Protein Alignment Ugt35E2 and Ugt2b5

DIOPT Version :9

• Sequence 1: NP_652623.2
• Gene: Ugt35E2 / 53506
• FlyBaseID: FBgn0040255
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_033493.3
• Gene: Ugt2b5 / 22238
• MGIID: 98900
• Length: 530
• Species: Mus musculus
• Alignment Length: 519
• Identity: 144/519 - (27%)
• Similarity: 256/519 - (49%)
• Gaps: 54/519 - (10%)

  Fly    30 VFPIPSHSHYYHALPYLKKLASLGHEITSVSPF------PLKEPVANIHDIPVPELFDNIEEIVG 88
            |:|: ..||:.:....|.:|...|||:|.:.|.      |.|.|.......|.....||:|....
Mouse    28 VWPM-EFSHWMNIKIILDELVQRGHEVTVLRPSAYYVLDPKKSPGLKFETFPTSVSKDNLENFFI 91

  Fly    89 NLTNRKGTW-----------------NEFEYINQYTLGLVEKVLENDGVRREILQPESLQFDLII 136
            ...:   .|                 |..:..:.|.|.|.:.|:.|..:..::   :..:||:::
Mouse    92 KFVD---VWTYEMPRDTCLSYSPLLQNMIDEFSDYFLSLCKDVVSNKELMTKL---QESKFDVLL 150

  Fly   137 VDLWRLDALYG--LAAYFDAPIIGIASYGTDWKIDELVGNVSPLAYLQSPSFNWFDLDTYGGRLG 199
            .|   ..|..|  :|.....|.:....:...::|::..|.     :|..||:....|...||::
Mouse   151 SD---PVASCGELIAELLQIPFLYSIRFSPGYQIEKSSGR-----FLLPPSYVPVILSGLGGQM- 206

  Fly   200 HFVDQ-----SMAWINWHWR--HEERHEAVYRKYFPKIADKRSLSEITRNFALILVNQHFTMAPP 257
            .|:::     .|.:.::.::  ::::.::.|.:|   :....:|.|......:.|:..::.:..|
Mouse   207 TFIERIKNMICMLYFDFWFQMFNDKKWDSFYSEY---LGRPTTLVETMGQAEMWLIRSNWDLEFP 268

  Fly   258 RPYVPNIIEVGGMHVDQQPKALPQDLEDFIQGAGEHGVIYFSLGTNVRSRNLSKDRRKILIDTFA 322
            .|.:||:..|||:|. :..|.||:|:|:|:|.:|:|||:.||||:.|  .|:::::...:....|
Mouse   269 HPTLPNVDYVGGLHC-KPAKPLPKDMEEFVQSSGDHGVVVFSLGSMV--SNMTEEKANAIAWALA 330

  Fly   323 SLPQRILWKFDADELSDVPSNVLISPWFPQQDILAHPNVKLFITHGGLQSTVECIHRGVPMLGLP 387
            .:||::|||||....:.:..|..:..|.||.|:|.||..|.|:||||.....|.|:.|:||:|:|
Mouse   331 QIPQKVLWKFDGKTPATLGHNTRVYKWLPQNDLLGHPKTKAFVTHGGANGVYEAIYHGIPMIGIP 395

  Fly   388 FFYDQFRNMEHIKAQGIGLVLNYRDMTSDEFKDTIHQLLTEKSFGVKAKRTADRYRDQPMNPLDT 452
            .|.:|..|:.|:.|:|..:.||.|.|:..:..:.:.:::....:...|...:..:.||||.|||.
Mouse   396 LFGEQHDNIAHMVAKGAAVALNIRTMSKSDVLNALEEVIENPFYKKNAMWLSTIHHDQPMKPLDR 460

  Fly   453 AIWWTHYVLRHKGAPHMRVAGRNLDFITYHSLDVLGTFLLAVWAILSIVVLCAIKLLRAILKSK 516
            |::|..:|:|||.|.|:|..|.||.:..||||||:|..|..|...:.:.|.|.:.:.|..:|.:
Mouse   461 AVFWIEFVMRHKRAKHLRPLGHNLTWYQYHSLDVIGFLLSCVATTIVLSVKCLLFIYRFFVKKE 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35E2	NP_652623.2	egt	23..481	CDD:223071	131/482 (27%)
		YjiC	26..440	CDD:224732	112/441 (25%)
Ugt2b5	NP_033493.3	egt	8..489	CDD:223071	131/482 (27%)
		UDPGT	24..527	CDD:278624	144/519 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840403
Domainoid	1	1.000	259	1.000	Domainoid score	I1975
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2975
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm42461
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.690