    .:|.||:| .||..| ||::.:...::.|.|:|||..|:
Mouse     9 LRGISGLLLLLCALP----WAEGAKVL-VLPMEG-SQWLSMRDVVRELHARGHQTVVLASEVTVH 67

  Fly    59 ------------------------------NAFKNKETPNMRFIEALKAHEFAD----EMMSLLN 89
                                          ..||.:......|........|.|    ..::||:
Mouse    68 IKGEDFFTLKTYAFPYTKEEYQQEILSDIEKTFKTQHFVKAFFETTASIRNFFDLYSNSCIALLH 132

  Fly    90 VPLLWQQLNAMDYILNKFIDVTMEDEGVQRLLNSGETFDLVLAEMLHMEPMYAFAQHFNATLVGF 154
            ..:|.||||      :.|.||.:.|.    :...|    .|||:.|.:..::         ::..
Mouse   133 NKMLIQQLN------SSFFDVILTDP----IFPCG----AVLAKYLQIPAVF---------ILRS 174

  Fly   155 SSFGTDRTIDEAAGNISPISYNPLVTSPRTDRMTFLERLENH-YEVIVEDIHRHFVHLPH----- 213
            .|.|.:.   ||....:|.||.|.:.:..:|.|.||:|::|. |.::::.|.|..: .|:
Mouse   175 LSCGIEY---EATQCPNPSSYIPNLLTRLSDHMDFLQRVQNMLYYLVLKYICRLSI-TPYESLAS 235

  Fly   214 ---MRNVYKKYFPNAKKTLEEVMDSFSLILLGQHFSLSYPRPYLPNMIEVGGMHISHKPKPLPED 275
               .|.|          :|.||:...|:.|....|.|.||||.:|||:.:||::...| |||.::
Mouse   236 ELLQREV----------SLVEVLSHASVWLFRGDFVLDYPRPIMPNMVFIGGINCVTK-KPLSQE 289

  Fly   276 IKQFIEGS-PHGVIYFSMGSNVKSKDLPQETRDTLLKTFAKLKQRVLWKFEDDDMPGKPANVLIK 339
            .:.::..| .||::.||:||.|  .::|::....:.:...::.|.|||::..........|.::.
Mouse   290 FEAYVNASGEHGIVVFSLGSMV--SEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILV 352

  Fly   340 KWYPQPDILAHPNVKLFISHGGLLSSTESVYFGKPILGLPCFYDQHMNVQRAQRVGFGLGLDLNN 404
            ||.||.|:|.||..:.||:|.|.....|.:..|.|::.:|.|.||..|.:|.:..|.|:.|::..
Mouse   353 KWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLE 417

  Fly   405 LKQEDLEKAIQTLLTDPSYAKASLAISERYRDQPQSAVDRAVWWTEYVIRHNGAPHLRATSRDLN 469
            :..:|||.|::|::.:.||.:..:.:|..::|:|...:|.||:|.|||:||.||||||..:.||.
Mouse   418 MTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLT 482

  Fly   470 FIQLNSLDTLAVILAVPLLLALLIVTLSC------KLLGGK-KQKCLHADKLKKH 517
            :.|.:|||.:..:||:  :|.::.:...|      |..||| :.|..|  |.|.|
Mouse   483 WYQYHSLDVIGFLLAI--VLTVVFIVFKCCAYGCRKCFGGKGRVKKSH--KSKTH 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35C1	NP_001097744.1	Glycosyltransferase_GTB-type	45..477	CDD:471961	134/482 (28%)
Ugt1a2	NP_038729.1	UDPGT	28..524	CDD:278624	152/539 (28%)