Protein Alignment Ugt35E2 and Ugt2b37

DIOPT Version :9

• Sequence 1: NP_652623.2
• Gene: Ugt35E2 / 53506
• FlyBaseID: FBgn0040255
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_444445.2
• Gene: Ugt2b37 / 112417
• MGIID: 2148239
• Length: 530
• Species: Mus musculus
• Alignment Length: 521
• Identity: 149/521 - (28%)
• Similarity: 263/521 - (50%)
• Gaps: 56/521 - (10%)

  Fly    30 VFPIPSHSHYYHALPYLKKLASLGHEITSVSPF------PLKEPVANIHDIPVPELFDNIEEIVG 88
            |:|: ..||:.:....|.:|...|||:|.:.|.      |.|.|.......|.....|::|....
Mouse    28 VWPM-EFSHWMNIKIILDELVQRGHEVTVLRPSAYYVLDPKKSPGLKFETFPTSVTKDDLENFFI 91

  Fly    89 NLTNRKGTW-----------------NEFEYINQYTLGLVEKVLENDGVRREILQPESLQFDLII 136
            .|.|   .|                 |.|:.::.|.|.|.:.|:.|   |:.:.:.:..:||:::
Mouse    92 QLLN---VWTYELSRDTCLSYSPLMQNMFDELSGYYLSLCKDVVSN---RQLMTKLQESKFDVLL 150

  Fly   137 VDLWRLDALYG---LAAYFDAPIIGIASYGTDWKIDELVGNVSPLAYLQSPSFNWFDLDTYGGRL 198
            .|    ...:|   :|.....|.:....:...::|::..|.     :|..||:....|...||::
Mouse   151 SD----PVAFGGELIAELLHIPFLYSLRFTAGYRIEKSSGR-----FLLPPSYVPVILSGLGGQM 206

  Fly   199 GHFVDQ-----SMAWINWHWR--HEERHEAVYRKYFPKIADKRSLSEITRNFALILVNQHFTMAP 256
             .|:::     .|.:.::.::  ::::.::.|.:|   :....:|:|......:.|:..::.:..
Mouse   207 -TFIERVKNMICMLYFDFWFQMPNDKKWDSFYTEY---LGRPTTLAETMGQAEMWLIRSNWDLEF 267

  Fly   257 PRPYVPNIIEVGGMHVDQQPKALPQDLEDFIQGAGEHGVIYFSLGTNVRSRNLSKDRRKILIDTF 321
            |.|.:||:..|||:|. :..|.||:|:|:::|.:|:|||:.||||:.|  .|:::::...:....
Mouse   268 PHPTLPNVDYVGGLHC-KPAKPLPKDMEEYVQSSGDHGVVVFSLGSMV--SNITEEKVNAIAWAL 329

  Fly   322 ASLPQRILWKFDADELSDVPSNVLISPWFPQQDILAHPNVKLFITHGGLQSTVECIHRGVPMLGL 386
            |.:||::|||||....:.:..|..:..|.||.|:|.||..|.||||||..|..|.|:.|:||:|:
Mouse   330 AQIPQKVLWKFDGKTPATLGHNTRVYKWLPQNDLLGHPKTKAFITHGGANSVYEAIYHGIPMIGI 394

  Fly   387 PFFYDQFRNMEHIKAQGIGLVLNYRDMTSDEFKDTIHQLLTEKSFGVKAKRTADRYRDQPMNPLD 451
            |.|.:|..|:.|:.|:|..:.||.|.|:..:..:.:.:::....:...|...:..:.||||.|||
Mouse   395 PLFGEQHDNIAHMVAKGAAVTLNIRTMSRSDVLNALEEVIENPFYKKNAMWLSTIHHDQPMKPLD 459

  Fly   452 TAIWWTHYVLRHKGAPHMRVAGRNLDFITYHSLDVLGTFLLAVWAILSIVVLCAIKLLRAILKSK 516
            .|::|..:|:|||.|.|:|..|.||.:..||||||:|..|..|.|.:.:.|.|.:.:.|..:..|
Mouse   460 RAVFWVEFVMRHKNAKHLRPLGHNLTWYQYHSLDVIGFLLACVAATVVLTVKCLLFIYRFFVTKK 524

  Fly   517 K 517
            |
Mouse   525 K 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35E2	NP_652623.2	egt	23..481	CDD:223071	134/483 (28%)
		YjiC	26..440	CDD:224732	115/442 (26%)
Ugt2b37	NP_444445.2	UDPGT	24..527	CDD:278624	149/521 (29%)
		Glycosyltransferase_GTB_type	42..>174	CDD:299143	30/141 (21%)
		egt	<270..489	CDD:223071	84/221 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840405
Domainoid	1	1.000	259	1.000	Domainoid score	I1975
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2975
Isobase	1	0.950	-	0	Normalized mean entropy	S5046
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm42461
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.640