Protein Alignment Ugt35E2 and Ugt1a1

DIOPT Version :10

• Sequence 1: NP_652623.2
• Gene: Ugt35E2 / 53506
• FlyBaseID: FBgn0040255
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_036815.1
• Gene: Ugt1a1 / 24861
• RGDID: 3935
• Length: 535
• Species: Rattus norvegicus
• Alignment Length: 557
• Identity: 157/557 - (28%)
• Similarity: 267/557 - (47%)
• Gaps: 70/557 - (12%)

  Fly     4 SMLVLRLIVLVVALLPVLLEGARILGVFPIPSHSHYYHALPYLKKLASLGHEITSVSPFPLKEPV 68
            |:|:|..::|.| |.|......::| |.||.. ||:...|..:::|...|||:..::      |.
  Rat    10 SLLLLPCLLLCV-LGPSASHAGKLL-VIPIDG-SHWLSMLGVIQQLQQKGHEVVVIA------PE 65

  Fly    69 ANIH----------DIPVPELFDNIEEI---VGN--------LTNRKGTWNEFEYINQYTLGLVE 112
            |:||          ..|||...:|:...   :|.        |.....|:|:.:..:...|....
  Rat    66 ASIHIKEGSFYTMRKYPVPFQNENVTAAFVELGRSVFDQDPFLLRVVKTYNKVKRDSSMLLSGCS 130

  Fly   113 KVLENDGVRREILQPESLQFDLIIVDLWRLDALYGLAAYFDAPIIGIASYGTDWKID-ELVGNVS 176
            .:|.|......:   |...||.::.|.: |.....:|.|...|.:...: .....:| |.....:
  Rat   131 HLLHNAEFMASL---EQSHFDALLTDPF-LPCGSIVAQYLSLPAVYFLN-ALPCSLDLEATQCPA 190

  Fly   177 PLAYLQSPSFNWFDLDTYGGRLGHFVDQSMAWI-----NWHWRHEERHEAVYRKY---FPKIADK 233
            ||:|:..      .|.:...|: :|:.:....|     |:..|      .||..|   ..:|..|
  Rat   191 PLSYVPK------SLSSNTDRM-NFLQRVKNMIIALTENFLCR------VVYSPYGSLATEILQK 242

  Fly   234 R-SLSEITRNFALILVNQHFTMAPPRPYVPNIIEVGGMHVDQQPKALPQDLEDFIQGAGEHGVIY 297
            . ::.::....::.|:...|....|||.:||::.:||::. .|.|||.|:.|.::..:||||::.
  Rat   243 EVTVKDLLSPASIWLMRNDFVKDYPRPIMPNMVFIGGINC-LQKKALSQEFEAYVNASGEHGIVV 306

  Fly   298 FSLGTNVRSRNLSKDRRKILIDTFASLPQRILWKFDADELSDVPSNVLISPWFPQQDILAHPNVK 362
            ||||:.|  ..:.:.:...:.:....:||.:||::.....|::..|.::..|.||.|:|.||..:
  Rat   307 FSLGSMV--SEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKAR 369

  Fly   363 LFITHGGLQSTVECIHRGVPMLGLPFFYDQFRNMEHIKAQGIGLVLNYRDMTSDEFKDTIHQLLT 427
            .||||.|.....|.|..||||:.:|.|.||..|.:.::.:|.|:.||..:||:|:.::.:..::.
  Rat   370 AFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVIN 434

  Fly   428 EKSFGVKAKRTADRYRDQPMNPLDTAIWWTHYVLRHKGAPHMRVAGRNLDFITYHSLDVLGTFLL 492
            .||:.....|.:..::|:|:.|||.|::|..||:|||||||:|.|..:|.:..||||||:| |||
  Rat   435 NKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIG-FLL 498

  Fly   493 AVWAILSIVVL----CAIKLLRAILKSKKGNISPKQK 525
            |:  :|::|.:    ||....:..  ..||.:....|
  Rat   499 AI--VLTVVFIVYKSCAYGCRKCF--GGKGRVKKSHK 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35E2	NP_652623.2	MGT	31..443	CDD:273616	111/442 (25%)
		Glycosyltransferase_GTB-type	<247..517	CDD:471961	97/273 (36%)
Ugt1a1	NP_036815.1	UDPGT	30..526	CDD:278624	149/529 (28%)