Protein Alignment Ugt35E2 and Ugt1a5

DIOPT Version :10

• Sequence 1: NP_652623.2
• Gene: Ugt35E2 / 53506
• FlyBaseID: FBgn0040255
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_001034638.1
• Gene: Ugt1a5 / 574523
• RGDID: 1583689
• Length: 531
• Species: Rattus norvegicus
• Alignment Length: 540
• Identity: 152/540 - (28%)
• Similarity: 269/540 - (49%)
• Gaps: 50/540 - (9%)

  Fly    11 IVLVVALLPVLLEGARILGVFPIPSHSHYYHALPYLKKLASLGHEITSVSP----FPLKEPVANI 71
            ::|::..|| ..||.::| |||:.. ||:......:::|.:.||:...::|    ...:|....:
  Rat    13 LLLLLYALP-WAEGGKVL-VFPMEG-SHWLSMRDVVRELHARGHQAVVLAPEVTVHIKEEDFFTL 74

  Fly    72 HDIPVP--------ELFDNIEEIVGNLTNRKGTWNE----FEYINQYTLGLVEKVLENDGVRREI 124
            ...|||        ::..|| ::|....|...|:.|    .:.|:...|.....:|.|..:.:.:
  Rat    75 QTYPVPYTRQGFRQQMMRNI-KVVFETGNYVKTFLETSEILKNISTVLLRSCMNLLHNGSLLQHL 138

  Fly   125 LQPESLQFDLIIVD-LWRLDALYGLAAYFDAPIIGIASY---GTDWKIDELVGNVSPLAYLQSPS 185
               .|..||:::.| :....|:  ||.|...|.:....|   |.|   .|......|.:|:.:..
  Rat   139 ---NSSSFDMVLTDPVIPCGAV--LAKYLGIPTVFFLRYIPCGID---SEATQCPKPSSYIPNLL 195

  Fly   186 FNWFDLDTYGGRLGHFVDQSMAWINWHWRHEERHEAVYRKYFPKIADKRSLSEITRNFALILVNQ 250
            ....|..|:..|:.:.:.........|:.. .|:|::..:...:   :.||.|:..:.::.|...
  Rat   196 TMLSDHMTFLQRVKNMLYPLALKYICHFSF-TRYESLASELLQR---EVSLVEVLSHASVWLFRG 256

  Fly   251 HFTMAPPRPYVPNIIEVGGMH-VDQQPKALPQDLEDFIQGAGEHGVIYFSLGTNVRSRNLSKDRR 314
            .|....|||.:||::.:||:: |.::|  |.|:.|.::..:||||::.||||:.|  ..:.:.:.
  Rat   257 DFVFDYPRPVMPNMVFIGGINCVIKKP--LSQEFEAYVNASGEHGIVVFSLGSMV--SEIPEKKA 317

  Fly   315 KILIDTFASLPQRILWKFDADELSDVPSNVLISPWFPQQDILAHPNVKLFITHGGLQSTVECIHR 379
            ..:.:....:||.:||::.....|::..|.::..|.||.|:|.||..:.||||.|.....|.|..
  Rat   318 MEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARAFITHSGSHGIYEGICN 382

  Fly   380 GVPMLGLPFFYDQFRNMEHIKAQGIGLVLNYRDMTSDEFKDTIHQLLTEKSFGVKAKRTADRYRD 444
            ||||:.:|.|.||..|.:.::.:|.|:.||..:||:|:.::.:..::..||:.....|.:..::|
  Rat   383 GVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKD 447

  Fly   445 QPMNPLDTAIWWTHYVLRHKGAPHMRVAGRNLDFITYHSLDVLGTFLLAVWAILSIVVL----CA 505
            :|:.|||.|::|..||:|||||||:|.|..:|.:..||||||:| ||||:  :|::|.:    ||
  Rat   448 RPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIG-FLLAI--VLTVVFIVYKSCA 509

  Fly   506 IKLLRAILKSKKGNISPKQK 525
            ....:..  ..||.:....|
  Rat   510 YGCRKCF--GGKGRVKKSHK 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35E2	NP_652623.2	MGT	31..443	CDD:273616	108/432 (25%)
		Glycosyltransferase_GTB-type	<247..517	CDD:471961	96/274 (35%)
Ugt1a5	NP_001034638.1	UDPGT	26..522	CDD:278624	146/519 (28%)