Protein Alignment Ugt35E2 and Ugt1a2

DIOPT Version :10

• Sequence 1: NP_652623.2
• Gene: Ugt35E2 / 53506
• FlyBaseID: FBgn0040255
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_958826.1
• Gene: Ugt1a2 / 396527
• RGDID: 1549741
• Length: 533
• Species: Rattus norvegicus
• Alignment Length: 549
• Identity: 154/549 - (28%)
• Similarity: 276/549 - (50%)
• Gaps: 68/549 - (12%)

  Fly    11 IVLVVALLPVLLEGARILGVFPIPSHSHYYHALPYLKKLASLGHEITSVSP---FPLK-EPVANI 71
            ::|::..|| ..||.::| |||:.. ||:......:::|.:.||:...::|   ..:| |....:
  Rat    15 LLLLLCALP-WAEGGKVL-VFPMEG-SHWLSMRDVVRELHARGHQAVVLAPEVTVHMKGEDFFTL 76

  Fly    72 HDIPVPELFDNIE-EIVGNLTNRKGTWNEFE---YINQY--TLGLVEK-----------VLENDG 119
            .....|...:..: ||:||.  :||    ||   ::..:  |:..::|           :|.|
  Rat    77 QTYAFPYTKEEYQREILGNA--KKG----FEPQHFVKTFFETMASIKKFFDLYANSCAALLHN-- 133

  Fly   120 VRREILQPESLQFDLIIVD-LWRLDALYGLAAYFDAPIIGI---ASYGTDWKIDELVGNVSPLAY 180
             :..|.|..|..||:::.| ::...||  ||.|...|.:..   ...|.|::..:.   ..|.:|
  Rat   134 -KTLIQQLNSSSFDVVLTDPVFPCGAL--LAKYLQIPAVFFLRSVPCGIDYEATQC---PKPSSY 192

  Fly   181 LQSPSFNWFDLDTYGGRLGHFV-DQSMAWINWHWRHEERHEAV--YRKYFPKIADKR-SLSEITR 241
            :.:......|..|:..|:.:.: ..::.:|        .|.::  |.....::..:. ||.|:..
  Rat   193 IPNLLTMLSDHMTFLQRVKNMLYPLTLKYI--------CHLSITPYESLASELLQREMSLVEVLS 249

  Fly   242 NFALILVNQHFTMAPPRPYVPNIIEVGGMH-VDQQPKALPQDLEDFIQGAGEHGVIYFSLGTNVR 305
            :.::.|....|....|||.:||::.:||:: |.::|  |.|:.|.::..:||||::.||||:.|
  Rat   250 HASVWLFRGDFVFDYPRPIMPNMVFIGGINCVIKKP--LSQEFEAYVNASGEHGIVVFSLGSMV- 311

  Fly   306 SRNLSKDRRKILIDTFASLPQRILWKFDADELSDVPSNVLISPWFPQQDILAHPNVKLFITHGGL 370
             ..:.:.:...:.:....:||.:||::.....|::..|.::..|.||.|:|.||..:.||||.|.
  Rat   312 -SEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARAFITHSGS 375

  Fly   371 QSTVECIHRGVPMLGLPFFYDQFRNMEHIKAQGIGLVLNYRDMTSDEFKDTIHQLLTEKSFGVKA 435
            ....|.|..||||:.:|.|.||..|.:.::.:|.|:.||..:||:|:.::.:..::..||:....
  Rat   376 HGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENI 440

  Fly   436 KRTADRYRDQPMNPLDTAIWWTHYVLRHKGAPHMRVAGRNLDFITYHSLDVLGTFLLAVWAILSI 500
            .|.:..::|:|:.|||.|::|..||:|||||||:|.|..:|.:..||||||:| ||||:  :|::
  Rat   441 MRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIG-FLLAI--VLTV 502

  Fly   501 VVL----CAIKLLRAILKSKKGNISPKQK 525
            |.:    ||....:..  ..||.:....|
  Rat   503 VFIVYKSCAYGCRKCF--GGKGRVKKSHK 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35E2	NP_652623.2	MGT	31..443	CDD:273616	110/441 (25%)
		Glycosyltransferase_GTB-type	<247..517	CDD:471961	96/274 (35%)
Ugt1a2	NP_958826.1	UDPGT	28..524	CDD:278624	148/528 (28%)