Protein Alignment Ugt35E2 and Ugt2a1

DIOPT Version :10

• Sequence 1: NP_652623.2
• Gene: Ugt35E2 / 53506
• FlyBaseID: FBgn0040255
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: XP_063129643.1
• Gene: Ugt2a1 / 63867
• RGDID: 69432
• Length: 737
• Species: Rattus norvegicus
• Alignment Length: 516
• Identity: 149/516 - (28%)
• Similarity: 262/516 - (50%)
• Gaps: 55/516 - (10%)

  Fly    37 SHYYHALPYLKKLASLGHEIT----SVSPFPLKEPVA--NIHDIPVPELFDNIEEIVGNL----T 91
            ||:.:....|::|....|.:|    |.:.|....|.|  :..:|||......|:|::.::    .
  Rat   241 SHWLNIKILLEELVQRNHSVTVLAASETLFINSSPDAFISFEEIPVSYTRSKIDEMIEHMIALWL 305

  Fly    92 NRKGT----WNEFEYINQYTLGL--VEKVLENDGVRREILQPESLQ---FDLIIVD----LWRLD 143
            :.:.|    |..::.:.:.....  :.|.: .|||.:.......||   ||::|.|    ...|.
  Rat   306 DHRPTPLTMWAFYKELGKLFAAFYKINKQI-CDGVLKNATLMARLQKGGFDVLISDPVTMCGELV 369

  Fly   144 AL-YGLAAYFDAPIIGIASYGTDWKIDELVGNV-SPLAYLQSPSFNWFDLDTYGGRLGHFVDQSM 206
            || .|:      |.:....:...:.::...|.: :|::|:.:......|..|:|.|:.:.:..|:
  Rat   370 ALKLGI------PFVYTLRFSPAFTVERHCGKIPTPVSYVPAALSELTDQMTFGERVKNTISYSL 428

  Fly   207 A-------WINWHWRHEERHEAVYRKYFPKIADK-RSLSEITRNFALILVNQHFTMAPPRPYVPN 263
            .       |..|:            .|:.::..: .:|.|......:.|:..::....||||:||
  Rat   429 QDYIFKSYWGEWN------------SYYSRVLGRPTTLCETMGKAEIWLMRTYWDFEFPRPYLPN 481

  Fly   264 IIEVGGMHVDQQPKALPQDLEDFIQGAGEHGVIYFSLGTNVRSRNLSKDRRKILIDTFASLPQRI 328
            ...|||:|. :..|.||:::|:|:|.:|||||:.||||:.|  :||::::..::....|.:||::
  Rat   482 FEFVGGLHC-KPAKPLPKEMEEFVQTSGEHGVVVFSLGSMV--KNLTEEKANLIASALAQIPQKV 543

  Fly   329 LWKFDADELSDVPSNVLISPWFPQQDILAHPNVKLFITHGGLQSTVECIHRGVPMLGLPFFYDQF 393
            ||::.....:.:.||..:..|.||.|:|.||..:.||||||.....|.|:.|:||:|:|.|.||.
  Rat   544 LWRYKGKIPATLGSNTRLFDWIPQNDLLGHPKTRAFITHGGTNGIYEAIYHGIPMVGVPMFADQP 608

  Fly   394 RNMEHIKAQGIGLVLNYRDMTSDEFKDTIHQLLTEKSFGVKAKRTADRYRDQPMNPLDTAIWWTH 458
            .|:.|:||:|..:.:|...|||.:....:..::.|..:...|.|.:..:.|||:.|||.|::|..
  Rat   609 DNIAHMKAKGAAVEVNMNTMTSADLLSAVRAVINEPFYKENAMRLSRIHHDQPVKPLDRAVFWIE 673

  Fly   459 YVLRHKGAPHMRVAGRNLDFITYHSLDVLGTFLLAVWAILSIVVLCAIKLLRAILKSKKGN 519
            :|:|||||.|:|||..:|.:..||||||:|..|..:.:.:.:|:.|.:.:.:.|.|:.|.|
  Rat   674 FVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLACMASAILLVIKCCLFVFQKIGKTGKKN 734

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35E2	NP_652623.2	MGT	31..443	CDD:273616	116/438 (26%)
		Glycosyltransferase_GTB-type	<247..517	CDD:471961	102/269 (38%)
Ugt2a1	XP_063129643.1	None