Protein Alignment Ugt35C1 and Ugt2b37

DIOPT Version :10

• Sequence 1: NP_001097744.1
• Gene: Ugt35C1 / 53507
• FlyBaseID: FBgn0040256
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: NP_444445.2
• Gene: Ugt2b37 / 112417
• MGIID: 2148239
• Length: 530
• Species: Mus musculus
• Alignment Length: 544
• Identity: 163/544 - (29%)
• Similarity: 277/544 - (50%)
• Gaps: 85/544 - (15%)

  Fly     4 LTVIAIVFCALSAKPLESESAKILA-TLPFPGRSQYIFVESYLKALAAKGHQVTVIN-----AFK 62
            |.::.|..|..|.|     ..|:|. .:.|   |.::.::..|..|..:||:|||:.     ...
Mouse     9 LLLLQISCCFRSVK-----CGKVLVWPMEF---SHWMNIKIILDELVQRGHEVTVLRPSAYYVLD 65

  Fly    63 NKETPNMRFIEALKAHEFADEM----MSLLNV--------------PLLWQQLNAMD-YILNKFI 108
            .|::|.::| |........|::    :.||||              ||:....:.:. |.|:...
Mouse    66 PKKSPGLKF-ETFPTSVTKDDLENFFIQLLNVWTYELSRDTCLSYSPLMQNMFDELSGYYLSLCK 129

  Fly   109 DVTMEDEGVQRLLNSGETFDLVL-----------AEMLHMEPMYAFAQHFNATLVGFSSFGTDRT 162
            ||....:.:.:|..|  .||::|           ||:||:..:|:.            .|.....
Mouse   130 DVVSNRQLMTKLQES--KFDVLLSDPVAFGGELIAELLHIPFLYSL------------RFTAGYR 180

  Fly   163 IDEAAGN-ISPISYNPLVTSPRTDRMTFLERLENHYEVIVEDIHRHFVHLPHMR---NVYKKYFP 223
            |::::|. :.|.||.|::.|....:|||:||::|...::..|.   :..:|:.:   :.|.:|.
Mouse   181 IEKSSGRFLLPPSYVPVILSGLGGQMTFIERVKNMICMLYFDF---WFQMPNDKKWDSFYTEYL- 241

  Fly   224 NAKKTLEEVMDSFSLILLGQHFSLSYPRPYLPNMIEVGGMHISHKP-KPLPEDIKQFIEGS-PHG 286
            ....||.|.|....:.|:..::.|.:|.|.|||:..|||:|.  || ||||:|::::::.| .||
Mouse   242 GRPTTLAETMGQAEMWLIRSNWDLEFPHPTLPNVDYVGGLHC--KPAKPLPKDMEEYVQSSGDHG 304

  Fly   287 VIYFSMGSNVKSKDLPQETRDTLLKTFAKLKQRVLWKFEDDDMPGK-PA----NVLIKKWYPQPD 346
            |:.||:||.|  .::.:|..:.:....|::.|:|||||:     || ||    |..:.||.||.|
Mouse   305 VVVFSLGSMV--SNITEEKVNAIAWALAQIPQKVLWKFD-----GKTPATLGHNTRVYKWLPQND 362

  Fly   347 ILAHPNVKLFISHGGLLSSTESVYFGKPILGLPCFYDQHMNVQRAQRVGFGLGLDLNNLKQEDLE 411
            :|.||..|.||:|||..|..|::|.|.|::|:|.|.:||.|:......|..:.|::..:.:.|:.
Mouse   363 LLGHPKTKAFITHGGANSVYEAIYHGIPMIGIPLFGEQHDNIAHMVAKGAAVTLNIRTMSRSDVL 427

  Fly   412 KAIQTLLTDPSYAKASLAISERYRDQPQSAVDRAVWWTEYVIRHNGAPHLRATSRDLNFIQLNSL 476
            .|::.::.:|.|.|.::.:|..:.|||...:||||:|.|:|:||..|.|||....:|.:.|.:||
Mouse   428 NALEEVIENPFYKKNAMWLSTIHHDQPMKPLDRAVFWVEFVMRHKNAKHLRPLGHNLTWYQYHSL 492

  Fly   477 DTLAVILAVPLLLALLIVTLSCKL 500
            |.:..:||  .:.|.:::|:.|.|
Mouse   493 DVIGFLLA--CVAATVVLTVKCLL 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35C1	NP_001097744.1	Glycosyltransferase_GTB-type	45..477	CDD:471961	146/477 (31%)
Ugt2b37	NP_444445.2	UDPGT	24..527	CDD:278624	158/524 (30%)