Protein Alignment Ugt35E2 and Ugt1a7c

DIOPT Version :10

• Sequence 1: NP_652623.2
• Gene: Ugt35E2 / 53506
• FlyBaseID: FBgn0040255
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_569091.2
• Gene: Ugt1a7c / 154516
• RGDID: 620950
• Length: 531
• Species: Rattus norvegicus
• Alignment Length: 578
• Identity: 156/578 - (26%)
• Similarity: 269/578 - (46%)
• Gaps: 109/578 - (18%)

  Fly     1 MPMSMLVLRLIVLVVA-------LLPVLLEGARILGVFPIPSHSHYYHALPYLKKLASLGHEITS 58
            :|.| |.|.|.:|:.:       ||.|.::|            ||::.....::||...|||:..
  Rat     6 IPAS-LPLGLCLLLASGFGHAGKLLVVPMDG------------SHWFTMQMVVEKLLPKGHEVVV 57

  Fly    59 VSP---FPLKEPV-ANIHDIPVPELFDNIEEIVGNLTNRKGTWNEFEYI--NQYTLGLVEKVLEN 117
            |.|   :.|.:|: ..:....|....:::        ||     ||::.  :|:      |..:.
  Rat    58 VVPEVSWQLGKPLNFTVKTYSVSHTQEDL--------NR-----EFKFFIDSQW------KTQQE 103

  Fly   118 DGVRREILQPESLQFDLI------------IVDLWR---LDALY-------GL--AAYFDAPII- 157
            .||...:..|....|:|:            :|:..:   .||::       ||  |.||..|.:
  Rat   104 GGVLPLLTSPAQGFFELLFSHCRSLFKDKKLVEYLKQSSFDAVFLDPFDVCGLTVAKYFSLPSVV 168

  Fly   158 ---GIASYGTDWKIDELVGNVSPLAYLQSPSFNWFDLDTYGGRLGHFVDQSMAWINWHWRHEERH 219
               ||..:    .::|.....||.:|:........|..|:..|:            |:.......
  Rat   169 FSRGIFCH----YLEEGSQCPSPPSYVPRGILKLTDTMTFKERV------------WNLLSYMGE 217

  Fly   220 EAVYRKYFPKIADKRS--------LSEITRNFALILVNQHFTMAPPRPYVPNIIEVGGMHVDQQP 276
            .|....:|....|..|        ::::....::.|:...||:..|||.:||:|.:||::..|:
  Rat   218 HAFCPSFFKTATDIASEVLQTPVTMTDLFSPVSVWLLRTDFTLELPRPVMPNVIHIGGINCHQR- 281

  Fly   277 KALPQDLEDFIQGAGEHGVIYFSLGTNVRSRNLSKDRRKILIDTFASLPQRILWKFDADELSDVP 341
            |.|.::.|.::..:||||::.||||:.|  ..:.:.:...:.:....:||.:||::.....|::.
  Rat   282 KPLSKEFEAYVNASGEHGIVVFSLGSMV--SEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLA 344

  Fly   342 SNVLISPWFPQQDILAHPNVKLFITHGGLQSTVECIHRGVPMLGLPFFYDQFRNMEHIKAQGIGL 406
            .|.::..|.||.|:|.||..:.||||.|.....|.|..||||:.:|.|.||..|.:.::.:|.|:
  Rat   345 KNTILVKWLPQNDLLGHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGV 409

  Fly   407 VLNYRDMTSDEFKDTIHQLLTEKSFGVKAKRTADRYRDQPMNPLDTAIWWTHYVLRHKGAPHMRV 471
            .||..:||:|:.::.:..::..||:.....|.:..::|:|:.|||.|::|..||:|||||||:|.
  Rat   410 TLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRP 474

  Fly   472 AGRNLDFITYHSLDVLGTFLLAVWAILSIVVL----CAIKLLRAILKSKKGNISPKQK 525
            |..:|.:..||||||:| ||||:  :|::|.:    ||....:..  ..||.:....|
  Rat   475 AAHDLTWYQYHSLDVIG-FLLAI--VLTVVFIVYKSCAYGCRKCF--GGKGRVKKSHK 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35E2	NP_652623.2	MGT	31..443	CDD:273616	109/453 (24%)
		Glycosyltransferase_GTB-type	<247..517	CDD:471961	97/273 (36%)
Ugt1a7c	NP_569091.2	UDPGT	26..522	CDD:278624	149/550 (27%)