Protein Alignment Ugt35E2 and Ugt1a6a

DIOPT Version :10

• Sequence 1: NP_652623.2
• Gene: Ugt35E2 / 53506
• FlyBaseID: FBgn0040255
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_659545.2
• Gene: Ugt1a6a / 94284
• MGIID: 2137698
• Length: 531
• Species: Mus musculus
• Alignment Length: 569
• Identity: 159/569 - (27%)
• Similarity: 262/569 - (46%)
• Gaps: 108/569 - (18%)

  Fly     6 LVLRLIVLVVALLPVLLEGARILGVFPIPSHSHYYHALPYLKKLASLGHEITSVSP--------- 61
            |||...||...||.|..:|:..|.:..|..|            |:..||:|..:.|
Mouse    18 LVLWASVLGDKLLVVPQDGSHWLSMKEIVEH------------LSERGHDIMVLVPEVNLLLGES 70

  Fly    62 -----------FPLKE------PVANIHDIPVPELFDNIEEIVGNLTNRKGTWNEFEYINQYTLG 109
                       :.|:|      ...|.|.:|...|...:.|...|:.
Mouse    71 KYYRRKIFSVTYSLEELQTRFRTFGNNHFLPGASLMGPLREYRNNMI------------------ 117

  Fly   110 LVEKVLENDGVRREILQPESLQFDLIIVDLWR---LDALYG---------LAAYFDAPIIGIASY 162
            :|:....|         .:||..|...:...|   .|||:.         ||.|.:.|.:.:..
Mouse   118 VVDMFFSN---------CQSLLKDSATLSFLRENKFDALFTDPAMPCGVILAEYLNLPSVYLFR- 172

  Fly   163 GTDWKIDELVG-NVSPLAYLQSPSF--NWFDLDTYGGRLGHFVDQSMAWINWHWRHEERHEAVYR 224
            |....::.::| :.||::|:  |.|  .:.|..|:..||.:|:...:        ....:..:|.
Mouse   173 GFPCSLEHMLGQSPSPVSYV--PRFYTKFSDHMTFPQRLANFIVNIL--------ENYLYYCLYS 227

  Fly   225 KYFPKIAD--KR--SLSEITRNFALILVNQHFTMAPPRPYVPNIIEVGGMHVDQQPKALPQDLED 285
            ||....:|  ||  ||..:.:| :|.|:...|....|||.:||:|.:||::..::.| |.|:.|.
Mouse   228 KYEIIASDLLKRDVSLPSLHQN-SLWLLRYDFVFEYPRPVMPNMIFLGGINCKKKGK-LTQEFEA 290

  Fly   286 FIQGAGEHGVIYFSLGTNVRSRNLSKDRRKILIDTFASLPQRILWKFDADELSDVPSNVLISPWF 350
            ::..:||||::.||||:.|  ..:.:.:...:.:....:||.:||::.....|::..|.::..|.
Mouse   291 YVNASGEHGIVVFSLGSMV--SEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWL 353

  Fly   351 PQQDILAHPNVKLFITHGGLQSTVECIHRGVPMLGLPFFYDQFRNMEHIKAQGIGLVLNYRDMTS 415
            ||.|:|.||..:.||||.|.....|.|..||||:.:|.|.||..|.:.::.:|.|:.||..:||:
Mouse   354 PQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTA 418

  Fly   416 DEFKDTIHQLLTEKSFGVKAKRTADRYRDQPMNPLDTAIWWTHYVLRHKGAPHMRVAGRNLDFIT 480
            |:.::.:..::..||:.....|.:..::|:|:.|||.|::|..||:|||||||:|.|..:|.:..
Mouse   419 DDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQ 483

  Fly   481 YHSLDVLGTFLLAVWAILSIVVL----CAIKLLRAILKSKKGNISPKQK 525
            ||||||:| ||||:  :|::|.:    ||....:..  ..||.:....|
Mouse   484 YHSLDVIG-FLLAI--VLTVVFIVFKCCAYGCRKCF--GGKGRVKKSHK 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35E2	NP_652623.2	MGT	31..443	CDD:273616	112/456 (25%)
		Glycosyltransferase_GTB-type	<247..517	CDD:471961	96/273 (35%)
Ugt1a6a	NP_659545.2	UDPGT	27..522	CDD:278624	153/553 (28%)