Protein Alignment Ugt35E2 and Ugt2a2

DIOPT Version :9

• Sequence 1: NP_652623.2
• Gene: Ugt35E2 / 53506
• FlyBaseID: FBgn0040255
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_001019319.1
• Gene: Ugt2a2 / 552899
• MGIID: 3576095
• Length: 528
• Species: Mus musculus
• Alignment Length: 549
• Identity: 157/549 - (28%)
• Similarity: 276/549 - (50%)
• Gaps: 68/549 - (12%)

  Fly     7 VLRLIVLVVALLPVLLEGARILGVFPIPSHSHYYHALPYLKKLASLGHEITSVSPFPL------K 65
            ||:|::..:.|..::|.|..:  |:|... ||:.:....|::|....|.:|.::|...      .
Mouse     5 VLQLLIFHLTLAEIVLSGNVV--VWPTDG-SHWLNIKILLEELVQRNHSVTVLAPSETLFINSRL 66

  Fly    66 EPVANIHDIPVPELFDNIEEIVGNL----TNRKGT----WNEFEYINQ-----YTLG--LVEKVL 115
            :...|..:|||......|:||:.::    .:.:.|    |..::.:..     ||..  :.:.||
Mouse    67 DAFINFEEIPVSYTKSKIDEIIEHMIALWLDHRPTPLTMWTFYKELGNLLATFYTTNKQMCDGVL 131

  Fly   116 ENDGVRREILQPESLQ---FDLIIVD----LWRLDAL-YGLAAYFDAPIIGIASYGTDWKIDELV 172
            .|..|.      |.||   ||:::.|    ...|.|| .|:      |.:....:...:.::...
Mouse   132 NNPTVM------ERLQKGGFDVLLADPVTMCGELVALKLGI------PFVYTLRFSPAFTVERHC 184

  Fly   173 GNV-SPLAYLQSPSFNWFDLDTYGGRLGHFVDQSMA-------WINWHWRHEERHEAVYRKYFPK 229
            |.: :|::|:.:......|..::|.|:.:.:..|:.       |..|:            .|:.|
Mouse   185 GKIPAPISYVPAALSELTDQMSFGERVKNIISYSLQDYIFKTYWGEWN------------SYYSK 237

  Fly   230 IADK-RSLSEITRNFALILVNQHFTMAPPRPYVPNIIEVGGMHVDQQPKALPQDLEDFIQGAGEH 293
            :..: .:|.|......:.|:..::....||||:||...|||:|. :..|.||:::|:|:|.:|||
Mouse   238 VLGRPTTLCETMGKAEIWLMRTYWDFEFPRPYLPNFEFVGGLHC-KPAKPLPKEMEEFVQTSGEH 301

  Fly   294 GVIYFSLGTNVRSRNLSKDRRKILIDTFASLPQRILWKFDADELSDVPSNVLISPWFPQQDILAH 358
            |::.||||:.|  :||:.::..::....|.:||::||::.......:.||..:..|.||.|:|.|
Mouse   302 GIVVFSLGSMV--KNLTDEKANLIASALAQIPQKVLWRYKGKIPDTLGSNTRLFDWIPQNDLLGH 364

  Fly   359 PNVKLFITHGGLQSTVECIHRGVPMLGLPFFYDQFRNMEHIKAQGIGLVLNYRDMTSDEFKDTIH 423
            |..:.||||||.....|.|:.|:||:|:|.|.||..|:.|:||:|..:.:|...|||.:..:.:.
Mouse   365 PKTRAFITHGGTNGIYEAIYHGIPMVGVPMFADQPDNIAHMKAKGAAVEVNMNTMTSSDLLNALR 429

  Fly   424 QLLTEKSFGVKAKRTADRYRDQPMNPLDTAIWWTHYVLRHKGAPHMRVAGRNLDFITYHSLDVLG 488
            .::.|.|:...|.|.:..:.|||:.|||.|::|..:|:|||||.|:|||..:|.:..||||||:|
Mouse   430 TVINEPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIG 494

  Fly   489 TFLLAVWAILSIVVLCAIKLLRAILKSKK 517
            ..|..|.:.:.:|..|.:.:.:.:.|:.|
Mouse   495 FLLACVASAILLVAKCCLFIFQKVGKTGK 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35E2	NP_652623.2	egt	23..481	CDD:223071	139/495 (28%)
		YjiC	26..440	CDD:224732	119/451 (26%)
Ugt2a2	NP_001019319.1	UDPGT	22..516	CDD:278624	150/523 (29%)
		egt	<267..487	CDD:223071	88/222 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840196
Domainoid	1	1.000	259	1.000	Domainoid score	I1975
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2975
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm42461
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.790