DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt35E2 and ugt-55

DIOPT Version :9

Sequence 1:	NP_652623.2	Gene:	Ugt35E2 / 53506	FlyBaseID:	FBgn0040255	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	NP_506073.2	Gene:	ugt-55 / 188072	WormBaseID:	WBGene00011452	Length:	512	Species:	Caenorhabditis elegans

Alignment Length:	516	Identity:	119/516 - (23%)
Similarity:	200/516 - (38%)	Gaps:	109/516 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 MSMLVLRLIVLVVALLPVLLEGARILGVFP--IPSHSHYYHALPYLKKLASL----GHEITSVSP 61
            |.:|.|..::.:...........|||...|  ||||      :.::..:|:|    ||.:..|..
Worm     1 MQLLTLPTLIFIFLNYGTPCLSLRILVYSPRMIPSH------VAFVANIANLLGQRGHNVVVVDN 59

  Fly    62 FPLKEPVANIHDIPV------PELFDNIEEIVGNLTNRKGTW---NEFEYINQYTLGLVEKVLEN 117
            . |:..::|..|:.|      .|...|:.:::.:.:.....|   ||.|.        .:||::.
Worm    60 V-LRSDISNKLDLKVIEKVVKVETSANVAKLLADQSIPINFWSMRNEPEE--------QKKVMKQ 115

  Fly   118 DGV-----RREILQPESLQFDLIIVDLWRLDALYGLAAYFDAPIIGI------------ASYGTD 165
            .|:     .:.::..|...|:    :|..|:..:|:...||...|||            :|.|..
Worm   116 LGIIFLEQCKYLVSKEETVFN----ELKHLEFDFGIHEVFDICGIGIFEKLGIRKSVILSSTGMR 176

  Fly   166 WKIDELVGNVSPLAYLQSPSFNWFDLDTYGGRLGHFVDQSMAWINWHWRHEERHEAVYRKYF--- 227
            ..::|.:|..|   .||..|.    |..||..:..:          ..|...:..:.:|.:|
Worm   177 DIVNEALGISS---QLQDASI----LSDYGNSIPFY----------GIRRNLKFHSAWRNFFEVQ 224

  Fly   228 -----PKIADKRSLSEITRNFALILVNQHFTMAPPRPYVPNIIEVGGMHVDQQPKALPQDLE-DF 286
                 |......|...:.|...|:.:|.|......||:...:.|:||:..     ..|..|: ::
Worm   225 SKTLEPLFETTSSFENLLRFSNLMFLNTHELADAHRPWSRRVHEIGGISF-----KFPMPLKNEY 284

  Fly   287 IQGAGEH-GVIYFSLGTNVRSRNLSKDRRKILIDTFASLPQRI-LWKFDADE---LSDVPSNVLI 346
            |....:: .:|..|.||...|..:.:..:..||:||...|..: :||::.|:   ..:...||:.
Worm   285 INLFNKYNSIILVSFGTTTPSFLMPEKYKNTLINTFQRFPDFLFIWKYEKDDEFTQKNKKGNVVF 349

  Fly   347 SPWFPQQDILAHPNVKLFITHGGLQSTVECIHRGVPMLGLPFFYDQFRNMEHIKAQGIGLVLNYR 411
            ..:.||.|:|....:||||||||..|.:|..|.....|..|.|.||.||.:.....|:..||...
Worm   350 KKFLPQVDLLESRKIKLFITHGGQNSLLETFHSNTRTLITPLFGDQHRNAQIALENGLSHVLLKD 414

  Fly   412 DMTSDEF------------KDTIHQLLTEKSFGVKAKRTADR---------YRDQPMNPLD 451
            .:.::|.            |.....||...|....||:|::.         |.|. ::||:
Worm   415 QLANEELVYAAIKQGTESNKKLDDNLLKLSSNLKNAKQTSENLFLDTVESTYTDN-LSPLN 474

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35E2	NP_652623.2	egt	23..481	CDD:223071	116/496 (23%)
Ugt35E2	NP_652623.2	YjiC	26..440	CDD:224732	112/471 (24%)
ugt-55	NP_506073.2	UDPGT	35..>399	CDD:278624	94/404 (23%)
ugt-55	NP_506073.2	Glycosyltransferase_GTB_type	<247..>399	CDD:299143	47/156 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.810