Protein Alignment Ugt35E2 and Ugt3a2

DIOPT Version :10

• Sequence 1: NP_652623.2
• Gene: Ugt35E2 / 53506
• FlyBaseID: FBgn0040255
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_997099.2
• Gene: Ugt3a2 / 105887
• MGIID: 2146055
• Length: 523
• Species: Mus musculus
• Alignment Length: 553
• Identity: 150/553 - (27%)
• Similarity: 254/553 - (45%)
• Gaps: 84/553 - (15%)

  Fly    10 LIVLVVALLPVLLEGARILGVFPIPSHSHYYHALPYLKKLASLGHEIT-------SVSPFPLKEP 67
            |:|....|..:|||.|:||.:..: |.|||.......:.|...||::.       .:..|..:..
Mouse     8 LLVSFFLLEVLLLEAAKILTISTL-SASHYILMNRVSQILQGGGHDVIKLLYEGGDIPDFRKENS 71

  Fly    68 VANIHDIPVPE----LFDN-IEEIVGNLTNRKGTWNEFEYINQYTLGLVEKVLENDGVRREILQP 127
            ...:.:..:||    .|:| ...::......:..::....|:||...|...:|....: .|:||.
Mouse    72 SYQVINWRLPEDQQKTFENRWHRLIDEYAYGRSKYHTLLKIHQYFADLCSHLLSRKDI-MELLQK 135

  Fly   128 ESLQFDLIIVDLWRLDALYGLAAYFDAPIIGIASYGTDWKIDELVGN--VSPLAYLQSPSFNWFD 190
            |:  |||:::|...|                     ..:.|.|.:|.  ||.|.:    .|::.|
Mouse   136 EN--FDLVLLDSMDL---------------------CSFLIVEKLGKRFVSFLPF----QFSYMD 173

  Fly   191 L----------DTYGGRLGHFVDQSMAW-------INWHWRHEERHEAVYRKYFPKIAD------ 232
            .          ..||..|   .||...|       :.:|:..:.|.  ::.:|...:.:
Mouse   174 FGLPNAPLSYAPVYGSGL---TDQMDFWGRVKNILMFFHFTKKRRD--IFSQYGNTVQEHFAEGS 233

  Fly   233 KRSLSEITRNFALILVNQHFTMAPPRPYVPNIIEVGGMHVDQQPKALPQDLEDFIQGAGEHGVIY 297
            :..||::.....|..||..|.:...||..||.:.|||: :|:..:.:||||||||...|:.|.:.
Mouse   234 QPVLSDLLLKAELWFVNSDFALDFARPLFPNTVYVGGL-LDKPVQPIPQDLEDFISQFGDSGFVL 297

  Fly   298 FSLGTNVRSRNLSKDRRKILIDTFASLPQRILWKFDAD----ELSDVPSNVLISPWFPQQDILAH 358
            .:|| :|.|...||:..|.:...||.|||.:||...:.    ::|..| ||.|..|.||.|:|||
Mouse   298 VALG-SVVSMIQSKEIIKEMNSAFAHLPQGVLWTCKSSHWPKDVSLAP-NVKIMDWLPQIDLLAH 360

  Fly   359 PNVKLFITHGGLQSTVECIHRGVPMLGLPFFYDQFRNMEHIKAQGIGLVLNYRDMTSDEFKDTIH 423
            |:::||:||||:.|.:|.:|.||||:|:|||.||..||..::|:.:|:.:..:.:.::.|..|:.
Mouse   361 PSIRLFVTHGGMNSVMEAVHHGVPMVGIPFFGDQPENMVRVEAKNLGVSIQLQTLKAESFLLTMK 425

  Fly   424 QLLTEKSFGVKAKRTADRYRDQPMNPLDTAIWWTHYVLRHKGAPHMRVAGRNLDFITYHSLDV-- 486
            :::.::.:...|..:....:..|:.|....:.|..::|:..||.|::.......:...:.|||
Mouse   426 EVIEDQRYKTAAMASKVIRQSHPLTPAQRLVGWIDHILQTGGAAHLKPYAFQQPWHEQYMLDVFL 490

  Fly   487 --LGTFLLAVWAILSIVVLCAIKLLRAILKSKK 517
              ||..|..:|  ||:.||.|:....:|.:..|
Mouse   491 FLLGLTLGTLW--LSVKVLVAVTRYLSISRKVK 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35E2	NP_652623.2	MGT	31..443	CDD:273616	120/452 (27%)
		Glycosyltransferase_GTB-type	<247..517	CDD:471961	94/277 (34%)
Ugt3a2	NP_997099.2	Glycosyltransferase_GTB-type	24..488	CDD:471961	130/500 (26%)