DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt35E2 and ugt-64

DIOPT Version :9

Sequence 1:	NP_652623.2	Gene:	Ugt35E2 / 53506	FlyBaseID:	FBgn0040255	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	NP_503978.1	Gene:	ugt-64 / 178774	WormBaseID:	WBGene00015577	Length:	501	Species:	Caenorhabditis elegans

Alignment Length:	533	Identity:	119/533 - (22%)
Similarity:	223/533 - (41%)	Gaps:	84/533 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 IVLVVALLPVLLEGARILGVFPIPSHSHYYHALPYLKKLASLGHEITSVSPFPLKEPVANIHDIP 75
            |:.:..|.|...:.|::|........||.....|.:.:|....| .|::.....|..:    |..
Worm     6 ILYLFLLFPNFCDSAKVLLTVMDQGRSHATSITPLMHRLQKNDH-TTALEMATYKPDI----DFG 65

  Fly    76 VPELFDNIEEIVGNLTNRK----GTWNEFEYINQ---YTLGLV--EKVLENDGVRREILQPESLQ 131
            :.|.|.|:.....|..::.    ...:||.:::|   :..|.:  :::|::.  :...|:..:..
Worm    66 MEERFINMSGFENNFISKDFFKIAFEDEFTFVHQAVPFIFGSISCDRILKHQ--KNRYLEIANEN 128

  Fly   132 FDLIIVDLWRLDALYGLAAYFDAPIIG---IASYGTDWKIDELVGNVSPLAYLQSPSFNWFDLDT 193
            :||.:     .|:|:....|..|.|.|   :..:.:|  ::...|           ||..|..:
Worm   129 WDLFL-----SDSLFSPCGYAMAEITGKPHVMMHSSD--VESAHG-----------SFKGFSRN- 174

  Fly   194 YGGRLGHFVDQSMA--WINWHWRHEERHEAVYR-KYFPKIADKRSLSEITRNFALILV------- 248
            |...:.:|:..||:  .|..:|     |..|.. .:|.......:::...:.:||..:
Worm   175 YAIMVPNFLPYSMSNFTIEKYW-----HRVVSTVDWFGSAFITGAVAGFAQKWALRSIIPFPFFS 234

  Fly   249 ----NQHFTMA---PPRPYVPNIIEVG---------GMHVDQQPKALPQDLEDFIQGAGEHGVIY 297
                |:..:.:   .|.|..|    ||         |.:...|.|.|.:|.|.|:......|.|.
Worm   235 FYDYNRRSSFSFTDMPDPLYP----VGARTNDYFSFGTYCTAQKKVLDEDWEQFVSDPKSKGTIL 295

  Fly   298 FSLGTNVRSRNLSKDRRKILIDTFASLPQ-RILWKFDADELSDVPSNVLISPWFPQQDILAHPNV 361
            .:.||.:..|...:::.:|.::|...|.: |::|....|....:..:|.||.|.|||.||.|...
Worm   296 VAFGTIIDWRFAPEEKFEIFLNTLNRLTEYRVIWSMKGDRPKGLGEHVKISSWVPQQQILNHKKT 360

  Fly   362 KLFITHGGLQSTVECIHRGVPMLGLPFFYDQFRNMEHIKAQGIGLVLNYRDMTSDEFKDTIHQLL 426
            .||::||||:|..|.:....|.|.:|.|.:|.||....|::|...:||...::....::.|.:::
Worm   361 VLFLSHGGLKSVKEAVCSATPSLFMPMFAEQMRNAWLAKSKGFARILNKFHLSEQYLENHIREVV 425

  Fly   427 TEKSFGVKAKRTADRYRDQPMNPLDTAIWWTHYVLRHKGAPHMRVAGRNLD--FITYHSLDVLGT 489
            ..||:.::|::....:.||||..||.|.:....:.::.|........:.:|  ::|..:||
Worm   426 EHKSYQIQAEQFLSTFTDQPMPALDEAAFKFERLFKYNGKMPKFFYPKTIDLSYLTALNLD---- 486

  Fly   490 FLLAVWAILSIVV 502
                :|.|:.:|:
Worm   487 ----IWVIVPLVL 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35E2	NP_652623.2	egt	23..481	CDD:223071	110/498 (22%)
Ugt35E2	NP_652623.2	YjiC	26..440	CDD:224732	100/452 (22%)
ugt-64	NP_503978.1	Glycosyltransferase_GTB_type	<271..468	CDD:299143	58/196 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010