Protein Alignment Ugt35E2 and Ugt1a5

DIOPT Version :10

• Sequence 1: NP_652623.2
• Gene: Ugt35E2 / 53506
• FlyBaseID: FBgn0040255
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_964005.2
• Gene: Ugt1a5 / 394433
• MGIID: 3032634
• Length: 529
• Species: Mus musculus
• Alignment Length: 565
• Identity: 160/565 - (28%)
• Similarity: 277/565 - (49%)
• Gaps: 84/565 - (14%)

  Fly     1 MPMSMLVLRLIVLVVALLPVLLEGARILGVFPIPSHSHYYHALPYLKKLASLGHEITSVSP---F 62
            ||:..||   .:|::..|| ..||.::| |||: ..||:......:::|.:.||:...::|   .
Mouse     5 MPLQGLV---GLLLLCALP-WTEGEKVL-VFPV-GGSHWLSMRDVVRELHAQGHQTVVLAPEVNM 63

  Fly    63 PLKEP---VANIHDIPVPELFDNIEEIVGNLTNRKGTWNEFEYI--------NQYT--LGLVEKV 114
            .:||.   ...::.:|...  ..:||::.||.....|.|..:.|        |..|  |.....:
Mouse    64 RIKEEDFFTFKVYAVPYTR--QELEEMMENLKVFFDTGNYMKKIFKTSEALRNMSTVLLKTCTNI 126

  Fly   115 LENDGVRREILQPESLQFDLIIVD-LWRLDALYGLAAYFDAPIIGIASY---GTDWKIDELVGNV 175
            |.|:.:...:   .|..||::..| ::...||  ||.|...|.:....|   |.:::..:.   .
Mouse   127 LHNESLLHHL---NSSSFDVVFTDPVFPCGAL--LAKYLGIPAVFFLRYIPCGIEYEATQC---P 183

  Fly   176 SPLAYLQSPSFNWFDLDTYGGRLGHFVD--QSMAWINWHWRHEERHEAVYRKY--------FPKI 230
            ||.:|:.    |.|.      ||...:|  |.:..:.:|         :..||        :..:
Mouse   184 SPSSYIP----NLFT------RLSDHMDFLQRVQNMLYH---------LVLKYICHLLITPYESL 229

  Fly   231 ADKRSLSEITR----NFALI-LVNQHFTMAPPRPYVPNIIEVGGMH-VDQQPKALPQDLEDFIQG 289
            |.:....|::.    ::|.: |....|.:..|||.:||::.:||:: |.::|  |.|:.|.::..
Mouse   230 ASELFQREVSSVELFSYASVWLFRGDFVLDYPRPIMPNMVFIGGINCVTKKP--LSQEFEAYVNA 292

  Fly   290 AGEHGVIYFSLGTNVRSRNLSKDRRKILIDTFASLPQRILWKFDADELSDVPSNVLISPWFPQQD 354
            :||||::.||||:.|  ..:.:.:...:.:....:||.:||::.....|::..|.::..|.||.|
Mouse   293 SGEHGIVVFSLGSMV--SEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQND 355

  Fly   355 ILAHPNVKLFITHGGLQSTVECIHRGVPMLGLPFFYDQFRNMEHIKAQGIGLVLNYRDMTSDEFK 419
            :|.||..:.||||.|.....|.|..||||:.:|.|.||..|.:.::.:|.|:.||..:||:|:.:
Mouse   356 LLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLE 420

  Fly   420 DTIHQLLTEKSFGVKAKRTADRYRDQPMNPLDTAIWWTHYVLRHKGAPHMRVAGRNLDFITYHSL 484
            :.:..::..||:.....|.:..::|:|:.|||.|::|..||:|||||||:|.|..:|.:..||||
Mouse   421 NALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSL 485

  Fly   485 DVLGTFLLAVWAILSIVVL----CAIKLLRAILKSKKGNISPKQK 525
            ||:| ||||:  :|::|.:    ||....:..  ..||.:....|
Mouse   486 DVIG-FLLAI--VLTVVFIVFKCCAYGCRKCF--GGKGRVKKSHK 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35E2	NP_652623.2	MGT	31..443	CDD:273616	112/447 (25%)
		Glycosyltransferase_GTB-type	<247..517	CDD:471961	96/274 (35%)
Ugt1a5	NP_964005.2	UDPGT	26..520	CDD:278624	150/533 (28%)