Protein Alignment Ugt35E2 and Ugt2a1

DIOPT Version :9

• Sequence 1: NP_652623.2
• Gene: Ugt35E2 / 53506
• FlyBaseID: FBgn0040255
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_444414.2
• Gene: Ugt2a1 / 94215
• MGIID: 2149905
• Length: 528
• Species: Mus musculus
• Alignment Length: 546
• Identity: 155/546 - (28%)
• Similarity: 272/546 - (49%)
• Gaps: 67/546 - (12%)

  Fly    10 LIVLVVALLPVLLEGARILGVFPIPSHSHYYHALPYLKKLASLGHEIT--------SVSPFPLKE 66
            |..|.::||.:.| |..:| ::|:.. ||:.:....:.:|....|.:|        .::|..: .
Mouse     7 LCSLQISLLGMSL-GGNVL-IWPMEG-SHWLNVKIIIDELLRKEHNVTVLVASGALFITPSSI-S 67

  Fly    67 PVANIHDIPVPELFDNIEEIVGN-----LTNRKG---TW----------NEFEYINQYTLGLVEK 113
            |.......|||...:.||.::.:     |.||..   .|          .||..:::   |:.:.
Mouse    68 PSLTFEIYPVPFGKEKIESVIKDFVLTWLENRPSPSTIWTFYKEMAKVIEEFHLVSR---GICDG 129

  Fly   114 VLENDGVRREILQPESLQFDLIIVDLWRLDALYG----LAAYFDAPIIGIASYGTDWKIDELVGN 174
            ||:|:.:..: ||.|  :|::::     .|.::.    :|.....|.|....:.....:::..|.
Mouse   130 VLKNEKLMSK-LQKE--KFEVLL-----SDPVFPCGDIVALKLGIPFIYSLRFSPASTVEKHCGK 186

  Fly   175 VS-PLAYLQSPSFNWFDLDTYGGRLGHFVDQSM-------AWINWHWRHEERHEAVYRKYFPKIA 231
            |. |.:|:.:......|..::..|:.:|:...|       .|..|        ::.|.|   .:.
Mouse   187 VPFPPSYVPAILSELTDQMSFTDRVRNFISYRMQDYMFETLWKQW--------DSYYTK---ALG 240

  Fly   232 DKRSLSEITRNFALILVNQHFTMAPPRPYVPNIIEVGGMHVDQQPKALPQDLEDFIQGAGEHGVI 296
            ...:|.|......:.|:..::....||||:||...|||:|. :..|.||:::|:|:|.:||||::
Mouse   241 RPTTLCETMGKAEIWLMRTYWDFEFPRPYLPNFEFVGGLHC-KPAKPLPKEMEEFVQTSGEHGIV 304

  Fly   297 YFSLGTNVRSRNLSKDRRKILIDTFASLPQRILWKFDADELSDVPSNVLISPWFPQQDILAHPNV 361
            .||||:.|  :||:.::..::....|.:||::||::.......:.||..:..|.||.|:|.||..
Mouse   305 VFSLGSMV--KNLTDEKANLIASALAQIPQKVLWRYKGKIPDTLGSNTRLFDWIPQNDLLGHPKT 367

  Fly   362 KLFITHGGLQSTVECIHRGVPMLGLPFFYDQFRNMEHIKAQGIGLVLNYRDMTSDEFKDTIHQLL 426
            :.||||||.....|.|:.|:||:|:|.|.||..|:.|:||:|..:.:|...|||.:..:.:..::
Mouse   368 RAFITHGGTNGIYEAIYHGIPMVGVPMFADQPDNIAHMKAKGAAVEVNMNTMTSSDLLNALRTVI 432

  Fly   427 TEKSFGVKAKRTADRYRDQPMNPLDTAIWWTHYVLRHKGAPHMRVAGRNLDFITYHSLDVLGTFL 491
            .|.|:...|.|.:..:.|||:.|||.|::|..:|:|||||.|:|||..:|.:..||||||:|..|
Mouse   433 NEPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLL 497

  Fly   492 LAVWAILSIVVLCAIKLLRAILKSKK 517
            ..|.:.:.:|..|.:.:.:.:.|:.|
Mouse   498 ACVASAILLVAKCCLFIFQKVGKTGK 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35E2	NP_652623.2	egt	23..481	CDD:223071	137/495 (28%)
		YjiC	26..440	CDD:224732	117/451 (26%)
Ugt2a1	NP_444414.2	UDPGT	21..516	CDD:278624	147/522 (28%)
		egt	<267..487	CDD:223071	88/222 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840244
Domainoid	1	1.000	259	1.000	Domainoid score	I1975
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2975
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm42461
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.690